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Overexpressing the mineralocorticoid receptor in mouse skin causes skin thinning, early skin barrier development, eye issues, and hair loss.

Skin problems can be caused or worsened by physical forces and pressure on the skin.

Macrophages are vital for skin healing, hair growth, salt balance, and cancer defense.

Keratins are important for skin cell health and their problems can cause diseases.

Wound dressing absorbs fluid, regenerates hair follicles, and heals skin burns.

Men are more likely to get infectious skin diseases, while women are more prone to autoimmune and pigment-related skin conditions, influenced by biological and environmental factors.

Organotypic culture systems can grow skin tissues that mimic real skin functions and are useful for skin disease and hair growth research, but they don't fully replicate skin complexity.

Engineered skin substitutes can grow hair but have limitations like missing sebaceous glands and hair not breaking through the skin naturally.

MicroRNAs play a crucial role in skin and hair health, affecting everything from growth to aging, and could potentially be used in treating skin diseases.

Hair follicle regeneration in skin grafts may be possible using stem cells and tissue engineering.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Adult skin quickly reacts to short-term environmental and internal stress, leading to various skin issues and the need for protective measures.

Spiny mice are better at regenerating hair after injury than laboratory mice and could help us understand how to improve human skin repair.

Endo-HSE helps grow hair-like structures from human skin cells in the lab.

New treatments targeting skin stem cells show promise for skin repair, anti-aging, and cancer therapy.

Stronger corticosteroids cause more skin damage in hairless dogs, similar to effects in humans.

Skin and hair can help us understand organ regeneration, especially how certain stem cells might be used to form new organs.

The protein SLC1A3 is important for activating skin stem cells and is necessary for normal hair and skin growth in mice.

Thyroid hormones are important for skin health and changes in them can affect conditions like hair loss and eczema.

Skin organoids are a promising new model for studying human skin development and testing treatments.

Hair follicle stem cells and skin cells show promise for hair and skin therapies but need more research for clinical use.

Hair follicles on the scalp interact with and respond to the nervous system, influencing their own behavior and growth.

New skin substitutes for treating severe burns and chronic wounds are being developed, but a permanent solution for deep wounds is not yet available commercially.

Early recognition and management of skin side effects from new cancer therapies can prevent treatment delays.

The document concludes that there is a significant lack of reporting on the sex and age of cells in skin research, which could affect clinical trials and treatments.

Technique effectively treats deformities, achieves re-pigmentation, and releases scar contractures.

Skin aging is caused by stem cell damage and can potentially be delayed with treatments like antioxidants and stem cell therapy.

Genetic variants linked to ten skin diseases were found, showing both immune and non-immune factors play a role.

Thyroid diseases may contribute to autoimmune skin diseases, and more research is needed on their relationship.

Dermal papillae cells, important for hair growth, come from multiple cell lines and can be formed by skin cells, regardless of their origin or hair cycle phase. These cells rarely divide, but their ability to shape tissue may contribute to their efficiency in inducing hair growth.