April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Scientists created skin-like structures from stem cells that include features like hair and sweat glands.
June 2016 in “CRC Press eBooks” Sleep problems and skin issues affect each other; poor sleep can worsen skin conditions, and some skin treatments can improve or harm sleep quality.
349 citations,
January 2005 in “The FASEB journal” Human skin can make serotonin and melatonin, which help protect and maintain it.
146 citations,
January 2004 in “Hormones” Human skin acts like a hormone-producing organ, making and managing various hormones important for skin and hair health.
81 citations,
February 2014 in “EMBO molecular medicine” Activating Nrf2 in skin cells causes skin disease similar to chloracne in mice.
36 citations,
February 2018 in “British Journal of Dermatology” Sweat glands and hair follicles are structurally connected within a specific layer of skin fat.
26 citations,
February 2022 in “Journal of pineal research” Melatonin affects skin and hair color and protects skin cells, with potential benefits for hair growth and skin health.
23 citations,
May 2019 in “Stem cell research & therapy” iPSC-derived stem cells on a special membrane can help repair full-thickness skin defects.
16 citations,
September 2016 in “Experimental Dermatology” Two-photon microscopy effectively tracks live stem cell activity in mouse skin with minimal harm and clear images.
16 citations,
August 2004 in “Tetrahedron” Scientists made all eight versions of a compound called cyoctol, but found it's not an anti-androgen and it fully breaks down in the skin.
14 citations,
May 2019 in “Experimental Dermatology” Fat tissue extract may help treat vitiligo by reducing cell stress and promoting skin repair.
6 citations,
December 2010 in “Journal of Investigative Dermatology” Albert M. Kligman made major contributions to dermatology, including inventing a stain for fungi and advancing knowledge on skin diseases, and his legacy continues through his trainees and philanthropy.
5 citations,
April 2022 in “Frontiers in Medicine” Hair and skin healing involve complex cell interactions controlled by specific molecules and pathways, and hair follicle cells can help repair skin wounds.
5 citations,
January 2021 in “Frontiers in cell and developmental biology” Skin cysts might help advance stem cell treatments to repair skin.
5 citations,
February 2010 in “Expert Review of Dermatology” Treating both the mind and skin together, especially by managing stress, can greatly improve outcomes for skin disorders linked to psychological issues.
4 citations,
October 2022 in “International Journal of Molecular Sciences” Thy-1 protein helps improve blood flow and wound healing in the skin.
3 citations,
September 2021 in “Journal of Food Science and Nutrition” Red Ginseng Extract helps hair grow and improves skin health by stimulating cell growth and enhancing the body's antioxidant defense system.
2 citations,
June 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” Epigenetic factors play a crucial role in skin health and disease.
2 citations,
June 2016 in “International journal of experimental pathology” Human skin has less GDNF and its receptor with age.
1 citations,
March 2023 in “Aggregate” A new hydrogel with micronized amnion helps achieve better, scar-free skin healing.
March 2024 in “International journal of molecular sciences” Zinc, copper, and iron are important for skin health and may help diagnose skin diseases.
January 2024 in “Journal of tissue engineering” Sunlight exposure damages hair follicles, but certain stem cell-derived particles can reduce this damage and help with hair regeneration.
December 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” AP-2α and AP-2β proteins are essential for healthy adult skin and hair.
December 2019 in “Buletin de psihiatrie integrativă” Skin treatments can improve both skin health and emotional well-being, but they require careful management of patient expectations and potential addiction risks.
84 citations,
February 2015 in “Experimental Dermatology” PPARγ is crucial for skin health but can have both beneficial and harmful effects.
51 citations,
August 2013 in “Journal of Investigative Dermatology” Human skin cells can create new hair follicles when transplanted into mice.
34 citations,
November 2010 in “Development” Activating Notch in adult skin causes T cells and neural crest cells to gather, leading to skin issues.
24 citations,
April 2017 in “Journal of Investigative Dermatology” Age, smoking, and lower BMI increase facial wrinkles; men wrinkle more than women, except in old age; pale skin and certain hormonal factors can protect against wrinkles.
14 citations,
April 2022 in “Climacteric” Menopause causes dry skin, wrinkles, and hair changes, with hormone therapy helping but not recommended just for these issues.
13 citations,
October 2012 in “InTech eBooks” Nanocarriers could improve how drugs are delivered through the skin but require more research to overcome challenges and ensure safety.