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The new compounds moderately block a specific enzyme and strongly counteract a male hormone, suggesting potential for treating certain male-related health conditions.

Witch hazel-based hair products improved scalp irritation and were well-tolerated.

Flutamide, an antiandrogen, has minimal impact on female rat endocrine systems and does not significantly change their reproductive cycles.

Different animals have unique versions of the enzyme that changes testosterone into another hormone, which is important for creating effective treatments for prostate and hair loss conditions.

New compounds called benzoquinolinones may treat conditions linked to excess DHT.

Some women with acne have higher levels of free testosterone, which might suggest using hormonal treatments for acne.

Excessive hair growth can be assessed by history, exam, and blood tests, and treated with medication like dexamethasone, birth control pills, and spironolactone.

Young women with diffuse hair loss may have low SHBG levels, which could lead to more active testosterone and contribute to their hair loss.

A witch-hazel-based 5% minoxidil solution is effective and safe for women with hair loss who didn't respond to regular minoxidil, especially if they're sensitive to propylene glycol.

High levels of 3 alpha-diol glucuronide in the blood are a marker of increased androgen action in women with excessive hair growth of unknown cause.

Higher insulin levels are linked to larger ovaries in women with idiopathic hirsutism.

Mouse cell exosomes help hair regrowth and wound healing by activating a specific signaling pathway.

People with hair loss conditions may also have thyroid disorders, but more research is needed to understand the connection.

Melatonin in the skin helps protect against damage from stress and UV rays, and could be used to treat certain skin conditions.

The study created a new method to test drugs that affect hormone processing in skin.

Keratinocytes help manage skin nitrogen metabolism, varying by age and skin area.

sPLA2-IIE is crucial for normal hair follicle structure and skin health.

Thyroid hormones are important for skin health and changes in them can affect conditions like hair loss and eczema.

The document suggests that blocking sweat glands with antiperspirants might allow skin-generated hormones to be absorbed, possibly increasing breast and prostate cancer risk.

Lipin-1 is important for skin cell differentiation and skin barrier function.

Some skin problems can be signs of diabetes or other metabolic diseases and recognizing them can help diagnose and treat these diseases early.

The enzyme 17β-HSD type 2 mainly performs oxidation in human sebaceous glands, which may help protect against acne.

The ABCA4 gene protects hair follicle stem cells from toxic vitamin A byproducts.

Skin changes can indicate hormonal imbalances and help diagnose endocrine disorders.

Visible light can improve skin disorders and hair loss, but more research is needed to understand long-term effects.

Rabbit skin analysis showed changes in hair growth and identified miRNAs that may regulate hair follicle development.

Reduced androgens linked to kinky hair disorder and hair loss; 5a-reductase inhibitors may help.

Healthy mitochondria in skin cells are essential for proper hair growth and skin cell interaction in mice.

Different sPLA2 enzymes affect immunity, skin and hair health, reproduction, and may be potential targets for therapy.

Light-based treatment, Photobiomodulation, shows promise for non-invasive skin therapy with few side effects.