research An Open Label Clinical Trial of the JAK Inhibitor Tofacitinib for Alopecia Areata
Tofacitinib helped over half of the patients with severe hair loss regrow at least 50% of their hair.
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research Induction of Insulin-Like Growth Factor-I by Cepharanthine from Dermal Papilla Cells: A Novel Potential Pathway for Hair Growth Stimulation
Cepharanthine may help hair growth by increasing IGF-I in scalp cells.
research Imiquimod-Induced Effluvium After Intravaginal Application for Treatment of Cervical Intraepithelial Neoplasia
Imiquimod used intravaginally for cervical issues can cause temporary hair loss, especially if severe side effects occur.
research Hair Follicle Aging Is Driven by Transepidermal Elimination of Stem Cells via COL17A1 Proteolysis
Hair loss and aging are caused by the breakdown of a key protein in hair stem cells.
research Tendency to Underestimate the Severity of Androgenetic Alopecia
People often underestimate hair loss severity, with fewer seeking treatment, and it's more distressing for women.
research Transgenic HPV11-E2 Protein Modulates URR Activity In Vivo
The E2 protein affects gene activity in hair follicles of mice.
research Female Pattern Hair Loss, Biological Aging, and the Leiden Longevity Study
Women with aging signs and heart issues have higher hair loss risk, which may predict shorter lifespan and affect attractiveness.
research Isotretinoin
Isotretinoin is a preferred treatment for severe acne, often leading to long-term improvement, but requires careful monitoring due to potential side effects.
research Nevus Sebaceus With Novel HRAS Sequence Variant Mutation Misdiagnosed As Alopecia Areata
A 12-year-old girl was misdiagnosed with alopecia areata but actually had a nevus sebaceus with a genetic mutation.
research Hyperpigmentation and Melasma
Hyperpigmentation is common in pregnancy and may not fully fade after birth; melasma, also frequent, can persist but has limited treatment options during pregnancy.
research The Hair Cycle of the Mouse and Its Importance in the Study of Sequences of Experimental Carcinogenesis
Understanding the mouse hair cycle is crucial for cancer research.
research Lichen Planopilaris: Chronic Scarring Alopecia with Autoimmune Component
Lichen planopilaris is a chronic, scarring hair loss condition with no definitive cure, requiring accurate diagnosis and treatment to manage symptoms.
research Efficacy of Imiquimod 5% Cream in the Treatment of Equine Sarcoids: A Pilot Study
Imiquimod 5% cream reduced equine sarcoids in most cases.
research Topical Immunotherapy in Alopecia Areata
Topical immunotherapy, especially with DPCP, is effective for treating severe alopecia areata.
research The Basic Science of Hair Biology
Hair disorders are caused by a complex mix of biology, genetics, hormones, and environmental factors, affecting hair growth and leading to conditions like alopecia.
research Becker's Nevus with Ipsilateral Breast Hypoplasia: Improvement with Spironolactone
Spironolactone may help enlarge a small breast linked to Becker's nevus.
research The HPV16 Oncogenes Cause Aberrant Stem Cell Mobilization
HPV16 oncogenes disrupt the normal activity of hair follicle stem cells.
research Significance of Iron Status in Hair Loss in Women
Iron deficiency might contribute to hair loss in women.
research The Effect of Proteolytic Enzymes on Hair Follicles of Transgenic Mice Expressing the Lac Z-Protein in Cells of the Bulge Region
Proteolytic enzymes damage hair follicles by detaching stem cells.
research Case 33-2015
The woman's surgery lowered her testosterone and improved scalp hair loss but did not change her excessive body hair.
research Index
research The Role of Wnt and Shh Signaling Systems in Noggin-Induced Tumorigenesis
Wnt and Shh signaling are key in noggin-induced tumors, and blocking them can slow tumor growth.
research Updates in the Pathogenesis of Alopecia Areata
Alopecia areata is an autoimmune condition causing hair loss, linked to genetic factors and immune system issues, with no cure yet.
research Different Polyamine Levels in the Vertex and Occipital Hair of Pattern Hair Loss Patients
People with pattern hair loss have higher polyamine levels in the top of their head compared to the back.
research Alopecia: The Questions We Need to Answer
We need better research to improve alopecia treatment and patient care.
research Interferon Alfa-2a in the Treatment of Cutaneous T Cell Lymphoma
Interferon alfa-2a is effective for treating cutaneous T cell lymphoma but has significant side effects.
research Hormonal Therapy for Acne: Why Not as First Line Therapy? Facts and Controversies
Hormonal treatments can help with acne but are not the first choice due to side effects and the need for careful patient selection.
research C-MYC-Induced Sebaceous Gland Differentiation Is Controlled by an Androgen Receptor/p53 Axis
The balance between androgen receptor and p53 is crucial for sebaceous gland differentiation.
research Lack of Efficacy of Topical Latanoprost and Bimatoprost Ophthalmic Solutions in Promoting Eyelash Growth in Patients with Alopecia Areata
Topical latanoprost and bimatoprost eye solutions don't help eyelash growth in people with alopecia areata.
research Finasteride for Female Androgenetic Alopecia
Finasteride increases hair density in female androgenetic alopecia, but individual results may vary.