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Surgical therapies for vitiligo vary in effectiveness, with combination therapy and medical tattooing recommended for better results.

Transplanting small skin grafts can successfully repigment leukoderma.

Understanding repigmentation mechanisms in vitiligo can improve treatments and patient outcomes.

As people age, their hair follicles produce less pigment, leading to gray and white hair, due to factors like reduced enzyme activity and damage to melanocyte DNA.

Hair color is determined by different melanins and changes with age.

Hair color is determined by melanin and can be affected by genetic conditions like albinism.

Cathepsin L is essential for normal hair growth and development.

Generalized vitiligo in Chinese patients is linked to other autoimmune diseases, especially in familial cases.

Genetic defects and UV radiation cause skin damage and aging.

Estrogen therapy can reduce skin aging but has cancer risks.

Hair graying is caused by the loss of pigment cells due to poor maintenance of stem cells in the hair follicle.

The study identified unique genes in hair follicle cells and their environment, suggesting these genes help organize cells for hair growth.

Blocking mTORC1 activity with rapamycin could help increase hair pigmentation and growth, potentially reversing gray hair.

An 8-year-old boy had both alopecia areata and vitiligo on the same spot on his scalp, which is very rare.

Fish oil improves skin health in people with diabetes and high cholesterol.

Oestrogens help maintain healthy skin, heal wounds, and may protect against skin aging and cancer.

Fat cells are important for healthy skin, hair growth, and healing, and changes in these cells can affect skin conditions and aging.

Regenerative therapies show promise for treating vitiligo and alopecia areata.

Vitiligo treatments include JAK inhibitors, UVB phototherapy, and dietary changes, with emotional support being important.

Melanocytes might be targeted by the immune system in people with alopecia areata, but more research is needed.

Local skin glucocorticoid production is crucial for healthy skin, and its disruption can lead to skin diseases.

Genetic research has advanced our understanding of skin diseases, but complex conditions require an integrative approach for deeper insight.

A man's scalp hair loss was due to a combined melanocytic nevus and alopecia areata, suggesting a possible link between the two conditions.

The document concludes that adult mammalian skin contains multiple stem cell populations with specific markers, important for understanding skin regeneration and related conditions.

ISCK03 stops melanin production in human melanoma cells and lightens skin color in mice and guinea pigs.

A certain signaling pathway in mice, when increased, causes hair to gray by depleting the cells that give hair its color.

The created skin model with melanoblasts improves the study of skin color and offers an alternative to animal testing.

Segmental vitiligo affects hair follicle melanocytes, causing small, uniform depigmented spots.

Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.

Exosomes from stem cells may help rejuvenate skin and regrow hair, but more research is needed.