Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

In this study, researchers established that increased expression of the human GLI-1 gene in mouse skin leads to the development of tumors that closely resemble human basal cell carcinomas, without requiring additional mutations in the p53 or Ha ras genes.

This study reports that human hair follicle stem cells express different surface markers than mouse stem cells, facilitating their isolation and potentially aiding in the development of cell-based skin treatments.

This review discusses recent advancements in 3D bioprinting for skin regeneration and describes potential improvements for clinical applications, but it reports no new experimental results.

In this study, researchers found that human fingerprint ridges are formed through a modified hair follicle developmental process and spatial patterns influenced by specific signaling pathways.

This study demonstrated that the highly divergent WDSV rv-cyclin significantly stimulates eukaryotic cell proliferation, leading to hyperplastic skin lesions in transgenic mice.

Skin organ culture helps us understand skin biology and diseases better.

This study observed that earlier-passage keratinocyte cultures led to superior hair follicle neogenesis in dermal-epidermal composites grafted onto immunodeficient mice, suggesting their potential utility in studying human hair follicle development.

This review highlights advancements in 3D bioprinting for skin tissue engineering, focusing on exosome-loaded bioinks that show potential for enhancing skin regeneration and repair.

This study suggests that ferrous ferric chloride plays a role in regulating skin homeostasis by promoting the proliferation and differentiation of skin cells from a distance.

This article discusses the complexity of developing treatments for skin diseases due to their multifactorial pathogenesis and reports no new experimental results.

This article reviews how epigenetic modifications, particularly DNA methylation, histone modification, and non-coding RNA pathways, affect the development of skin diseases, suggesting potential for personalized treatments that target these changes.

This chapter discusses various skin functions and structures involved in protection, immune response, and homeostasis, but it reports no new research findings.

This study found that transgenic expression of COX-2 in mouse basal keratinocytes causes epidermal hyperplasia and certain dysplastic features at specific body sites.

This review discusses the recent advancements in understanding how keratins influence cytoarchitecture, cell dynamics, and disease processes but reports no new clinical results; the authors highlight its roles in development and diseases like cancer.

This study observed that vitamin D receptor knockout mice exhibit impaired epidermal differentiation and progressive hair loss, suggesting the importance of the vitamin D receptor in normal skin and hair follicle development.

This review discusses the use of mushrooms and their bioactive compounds in cosmeceuticals and nutricosmetics and reports no new clinical findings, highlighting potential areas for future research and development.

This article reviews key questions in skin biology, particularly the mechanisms of hair follicle patterning and the role of stem cells in the epidermis, reporting no new results.

This review discusses advances in skin tissue engineering, focusing on scaffold-free approaches and the application of stem cells, and reports no new research findings.

In this study, hydroxychloroquine use was associated with a delayed onset of integument damage in SLE patients, while higher disease activity over time predicted quicker damage development.

This review compiled by the authors emphasizes the traditional use of medicinal plants for dermatological disorders in India, highlighting the need for further scientific studies to validate their effectiveness and suggesting potential for drug development based on ethnodermatological practices.

This review discusses the role of the skin microbiome in the pathogenesis of various skin disorders, such as atopic dermatitis and psoriasis, and reports no new clinical findings; it emphasizes potential therapeutic implications.

This review discusses the mechanisms behind alopecia areata and primary cicatricial alopecia and reports no new clinical results, aiming to guide the development of targeted treatments.

This study observed that patients with CYLD mutations frequently experienced severe, painful tumors beyond the head and neck, impacting their quality of life, with hormonal factors possibly contributing to tumor development.

This article reviews the potential of nanoparticles for drug delivery through the skin barrier and highlights the need for further research on solid nanoparticles, as they lack commercial development for this purpose.

This study reported a 2.6% prevalence of myositis in patients with systemic lupus erythematosus, with alopecia, leukopenia, and active disease significantly associated with its development.

In this study using mice with specific gene knockouts, both farnesyltransferase and geranylgeranyltransferase-I were found to be essential for the proliferation and survival of skin keratinocytes.

This study presented a new two-dimensional model that successfully predicts transdermal permeation of caffeine, highlighting the significant role of the follicular pathway in increasing systemic bioavailability.

In this study, researchers found that microRNAs in the oar-let-7 and oar-miR-200 families were significantly up-regulated during critical fetal periods of cashmere goat hair follicle development, suggesting their role in this process.

This article reviews the causes and clinical presentation of pseudofolliculitis barbae, highlighting how genetic susceptibility and hair removal practices contribute to its development, but reports no new research findings.

This study found that azelaic acid entrapped in transethosomes exhibited enhanced antidermatophyte activity and improved treatment outcomes in guinea pig models of dermatophytosis compared to free azelaic acid.