January 2016 in “Lithuanian University of Health Sciences” This study in a Lithuanian veterinary clinic observed diverse histomorphological skin changes in alopecic dogs caused by various rare diseases, including hyperkeratinization and pigmentation disorders.
In this study, penetration of FA-PLGA nanoparticles into hair follicles was observed in excised dog, rat, and porcine skin, with the deepest penetration in porcine skin, suggesting its similarity to human skin for drug delivery studies.
January 1996 in “TURKISH JOURNAL OF VETERINARY AND ANIMAL SCIENCES” This study examined the skin structure of European Brown Bears, finding that the thickest skin is on the back and the thinnest on the ventral abdomen, with distinct layers and fiber networks.
46 citations
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December 2018 in “Biomedical Optics Express” In this study, researchers observed that Raman spectroscopy effectively differentiates basal cell carcinoma from normal skin structures by analyzing biochemical markers, suggesting its potential as a surgical guidance tool for cancer margin resection during Mohs surgery.
April 2017 in “Journal of Investigative Dermatology” This study identified five master regulators that mediate molecular differences in hair follicle development and sexual dimorphism in the skin, providing insights into male pattern baldness and hair follicle donor dominance.
168 citations
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August 2000 in “American Journal of Pathology” This study suggests that fibromodulin may regulate transforming growth factor-β activity during scar formation, influencing the transition from fetal scarless repair to adult scar-forming repair in rats.
11 citations
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April 2013 in “SpringerPlus” This study reports that melanocytes form a defined photoresponsive network in the skin that reads environmental light cycles and may influence the sleep-waking cycle similar to the pineal gland.
9 citations
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July 2018 in “International Journal of Dermatology” This study suggests that yellow and white dot signs may be new dermoscopic indicators of advanced androgenetic alopecia in dark-skinned females, with certain trichoscopic features associated with darker skin types.
4 citations
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March 2020 in “BMC Research Notes” In this study of Irish adults with morbid obesity, skin tags were associated with higher blood pressure, HbA1c levels, and a greater prevalence of diabetes and hypertension, indicating increased cardiovascular risk.
3 citations
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January 2023 in “Journal of Cutaneous and Aesthetic Surgery” Intradermal PRP significantly improved melasma in dark skin, with lasting results and no relapse after 3 months.
1 citations
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July 2021 in “Chemical & pharmaceutical bulletin/Chemical and pharmaceutical bulletin” This study found that rubbing significantly increased skin permeation of caffeine but not rhododendrol, with the direction of rubbing playing a crucial role in caffeine's enhancement.
1 citations
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January 2025 in “Poultry Science” In this study, researchers examined skin growth and quality in Pekin ducks from 1 to 6 weeks of age, finding that skin factors like strength and collagen content increased with age and were influenced by gene expressions related to cell proliferation and collagen synthesis.
May 2026 in “Applied Sciences” In this review, the authors reported that sprout extracts, rich in bioactive compounds, show promising effects on skin health, such as enhancing collagen synthesis, improving hydration, and reducing inflammation, though most evidence comes from laboratory and animal studies.
September 2025 in “Middle East Current Psychiatry” In this study, caregivers of patients with chronic skin diseases such as psoriasis, vitiligo, and alopecia areata reported significant burdens, including stress and lack of time, which negatively impacted their quality of life, particularly in those caring for psoriasis patients.
March 2025 in “Pain Physician” This retrospective study found that applying local skin precooling before scalp nerve block significantly reduced injection site pain during PRP mesotherapy for patients with androgenetic alopecia, compared to those who did not receive precooling, thus improving patient comfort and compliance.
October 2024 in “Cosmetics” This study found that while most women reported aesthetic improvement after PRP facial injections, objective skin analyzer data showed no significant changes, but midface volume improvement was more likely in those with lower platelet counts and higher estradiol levels.
September 2024 in “Journal of the American Academy of Dermatology” This study found that MF patients with darker skin types show slower initial improvement with NB-UVB phototherapy, highlighting disparities in treatment efficacy that warrant further investigation.
July 2024 in “Journal of Cosmetic Dermatology” In this clinical study, a vegan collagen builder (VEGCOL™️) was shown to safely and effectively improve hair growth, skin smoothness, wrinkle reduction, and joint pain relief in adults, with enhancements varying by dose over a 60-day period.
December 2023 in “Dermatologic Surgery” The researchers reported that using a skin-responsive FUE device in nonscalp hair transplantation significantly reduced graft transection rates compared to older methods, improving patient satisfaction and surgeon willingness.
November 2014 in “The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology” This study found that dry skin, dandruff, and scalp issues were common among healthy Korean subjects, indicating a need for more research on their skin characteristics.
69 citations
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June 2017 in “Experimental Biology and Medicine” This review discusses the advancements and challenges in developing in vitro human skin models incorporating components like vasculature for drug testing and disease research, but reports no new clinical results.
249 citations
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April 2002 in “The FASEB journal” This study provides evidence that human skin contains genes and enzymes necessary for producing serotonin and melatonin.
39 citations
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January 2020 in “Scientific Reports” This study identified four circRNAs with significantly different expression levels in Liaoning cashmere goats, suggesting a potential role in regulating cashmere fineness.
30 citations
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December 2014 in “BMC Genetics” This study found thousands of differentially expressed genes and proteins that may be associated with wool growth, suggesting potential gene families involved in hair growth regulation.
23 citations
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July 2020 in “BMC Genomics” This study identified a stable combination of house-keeping genes, NCBP3 + SDHA + PTPRA, for normalizing gene expression in goat skin tissues using RNA sequencing.
8 citations
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August 2016 in “Journal of pathology and translational medicine” This study found that CD99 is strongly expressed in the basal cells and hair follicles of normal adult and developing fetal skin, with expression patterns becoming similar after 20 weeks of gestation.
8 citations
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February 2002 in “Journal of Medical Genetics” In this study, synchrotron fibre diffraction identified changes in dermal collagen microfibrillar radius with age, with lower radii observed in individuals with insulin-dependent diabetes mellitus.
7 citations
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January 2025 in “Frontiers in Microbiology” In this study, researchers investigated the immunohistopathological characteristics of the skin in individuals during the acute phase of chikungunya infection, revealing CHIKV antigens and inflammatory infiltrates in various skin components and highlighting the role of cytokines/chemokines in the disease's skin manifestations.
5 citations
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June 2017 in “in Vivo” This study found that vitamin C deficiency in SMP-30/GNL-KO mice affected gene expression related to hair growth and cell growth, resulting in delayed hair growth compared to those with adequate vitamin C.
2 citations
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February 2018 This study found that Raman spectroscopy has potential for detecting biophysical differences in basal cell carcinoma compared to normal skin structures, supporting its future use in Mohs surgery.