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Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Metformin is effective for treating excessive hair growth in women with PCOS and may work better than the standard treatment in some ways.

Experts recommend thorough medical, sexual, and psychosocial assessments for women's sexual dysfunctions, and suggest individualized treatment plans with regular check-ups. They also mention potential use of estrogen and androgen therapy, but with caution due to safety concerns.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

Testosterone therapy in transgender men has both desired effects like increased muscle mass and potential health risks such as higher cardiovascular risk.

Hormone therapy is essential for transgender individuals but requires careful management due to possible metabolic effects.

Surgeons must understand the full care process for gender confirmation surgery to help transgender individuals effectively.

Isotretinoin effectively treats severe acne and similar conditions, but has common, mostly reversible side effects, requiring careful patient monitoring.

Hibiscus plant extracts may have health benefits like lowering blood pressure and protecting the heart.

Adult female acne treatment should be personalized, considering individual preferences and pregnancy, using various topical and oral medications while managing side effects and resistance.

Dihydrotestosterone gel improved well-being and sexual function in older men without negatively affecting prostate health.

DHT may increase the risk of heart disease and death in elderly men.

The document concludes that proper diagnosis and a multidisciplinary approach are crucial for managing Congenital Adrenal Hyperplasia effectively.

Spironolactone most effective for hirsutism, but has side effects.

The conclusion is that early diagnosis and a multi-system treatment approach are crucial for managing PCOS and its associated health risks.

Women with PCOS have more body fat and thicker fat layers in certain abdominal areas than women without PCOS.

The conclusion is that managing androgen excess requires long-term treatment, including hormonal contraceptives and androgen blockers, with follow-up after six months.

New treatments for male hypogonadism are effective and should be personalized.

PCOS is a common hormonal disorder in women, treated with lifestyle changes and medications like hormonal contraceptives and metformin.

Testosterone treatment effectively causes male physical development in transgender male adolescents but may lead to side effects like acne, higher BMI and blood pressure, lower good cholesterol, and decreased bone density.

PCOS affects women's health by increasing the risk of diabetes, heart disease, and reproductive issues.

The conclusion is that published guidelines are improving transgender medical care, but more research and education in transgender medicine are needed.

Doctors need to be better prepared to assess and treat obesity in patients.

The review recommends hormone replacement therapy for women with premature ovarian insufficiency to manage symptoms and protect health, with specific approaches for different groups.

SHBG may be a useful early indicator and treatment target for PCOS.

Hormone treatment for transgender patients may not need to be stopped before surgery, but more research is needed, especially on estrogen.

Athletes use steroids to enhance performance despite health risks and legal issues, and education on their dangers is needed.

Edible seeds from the Cucurbitaceae family like pumpkin and watermelon seeds are nutritious and may have health benefits, but eating too much can cause side effects.

The document concludes that recognizing and properly diagnosing lipodystrophy syndromes is crucial for effective management and treatment.

The document concludes that Nonclassic Congenital Adrenal Hyperplasia requires personalized treatment plans to manage symptoms and fertility, with glucocorticoids being a common therapy.