research A Molecular Wound Response Program Associated With Regeneration Initiation in Planarians
Planarian regeneration begins with a specific gene activation caused by injury, essential for healing and tissue regrowth.
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research WNT10A Mutation Causes Ectodermal Dysplasia by Impairing Progenitor Cell Proliferation and KLF4-Mediated Differentiation
A WNT10A gene mutation leads to ectodermal dysplasia by disrupting cell growth and differentiation.
research What Causes Hidradenitis Suppurativa?—15 Years After
Hidradenitis suppurativa is caused by genetic factors, inflammation, bacteria, hormones, and lifestyle factors like obesity and smoking.
research The Cycling Hair Follicle as an Ideal Systems Biology Research Model
The hair follicle is a great model for research to improve hair growth treatments.
research Cashmere Growth Control in Liaoning Cashmere Goat by Ovarian Carcinoma Immunoreactive Antigen-Like Protein 2 and Decorin Genes
OCIAD2 and DCN genes affect hair growth in goats by having opposite effects on a growth signaling pathway and inhibiting each other.
research A Guide for Building Biological Pathways with Two Case Studies: Hair and Breast Development
The document explains how to create detailed biological pathways using genomic data and tools, with examples of hair and breast development.
research TCM Medicine and Food Homology in the Management of Post-COVID Disorders
Traditional Chinese medicinal foods may help manage long-term post-COVID symptoms.
research Expression and Function of FGF5 Isoform in Hair Growth
Different forms of FGF5 either promote or inhibit hair growth.
research Tfap2b Specifies an Embryonic Melanocyte Stem Cell That Retains Adult Multi-Fate Potential
The gene Tfap2b is essential for creating a type of stem cell in zebrafish that can become different pigment cells.
research A Conditioned Medium of Umbilical Cord Mesenchymal Stem Cells Overexpressing Wnt7a Promotes Wound Repair and Regeneration of Hair Follicles in Mice
A special stem cell fluid can speed up wound healing and hair growth in mice.
research Keratin Expression by Corneal and Limbal Stem Cells During Development
Different types of cells in the eye express specific keratins at various stages of development.
research Dynamic Expression of Ornithine Decarboxylase in Hair Growth
The study investigated the role of ornithine decarboxylase (ODC) in hair follicles, revealing its importance in hair growth and follicle development. ODC, essential for polyamine synthesis, was crucial for hair growth, as its inhibition resulted in decreased hair growth and alopecia in various animals. The research showed that ODC expression was significant during the anagen phase of the hair cycle, especially in the follicle bulb, but absent in the catagen and telogen phases. Additionally, ODC was linked to cell proliferation and was vital during embryonic follicle development, indicating its significant role in hair follicle function and hair growth processes.
research Regulation of Stem Cell Fate by HSPGs: Implication in Hair Follicle Cycling
HSPGs help control stem cell behavior, affecting hair growth and offering a target for hair loss treatments.
research TLR9 Activation in Large Wound Induces Tissue Repair and Hair Follicle Regeneration via γδT Cells
Activating TLR9 helps heal wounds and regrow hair by using specific immune cells.
research Nanotechnology-Based Techniques for Hair Follicle Regeneration
Nanotechnology could improve hair regrowth but faces challenges like complexity and safety concerns.
research Matrisomal Components Involved in Regenerative Wound Healing in Axolotl and Acomys: Implications for Biomaterial Development
Certain genes are more active during wound healing in axolotl and Acomys, which could help develop materials that improve human wound healing and regeneration.
research Gab1 and MAPK Signaling Are Essential in the Hair Cycle and Hair Follicle Stem Cell Quiescence
Gab1 protein is crucial for hair growth and stem cell renewal, and Mapk signaling helps maintain these processes.
research A Pair of Transmembrane Receptors Essential for the Retention and Pigmentation of Hair
Bmpr2 and Acvr2a receptors are crucial for hair retention and color.
research Combined Effect of Microneedling and Platelet-Rich Plasma for the Treatment of Acne Scars: A Meta-Analysis
Using microneedling with platelet-rich plasma is more effective and just as safe as microneedling alone for treating acne scars.
research Local Microenvironment Provides Important Cues for Cell Differentiation in Lingual Epithelia
The local environment is crucial for cell development in the tongue.
research Miz1 Is Required for Hair Follicle Structure and Hair Morphogenesis
Miz1 is essential for proper hair structure and growth.
research Number Changes and Development Potential of Wool Follicle Cells in the Early Stages of Fiber Differentiation
Wool follicle cells are more complex than previously thought.
research Identification of Genes Related to Hair Follicle Cycle Development in Inner Mongolia Cashmere Goat by WGCNA
Researchers found genes linked to hair growth cycles in Inner Mongolia cashmere goats, which could help understand and treat hair loss.
research Hair Growth Effect and the Mechanisms of Rosa Rugosa Extract in DHT-Induced Alopecia Mice Model
Rosa rugosa extract promotes hair growth and could be a natural treatment for hair loss.
research Skin-Permeable Liposome Improved Stability and Permeability of bFGF Against Skin of Mice With Deep Second-Degree Scald to Promote Hair Follicle Neogenesis Through Inhibition of Scar Formation
A new liposome treatment helps heal deep burns on mice by improving hair regrowth and reducing scarring.
research The Striatin-Interacting Phosphatase And Kinases Complex Is Important for Skin Epidermal Differentiation and Barrier Formation
The STRIPAK complex is crucial for skin cell organization and creating a functional skin barrier.
research Intraoperative Bioprinting of Human Adipose-Derived Stem Cells and Extracellular Matrix Induces Hair Follicle-Like Downgrowths and Adipose Tissue Formation During Full-Thickness Craniomaxillofacial Skin Reconstruction
Printing human stem cells and a special matrix during surgery can help grow new skin and hair-like structures in rats.
research Engineered Skin Substitute Regenerates Skin with Hair Follicle Formation
The engineered skin substitute helped grow skin with hair on mice.
research Transgenic Erythropoietin Overexpression Inhibits Dermal Fat Formation and HIF1a in the Skin and Causes Telogen Effluvium in Mouse Pups During the First Hair Cycle
Erythropoietin overexpression disrupts hair growth and fat formation in mice.
research A Simple In Vivo System for Studying Epithelialization, Hair Follicle Formation, and Invasion Using Primary Epidermal Cells from Wild-Type and Transgenic Ornithine Decarboxylase-Overexpressing Mouse Skin
The study introduced a tracheal xenotransplantation assay to investigate epithelialization, hair follicle formation, and tumorigenesis using primary epidermal cells from both wild-type and transgenic mice. It demonstrated that keratinocytes overexpressing ornithine decarboxylase (ODC) combined with v-Ha-ras infection became invasive and malignant, whereas those expressing only one of these factors did not. The assay was also effective for hair follicle reconstitution, with fresh keratinocytes and fibroblasts forming hair follicles more successfully than cultured cells. This system provided a controlled environment to explore keratinocyte physiology, gene expression, and hair follicle development, particularly when cell numbers were limited.