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    Glossary Skin Homeostasis

    balanced state where skin maintains structure and function

    Skin homeostasis, also known as cutaneous homeostasis, refers to the balanced state of the skin where it maintains its structure, function, and appearance despite external and internal stressors. This involves a complex interplay of cellular processes, including cell regeneration, immune responses, and barrier function, ensuring the skin remains healthy and capable of protecting the body from environmental threats.

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    1. Epidermal homeostasis: a balancing act of stem cells in the skin Nature Reviews Molecular Cell Biology · 2009 · 1039 citations
    2. The role of fibroblast growth factor receptor 2b in skin homeostasis and cancer development The EMBO Journal · 2007 · 125 citations
    3. Recent advances in the epidermal growth factor receptor/ligand system biology on skin homeostasis and keratinocyte stem cell regulation Journal of Dermatological Science · 2013 · 97 citations
    4. The role of macrophages in skin homeostasis Pflügers Archiv - European Journal of Physiology · 2017 · 65 citations
    5. Alkaline ceramidase 1 is essential for mammalian skin homeostasis and regulating whole‐body energy expenditure The Journal of Pathology · 2016 · 38 citations
    6. The regulation of skin homeostasis, repair and the pathogenesis of skin diseases by spatiotemporal activation of epidermal mTOR signaling Frontiers in Cell and Developmental Biology · 2022 · 35 citations
    7. CD98hc (<i>SLC3A2</i>) regulation of skin homeostasis wanes with age 2013 · 35 citations
    8. Ruxolitinib protects skin stem cells and maintains skin homeostasis in murine graft-versus-host disease Blood · 2018 · 33 citations
    9. Thyroid hormone action in epidermal development and homeostasis and its implications in the pathophysiology of the skin Journal of endocrinological investigation · 2021 · 32 citations
    10. MicroRNAs in the skin: role in development, homoeostasis and regeneration Clinical Science · 2017 · 31 citations
    11. THY1-mediated mechanisms converge to drive YAP activation in skin homeostasis and repair Nature Cell Biology · 2022 · 23 citations
    12. The Role of the Slc39a Family of Zinc Transporters in Zinc Homeostasis in Skin Nutrients · 2018 · 19 citations
    13. Developmentally programmed early-age skin localization of iNKT cells supports local tissue development and homeostasis Nature Immunology · 2023 · 14 citations
    14. Unlocking the therapeutic potential of TRPV3: Insights into thermosensation, channel modulation, and skin homeostasis involving TRPV3 BioEssays · 2024 · 10 citations
    15. Epidermal PPARγ Is a Key Homeostatic Regulator of Cutaneous Inflammation and Barrier Function in Mouse Skin International journal of molecular sciences · 2021 · 9 citations
    16. Biotin Is Required for the Zinc Homeostasis in the Skin Nutrients · 2019 · 6 citations
    17. Acetyl-CoA synthesis in the skin is a key determinant of systemic lipid homeostasis Cell Reports · 2025 · 5 citations
    18. Grp1-associated scaffold protein regulates skin homeostasis after ultraviolet irradiation Photochemical & photobiological sciences · 2014 · 2 citations
    19. Characterisation of CD4+ stem cells of the skin and their role in skin homeostasis and tumourigenesis 2021 · 1 citations
    20. Gut Microbiota Shapes the Effects of Saturated and Polyunsaturated Fatty Acids on Skin and Hair Follicle Homeostasis Journal of Investigative Dermatology · 2026
    21. Effects of Glucagon-like Peptide-1 Receptor Agonists on Skin Homeostasis and Skin Aging Processes Journal of Clinical Medicine · 2026
    22. Erythrocyte Extracellular Vesicles Amalgamate into the Hair and Skin to Maintain Homeostasis Journal of Extracellular Vesicles · 2025
    23. Ligand-Independent Vitamin D Receptor Actions Essential for Keratinocyte Homeostasis in the Skin 2024
    24. Potential mechanisms of exercise in maintaining skin homeostasis disrupted by protein deficiency (Review) World Academy of Sciences Journal · 2024
    25. Sphingolipid metabolism orchestrates the establishment of the adult hair follicle stem cell niche to control skin homeostasis bioRxiv (Cold Spring Harbor Laboratory) · 2024
    26. The role of Kindlin-1 in skin homeostasis and tumor development Max Planck Digital Library · 2014
    27. Exploring molecular mechanisms controlling skin homeostasis and hair growth : microRNAs in hair-cycle-dependent gene regulation, hair growth and associated tissue remodelling Bradford Scholars (University of Bradford) · 2010
    28. Iron–Skin Axis: Exploring the Interplay between Iron Homeostasis and Skin Disorders Journal of Investigative Dermatology · 2025
    29. 852 Targeted deletion of crif1 in mouse skin epidermis impairs skin homeostasis Journal of Investigative Dermatology · 2017
    30. Retinol Esterification by DGAT1 Is Essential for Retinoid Homeostasis in Murine Skin 2008 · 91 citations