research Retinoids: New Uses and New Synthetic Agents
New retinoids are effective for various skin conditions and are being developed to have fewer side effects.
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research Therapeutic Control of Androgen Action
Understanding how androgens work is key for creating new treatments for prostate issues and hair/skin conditions.
research Clinical Applications of Antiandrogens
Antiandrogens are effective for conditions like prostate cancer and skin issues, but more research is needed to confirm their benefits and minimize side effects.
research Oral Syphilis: Report of Three Cases and Characterization of the Inflammatory Cells
The document concludes that recognizing oral lesions is important for diagnosing syphilis.
research Bilateral Ovarian Hyperthecosis: A Benign and Unusual Cause of Postmenopausal Hirsutism
Bilateral ovarian hyperthecosis is a rare but treatable cause of increased facial hair in postmenopausal women.
research Congenital Generalized Hypertrichosis With a Copy Number Variation on Chromosome 17q24
A girl with excessive hair growth had a genetic change on chromosome 17 that reduced the activity of two genes linked to hair growth.
research Genetically Null Mice Reveal a Central Role for Epidermal Growth Factor Receptor in the Differentiation of the Hair Follicle and Normal Hair Development
EGFR is essential for normal hair development and follicle differentiation.
research Dynamic Evaluation of Pathological Changes in a Mouse Acne Model by Optical Imaging Technology
New imaging techniques can assess and track changes in mouse acne without harm, aiding treatment choices.
research In Vivo Imaging of Mammary Epithelial Cell Dynamics in Response to Lineage-Biased Wnt/β-Catenin Activation
Activating β-catenin in mammary cells leads to changes that cause early-stage abnormal growths similar to skin structures.
research Cabergoline Therapy Against Hyperadrenocorticism in a Dog
Cabergoline effectively treated a dog's hyperadrenocorticism.
research Discriminating in Favor of or Against Men with Increased Risk of Finasteride-Related Side Effects?
Finasteride treats baldness but may cause lasting sexual side effects.
research The 5 Alpha-Reductase Isozyme Family: A Review of Basic Biology and Their Role in Human Diseases
The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.
research Homeostatic Control of Sebaceous Glands by Innate Lymphoid Cells Regulates Commensal Bacteria Equilibrium
Innate lymphoid cells help control skin bacteria by regulating sebaceous glands.
research Epithelially Derived MPZL3 Negatively Regulates Murine and Human Sebaceous Gland Size and Sebocyte Proliferation
MPZL3 protein helps control the size of oil glands and the growth of oil-producing cells in both mice and humans.
research LY191704: A Selective, Nonsteroidal Inhibitor of Human Steroid 5 Alpha-Reductase Type 1
LY191704 is a compound that effectively blocks a specific enzyme involved in hormone conversion and could help treat enlarged prostate and hair loss.
research Sebaceous Gland Diseases: Clinical Picture, Risk Factors, and Treatment
Different sebaceous gland diseases can be treated with medications, hormone therapy, or surgical methods.
research 5α-Reductase Inhibitors and Prostatic Disease
5α-Reductase inhibitors can help treat hair loss, acne, and prostate issues by reducing DHT levels.
research TNF Inhibitor Induced Alopecia: An Unusual Form of Psoriasiform Alopecia That Breaks the Renbök Mold
Some hair loss drugs can cause a unique type of hair loss that resembles both psoriasis and alopecia.
research Acne-Associated Syndromes
Acne is linked to inflammation and insulin resistance, and is associated with various syndromes that require different treatments.
research Post-Finasteride Syndrome: An Underestimated Phenomenon
Finasteride and dutasteride, used for prostate issues and hair loss, can cause side effects like sexual dysfunction and mental issues, which may continue even after stopping the medication, a condition called post-finasteride syndrome, for which there's currently no cure.
research 5α-Reductase Activity in the Prostate
Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.
research The Clinical Evaluation of Hirsutism
Hirsutism is excessive hair growth in women often caused by polycystic ovarian syndrome, and identifying the cause is important for managing associated health risks.
research Stimulating Effect of Adrenalectomy on Hair Growth and Melanin Deposition in Black Rats Fed Diets Adequate and Deficient in the Filtrate Factors of Vitamin B1
Adrenalectomy boosts hair growth and melanin in black rats, even with vitamin B¹ deficiency.
research Clinical Relevance of Testosterone and Dihydrotestosterone Metabolism in Women
Testosterone and dihydrotestosterone play a role in women's health issues like excess hair and baldness, and treatments blocking these hormones may help.
research Novel Tip-Loaded Dissolving and Implantable Microneedle Array Patches for Sustained Release of Finasteride
New dissolving and implantable microneedle patches have been created for a long-lasting, non-invasive delivery of the drug finasteride.
research Sponsored Lecture 3: Updates on 5 Alpha-Reductase Inhibitors (5ARIs) for the Treatment of Male Pattern Hair Loss (MPHL)
5AR inhibitors like finasteride and dutasteride improve hair growth and slow hair loss in male pattern baldness.
research Acne Syndromes and Mosaicism
Understanding how acne develops in different diseases could lead to new treatments.
research Editorial
The editorial discusses the effectiveness and safety of various laser and energy-based cosmetic treatments.
research Safety of Testosterone Use in Women
Short-term testosterone therapy in women seems safe with few mild side effects, but long-term effects need more research.
research Androgen Excess and Post-Reproductive Health
Excess male hormones in postmenopausal women can cause health issues and increase the risk of heart disease and diabetes; treatment depends on the cause.