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Pig skin is a good substitute for human skin to measure drug absorption, but differences in skin structure and enzymes across species must be considered.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Skin development in mammals is controlled by key proteins and signals from underlying cells, involving stem cells for maintenance and repair.

Activating Nrf2 in skin cells causes skin disease similar to chloracne in mice.

Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.

Multiphoton microscopy is a promising tool for detailed skin imaging and could improve patient care if its challenges are addressed.

Microneedle arrays with nanotechnology show promise for painless drug delivery through the skin but need more research on safety and effectiveness.

Herbal nano-formulations show potential for effective skin delivery but need more research.

A new skin-whitening agent using a peptide from wheat is safe and effective at reducing skin pigmentation.

The model better predicts how water-loving and fat-loving substances move through the skin by including tiny pores and hair follicle paths.

Ethosomes improve drug delivery through the skin but may have side effects like irritation.

Nanoemulsions improve stability and delivery of active ingredients in cosmetics for skin and hair care.

Researchers identified specific genes that are important for mouse skin cell development and healing.

The document suggests that blocking sweat glands with antiperspirants might allow skin-generated hormones to be absorbed, possibly increasing breast and prostate cancer risk.

New treatments like nanotechnology show promise in improving skin cancer therapy.

Lipid-coated silica nanoparticles penetrate human skin more deeply than bare silica nanoparticles.

Niosomes are a promising and effective way to deliver drugs through the skin.

Lecithin-based microparticles can deliver minoxidil for hair growth effectively with less skin irritation.

Adding TPGS to minoxidil solutions can improve skin penetration and retention, especially in water and PEG 400-based solutions.

The flutamide-loaded hydrogel is a promising, skin-friendly treatment for acne and hair loss, potentially requiring less frequent application.

Hair follicles help substances penetrate the skin faster and more effectively.

Blocking YAP/TAZ could be a new way to treat skin cancer.

Improving how drugs are absorbed through the skin could better treat mange in wombats.

Spin traps like PBN could protect skin from pollution and sunlight in cosmetics but need more research for safe use.

Confocal Laser Scanning Microscopy (CLSM) is a useful tool for studying how drugs interact with skin and diagnosing skin disorders, despite some limitations.

Melanocytes are important for skin and hair color and protect the skin from UV damage.

Skin stem cells remember past inflammation, helping them respond better to future injuries and possibly aiding in treating skin issues.

3D imaging of skin biopsies offers better accuracy but is time-consuming and can't clear melanin.

Skin cell types develop when specific genes are turned on by removing certain chemical tags from DNA.

Type 3 Innate Lymphoid Cells help maintain skin health and balance, and are involved in skin diseases and healing.