176 citations
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August 2000 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” In this study, cross-sex hormone therapy affected hair growth patterns differently, with estrogen reducing hair growth in male-to-female transsexuals and testosterone increasing it in female-to-male transsexuals; however, male typical hair diameters were not fully reached in the latter group after 12 months.
14 citations
,
December 2013 in “Experimental Dermatology” The T-zone on the face has more androgen receptors and produces more oil than the U-zone.
September 2014 in “Springer eBooks” This review discusses how sex hormone levels and local steroid synthesis influence gender differences in aging skin, reporting no new clinical results.
December 2025 in “International Journal of Molecular Sciences” In this study, O. forskahlii seed oil was found to promote hair growth in rats and exhibit anti-aging effects on human skin cells by enhancing fibroblast proliferation and inhibiting inflammation and enzyme activity, indicating potential for cosmetic use.
January 2017 in “Isan Journal of Pharmaceutical Sciences” This study explored microemulsion formulations for delivering finasteride through the skin, finding that higher water concentrations increased permeation, which may inform optimal transdermal delivery for treating androgenetic alopecia.
45 citations
,
September 2000 in “Archives of dermatology” This study found that 5alpha-reductase type 1 localizes specifically to sebaceous glands in both normal and acne follicles, suggesting its role in sebum regulation.
23 citations
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August 2018 in “Facial Plastic Surgery Clinics of North America” This review discusses the role of defensin peptides in stem cell activation for potential skin rejuvenation therapies and reports no new clinical findings, emphasizing the need for further studies.
This article reviews the effects of combined oral contraceptives on skin conditions and suggests prescribing guidelines for women with acne, as it reports no new clinical results.
47 citations
,
September 2016 in “Reviews in endocrine and metabolic disorders” This review discusses the steroidogenic properties of human skin and suggests that impaired steroidogenesis may be linked to conditions like acne, rosacea, atopic dermatitis, and androgenic alopecia, but reports no new clinical results.
18 citations
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October 2024 in “Medical Science Monitor” This review discusses the mechanisms of skin barrier impairment in acne vulgaris and suggests strategies for its repair but reports no new clinical results.
July 2012 in “The Journal of Urology” This abstract reviews testosterone supplementation with and without a dual 5α-reductase inhibitor on fat-free mass in men with suppressed testosterone production and reports no new research findings.
40 citations
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January 2016 in “Elsevier eBooks” This article explains the structure and multifunctional roles of the human skin, including its protective, regulatory, and sensory functions, but does not report new research findings.
6 citations
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January 2009 in “Elsevier eBooks” This chapter discusses the structure and function of the skin, detailing its protective roles and the layers that comprise it, but reports no new research findings.
137 citations
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June 2005 in “Climacteric” This review indicates that estrogen loss during menopause significantly impacts skin health, while estrogen treatment may increase skin collagen, thickness, and elasticity, though effects on other skin characteristics are inconsistent.
68 citations
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June 2005 in “Expert Opinion on Therapeutic Targets” This review discusses the influence of oestrogens on various skin components and highlights their modulatory roles and receptor pathways, but it reports no new clinical results.
27 citations
,
March 2006 in “Journal of cosmetic dermatology” This review examines the effects of menopause on skin aging and suggests hormone replacement therapy may improve some symptoms, without providing new clinical findings.
September 2023 in “The Journal of Dermatology” In this 2-year prospective study, researchers observed that weight loss through bariatric surgery in patients with morbid obesity led to improvements in various skin conditions, although it also resulted in hair loss (telogen effluvium) for over half of the participants.
April 2023 in “Journal of Investigative Dermatology” In this study, bariatric surgery in patients with morbid obesity improved various skin conditions, although acute telogen effluvium was common, with notable reductions in facial sebum and skin elasticity changes.
1 citations
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October 2025 in “International Journal of Morphology” This study found that virgin coconut oil improved skin inflammation and symptoms of seborrheic dermatitis in rats, particularly at a dose of 10 mg/kg, by reversing alterations in antioxidant and inflammatory markers.
35 citations
,
January 2011 in “Journal of Biological Chemistry” This study found that overexpression of sPLA2-X in mice was associated with alopecia and hair follicle abnormalities, highlighting its potential role in hair follicle homeostasis.
11 citations
,
November 2022 in “Journal of Endocrinological Investigation” In this study, gender-affirming hormonal treatment was associated with increased hair growth, acne, and alopecia prevalence in transgender individuals assigned female at birth, while opposite dermatological changes were observed in those assigned male at birth.
10 citations
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January 2013 in “Actas Dermo-Sifiliográficas” Most white Spanish women have a widow's peak, and their hairline measurements could help in hair restoration surgery.
July 2025 in “Journal of Investigative Dermatology” Acne involves increased lipid production and inflammation, affecting skin cell behavior and treatment resistance.
August 2011 in “동의생리병리학회지 = Journal of physiology & pathology in Korean Medicine” In this study, treatment with Green tea was found to significantly increase cholesterol and triglyceride levels in sebocyte cells in a dose-dependent manner.
June 2026 in “International Journal of Innovative Technologies in Social Science” This review highlights the broad range of adverse effects associated with isotretinoin in acne treatment and examines strategies such as dietary supplementation and adjusted dosing protocols to enhance patient tolerability while maintaining efficacy.
57 citations
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February 2016 in “Dermatologic surgery” This review identifies excessive sebum, decreased elasticity, and increased hair follicle volume as key factors contributing to enlarged skin pores, emphasizing the need for individualized treatment based on underlying causes.
3 citations
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October 2019 in “CRC Press eBooks” This review discusses isotretinoin's effectiveness against severe acne vulgaris and its associated side effects, including teratogenicity and hair loss, but it reports no new experimental results.
1 citations
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January 2023 in “Middle East Research Journal of Pharmaceutical Sciences” This review discusses the mechanisms and grading challenges of acne vulgaris, highlighting the need for better treatment strategies and reports no new experimental results.
April 2024 in “Molecules/Molecules online/Molecules annual” This review discusses the potential of P. polyphylla saponins to treat acne through antibacterial, anti-inflammatory, immunomodulatory, and antioxidant effects, noting that acne's complex pathogenesis makes this line of research promising for future studies.
This study reviews the regulatory mechanisms and molecular processes governing stem cell activity in hair follicles, highlighting their roles in hair regeneration and potential implications for treating hair and skin disorders.