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Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.

Skin cells produce and activate vitamin D, which regulates skin functions and supports hair growth.

Bone Morphogenetic Proteins (BMPs) help control skin health, hair growth, and color, and could potentially be used to treat skin and hair disorders.

Telocytes might help with skin repair and regeneration.

Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.

Memory T cells in the skin balance staying put and moving into the blood, clustering around hair follicles, and increasing in number after infection.

Male and female skin differ due to hormones, affecting conditions like hair loss, acne, and skin cancer, and suggesting a need for gender-specific treatments.

Estrogen therapy can reduce skin aging but has cancer risks.

Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.

Different types of stem cells with unique roles exist in blood, skin, and intestines, and this variety is important for tissue repair.

Estrogen loss during menopause worsens skin health, but hormone replacement therapy may improve it, though more research is needed.

Antibiotics can reduce acne but may lead to resistant bacteria, and understanding the skin's bacteria is important for treatment.

Different types of stem cells and their environments are key to skin repair and maintenance.

Skin grafts on mice can cause an immune response leading to hair loss, useful for studying human hair loss conditions.

Obesity is linked to various skin problems and may increase the risk of skin cancer.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

Cytokeratin 19 and cytokeratin 15 are key markers for monitoring the quality and self-renewing potential of engineered skin.

Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.

Correct skin biopsy techniques are crucial to avoid misdiagnosis of skin diseases.

Skin surface lipids are important for skin health and altering them could help prevent aging and treat skin conditions.

MicroRNA-214 is important for skin and hair growth because it affects the Wnt pathway.

The skin protects the body and is constantly renewed by stem cells; disruptions can lead to cancer.

Hair follicle regeneration needs special conditions and young cells.

EGF and KGF signalling prevent hair follicle formation and promote skin cell development in mice.

Skin has specialized touch receptors that can tell different sensations apart.

Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.

Restoring mitochondrial function in mice reversed their skin wrinkling and hair loss.

Pregnancy causes skin changes like darkening, hair thickening, nail changes, and increased risk of skin growths, most of which usually resolve after birth.

The p53 protein helps control hair follicle shrinking by promoting cell death in mice.