12 citations,
January 2021 in “Journal of Investigative Dermatology” Hair follicle studies suggest that maintaining telomere length could help treat hair loss and graying, but it's uncertain if mouse results apply to humans.
1 citations,
July 2016 in “Elsevier eBooks” Understanding skin structure and development helps diagnose and treat skin disorders.
1 citations,
April 2016 in “CRC Press eBooks” Skin aging reflects overall body aging and can indicate internal health conditions.
January 2024 in “Animals” Circular RNA ERCC6 helps activate stem cells important for cashmere goat hair growth by interacting with specific molecules in an m6A modification-dependent way.
January 2018 in “bioRxiv (Cold Spring Harbor Laboratory)” Researchers found key regions in the mouse hairless gene that control its activity in skin and brain cells, affecting hair follicle function.
829 citations,
May 2007 in “Nature” Hair follicles can regrow in wounded adult mouse skin using a process like embryo development.
277 citations,
July 2011 in “Journal of the Dermatology Nurses’ Association” The skin's layers protect, sense, and regulate the body's internal balance, but can be prone to cancer.
111 citations,
January 2007 in “Seminars in cell & developmental biology” Hair, teeth, and mammary glands develop similarly at first but use different genes later.
81 citations,
June 2014 in “Cold Spring Harbor perspectives in medicine” Skin has specialized touch receptors that can tell different sensations apart.
25 citations,
February 2013 in “The journal of investigative dermatology/Journal of investigative dermatology” Blocking SCD1 in the skin with XEN103 shrinks sebaceous glands in mice.
19 citations,
December 2016 in “PLOS ONE” Early-stage skin cells help regenerate hair follicles, with proteins SDF1, MMP3, biglycan, and LTBP1 playing key roles.
16 citations,
March 2021 in “Frontiers in cell and developmental biology” A new method using Y-27632 improves the growth and quality of human hair follicle stem cells for tissue engineering and therapy.
16 citations,
September 2020 in “Animals” circRNA-1926 helps goat stem cells turn into hair follicles by affecting miR-148a/b-3p and CDK19.
15 citations,
August 2006 in “Journal of Cutaneous Pathology” HIV-1 may cause increased stem cell death in hair follicles, leading to hair loss.
14 citations,
January 2011 in “Journal of Cutaneous Pathology” CK15 is not a reliable marker for stem cells in damaged hair follicles from patients with CCCA.
10 citations,
October 2016 in “Experimental Dermatology” Nail stem cells and Wnt signaling are important for fingertip regeneration but not sufficient for regenerating more complex limb structures.
6 citations,
June 2016 in “The anatomical record” Dogs have varying numbers of touch-sensitive Merkel cells in different skin areas, with most in the oral mucosa and facial skin, unrelated to age, sex, breed, or color.
3 citations,
May 2013 in “International journal of molecular sciences” Epidermal stem cells show promise for treating orthopedic injuries and diseases.
1 citations,
November 2018 in “bioRxiv (Cold Spring Harbor Laboratory)” Signals from skin cells controlled by Rac proteins help turn certain precursor cells into white fat cells.
October 2024 in “Aesthetic Plastic Surgery” Micrografts are a safe and effective treatment for hair loss in both men and women.
25 citations,
September 2006 in “Birth Defects Research” Different processes create patterns in skin and things like hair and feathers.
1 citations,
September 2023 in “Journal of Investigative Dermatology” Melatonin may protect hair follicle cells from damage caused by a chemotherapy drug.
375 citations,
July 2006 in “Journal of Investigative Dermatology” Stress can worsen skin and hair conditions by affecting the skin's immune response and hormone levels.
28 citations,
October 2019 in “Seminars in Cell & Developmental Biology” Hair can regrow in large wounds through a process similar to how hair forms in embryos, and understanding this could lead to new treatments for hair loss or scarring.
11 citations,
October 2017 in “Journal of Investigative Dermatology” Applying certain inhibitors to the skin can promote hair growth without harming cells.
6 citations,
July 2017 in “Biochemical and Biophysical Research Communications” The Hairless gene is crucial for hair cell development, affecting whether skin cells become hair or skin and oil gland cells.
37 citations,
March 2006 in “Regulatory Peptides” Mice skin has components that could help with hair growth and might be used for diabetes treatment.
27 citations,
May 2006 in “Biochemical and Biophysical Research Communications” Wnt-10b is important for starting hair growth and developing hair follicles.
13 citations,
November 2013 in “Journal of Endocrinology/Journal of endocrinology” Vitamin D receptor helps control hair growth genes in skin cells.
22 citations,
October 2012 in “Cell Transplantation” Cells treated with Wnt-10b can grow hair after being transplanted into mice.