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Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

The document concludes that patients with skin of color need specialized dermatological care and education to manage unique skin conditions effectively.

Retinol acetate can reduce the harmful effects of the drug benoxaprofen on white blood cells.

The enzyme 17β-HSD type 2 mainly performs oxidation in human sebaceous glands, which may help protect against acne.

Minoxidil may help treat hair loss by reducing inflammation-related gene activity in skin cells.

Chronic stress in mice changes skin metabolism and gene expression, leading to hair loss.

The new recombinant human collagen can help slow skin aging and repair skin, while also controlling inflammation.

Proretinal nanoparticles are a safe and effective way to deliver retinal to the skin.

The enzyme RDH12 plays a role in vision and retinal disease, with mutations leading to early onset visual loss and blindness, but the exact disease mechanism is unclear and there are no treatments yet.

SCD1 is crucial for skin health and overall energy balance.

Bee pollen, green tea, essential oils, and various plant extracts improve skin and hair health.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

A new cosmetic cream reduced facial redness and skin temperature after 4 weeks of use.

The skin produces and processes hormones, affecting both local and overall body functions.

Herbal hair serum promotes natural hair growth and maintains healthy hair.

The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.

Pomiferin may improve skin and hair by increasing important protein production.

HtrA2 activity is crucial for normal hair growth by regulating fat cell development.

Natural ingredients in cosmeceuticals are beneficial for skin and hair health with few side effects.

Notch signalling helps skin cells differentiate and prevents tumors.

The Notch signaling pathway helps in mouse hair development through a noncanonical mechanism that does not rely on RBPj or transcription.

Microneedles improve drug delivery in various body parts, are safe and painless, and show promise in cosmetology, vaccination, insulin delivery, and other medical applications.

RXRα is crucial for proper immune response and links diet to immune function.

Aging causes hair loss and graying due to stem cell decline and changes in cell behavior and communication.

9-cis-retinoic acid showed some effectiveness in treating AIDS-related Kaposi sarcoma but had significant side effects at higher doses.

BMPR1a-ECD reduces wrinkles much more effectively than retinoic acid.

Using defensins to activate stem cells may improve skin aging signs without causing inflammation.

Minoxidil and retinol together help hair grow.

Blocking DGAT1 reduces oil gland size in mice and dogs, but only mice experience hair loss.

Women with idiopathic hirsutism and PCOS have higher RBP4 levels, and PCOS is linked to greater insulin resistance; weight management may help both conditions.