research Dietary Fat- and Obesity-Sensitive Dermal Adipocyte PKCβ Induction and Inflammation Cross-Talk
Eating a lot of fat increases PKCβ and inflammation in skin fat cells, which affects skin and hair health.
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research Development of an Intrinsic Skin Sensor for Blood Glucose Level with CRISPR-Mediated Genome Editing in Epidermal Stem Cells
Researchers created a skin graft that senses blood glucose and could treat diabetes using CRISPR-edited stem cells.
research Recurrence of Pemphigus Vulgaris Associated With Interleukin 2 Therapy
A man's skin condition, pemphigus vulgaris, came back after he was treated with interleukin 2 for cancer.
research High Frequency of Cutaneous Manifestations Including Vitiligo and Alopecia Areata in a Prospective Cohort of Patients with Chronic Graft-Versus-Host Disease
Patients with chronic graft-versus-host disease often have skin problems like vitiligo and alopecia areata.
research Mutation-Specific siRNA Knockdown of GJB2: Potential Gene Therapy for Keratitis-Ichthyosis-Deafness Syndrome
Targeted siRNA therapy may be a promising treatment for KID syndrome by reducing mutant gene expression and improving cell communication.
research New Insights Into Inflammatory Memory of Epidermal Stem Cells
Skin stem cells remember past inflammation, helping them respond better to future injuries and possibly aiding in treating skin issues.
research The Spectrum of Inflammatory Skin Disease Following Jejuno-Ileal Bypass for Morbid Obesity
Some patients developed skin inflammation after obesity surgery, and a medication called dapsone helped treat it.
research Treating Resistant Cases of Alopecia Universalis
Combining platelet-rich plasma therapy with prostaglandin-F eye drops can significantly regrow hair in alopecia universalis.
research Structural and Biochemical Changes Underlying a Keratoderma-Like Phenotype in Mice Lacking Suprabasal AP1 Transcription Factor Function
Inhibiting AP1 in mice skin causes structural changes and weakens the skin barrier.
research Book Reviews
The document suggests "Occupational Skin Disease" is a useful standard text, finds "The Clinical Management of Itching" poorly organized, recommends "Atlas of Contact Dermatitis" for its illustrations, and values "Handbook of Diseases of the Hair and Scalp" for its information despite flaws.
research Helicobacter Pylori Infection and Skin Disorders
Some skin disorders might be linked to H. pylori infection, but more research is needed to confirm this.
research Stabilizing Mutations of KLHL24 Ubiquitin Ligase Cause Loss of Keratin 14 and Human Skin Fragility
Certain mutations in the KLHL24 gene cause a skin disorder by breaking down an important skin protein.
research Telogen Effluvium
Telogen effluvium is a hair loss condition that can be treated with medications like minoxidil.
research Exosomes In Dermatological Research: Unveiling Their Multifaceted Role In Cellular Communication, Healing, And Disease Modulation
Exosomes could help treat skin and hair issues by improving healing and reducing stress.
research Janus Kinase (JAK) Inhibitors for the Treatment of Skin and Hair Disorders: A Review of Literature
JAK inhibitors show promise for treating skin and hair disorders but need more research on long-term safety and effectiveness.
research Recent Advances in Congenital Ichthyoses
New genes linked to ichthyosis were found, but there's still no cure; treatment options are improving.
research Skin Steroidogenesis in Health and Disease
The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.
research Hidradenitis Suppurativa Treated With Finasteride
Finasteride effectively treats hidradenitis suppurativa for most patients.
research Molecular Heterogeneity of Quiescent Melanocyte Stem Cells Revealed by Single-Cell RNA-Sequencing
Different types of resting melanocyte stem cells have unique characteristics and vary in their potential to become other cells.
research Comparison Treatment of Vitiligo by Co-Culture of Melanocytes Derived from Hair Follicle with Adipose-Derived Stem Cells with and without Narrowband UVB
Treating vitiligo with stem cells and melanocytes from hair, along with UVB light, works better than without the light.
research 30% Supramolecular Salicylic Acid in the Treatment of Mild to Moderate Acne Vulgaris on the Face: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
30% supramolecular salicylic acid is safe and effective for treating mild to moderate facial acne.
research Phenotypic Heterogeneity of Epidermolysis Bullosa Associated With the Recurrent Pathogenic Variant p.(Arg2000Trp) in Plectin
The specific skin disease variant p.(Arg2000Trp) in plectin can cause a wide range of symptoms, which should be considered when diagnosing patients.
research Diagnostic Approach to the Pruritic Cat
Finding the cause of a cat's itchiness requires a careful process and good communication with the owner.
research Blood Plasma Levels of Heart Disease Biomarker Cardiac Troponin I Are Significantly Increased in Alopecia Areata Affected Individuals
People with alopecia areata have higher levels of a heart disease marker in their blood.
research Spectrum Changes of Pediatric Dermatological Disorders Before and During the COVID-19 Pandemic in China: A Single National Center for Children's Health Experience
During the COVID-19 pandemic in China, skin conditions like eczema and warts increased among children, while respiratory-transmitted skin infections decreased, partly due to mask-wearing.
research Anti-TNF Antibody-Induced Psoriasiform Skin Lesions in Patients with Inflammatory Bowel Disease Are Characterised by Interferon-γ-Expressing Th1 Cells and IL-17A/IL-22-Expressing Th17 Cells and Respond to Anti-IL-12/IL-23 Antibody Treatment
Anti-IL-12/IL-23 antibody therapy effectively treats psoriasiform skin lesions in IBD patients.
research A Link Between Psychiatric Disorders and Non-Scarring Alopecias: A Systematic Review
People with hair loss conditions often have more mental health issues like depression and anxiety compared to those without hair loss.
research Scalp Capillarectasia as a Trichoscopic Sign of COVID-19-Associated Telogen Effluvium
Dilated scalp capillaries might be a sign of hair loss related to COVID-19.
research Small Molecule Inhibitors and Inflammatory Skin Diseases
New drugs targeting the JAK-STAT pathway show promise for treating inflammatory skin diseases.
research Study of Pediatric Dermatology Consultations During COVID-19 Lockdown
Most child skin problems during the COVID-19 lockdown were not emergencies and could have been handled by teleconsultation.