November 2025 in “SHILAP Revista de lepidopterología” This review systematically evaluates 13 animal and 2 mathematical models for alopecia areata, assessing their effectiveness in understanding the condition's pathogenesis and aiding in the development of new therapeutic strategies.
November 2025 in “The Journal of Immunology” In a murine model of alopecia areata, this study observed that the IL-2 fusion protein HCW9302 helped prevent disease development by expanding regulatory T cells and reducing disease-causing effector T cell infiltrates, suggesting potential for using IL-2 fusion proteins in alopecia areata treatment.
May 2025 in “OPAL (Open@LaTrobe) (La Trobe University)” In this study, researchers analyzed the skin transcriptomes of Jiangnan cashmere goats and Changthangi pashmina goats, identifying 4,942 differentially expressed genes involved in pathways affecting cashmere quality, which could inform future genetic improvements in cashmere goat breeding.
This study found that activation of delta-opioid receptors in keratinocytes may delay the expression of the PER2 gene, suggesting a possible link to cancer development through circadian rhythm disruption.
October 2023 in “Bioactive Materials” This study developed a novel liposome-based delivery system for Minoxidil and nitric oxide, which showed promising results in promoting hair regrowth in an androgenetic alopecia model by enhancing transdermal absorption, prolonging skin retention, and reducing inflammation.
July 2023 in “International Journal of Cosmetic Science” This article reviews how biopolymers are utilized in cosmetics, highlighting their biodegradable and non-toxic properties, recent structural developments, novel applications, and safety considerations in the formulation of skin, hair, and oral care products.
June 2023 in “Skin Health and Disease” This editorial highlights recent progress in understanding chronic inflammatory skin diseases, leading to new treatments like JAK inhibitors for eczema and psoriasis, while emphasizing the journal's call for research on skin biology and aging.
This study found that selectively inactivating ribonucleotide excision repair in mouse epidermis leads to DNA damage, keratinocyte intraepithelial neoplasia, and squamous cell carcinoma, indicating a potential tumor-promoting mechanism related to compromised genome maintenance.
November 2022 in “Journal of the Endocrine Society” This case study highlighted that excessive iodide intake from the supplement TauriNac was associated with the development of hypothyroidism in a cystic fibrosis patient, which reversed upon discontinuation.
July 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” In this study, the researchers reported that Krox20 plays a crucial role in epidermal homeostasis and hair development, influencing stem cell maintenance and cell survival through the modulation of cellular pathways.