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    Glossary Skin Development

    process by which skin forms and matures from embryonic stages

    Skin development refers to the process by which the skin forms and matures from embryonic stages through to adulthood. This involves the differentiation of various cell types, such as keratinocytes, melanocytes, and fibroblasts, and the formation of distinct layers like the epidermis, dermis, and hypodermis. Proper skin development is crucial for creating a functional barrier that protects the body from environmental hazards and regulates temperature and hydration.

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    1. Wnt Signaling in Skin Development, Homeostasis, and Disease Cold Spring Harbor Perspectives in Biology · 2012 · 260 citations
    2. Apoptosis in human skin development: Morphogenesis, periderm, and stem cells Developmental dynamics · 1994 · 253 citations
    3. Skin Cell Heterogeneity in Development, Wound Healing, and Cancer Trends in cell biology · 2018 · 211 citations
    4. BMP signaling in the control of skin development and hair follicle growth Differentiation · 2004 · 165 citations
    5. The role of fibroblast growth factor receptor 2b in skin homeostasis and cancer development The EMBO Journal · 2007 · 125 citations
    6. MicroRNA/mRNA regulatory networks in the control of skin development and regeneration Cell Cycle · 2012 · 56 citations
    7. Adhesion Molecules in Skin Development: Morphogenesis of Feather and Hair<sup>a</sup> Annals of the New York Academy of Sciences · 1991 · 45 citations
    8. Dynamic interplay between IL-1 and WNT pathways in regulating dermal adipocyte lineage cells during skin development and wound regeneration Cell Reports · 2023 · 44 citations
    9. Skin organoids: A new human model for developmental and translational research Experimental Dermatology · 2021 · 31 citations
    10. MicroRNAs in the skin: role in development, homoeostasis and regeneration Clinical Science · 2017 · 31 citations
    11. Pmg-1 and Pmg-2 constitute a novel family of KAP genes differentially expressed during skin and mammary gland development Mechanisms of Development · 1999 · 22 citations
    12. Foxn1 in Skin Development, Homeostasis and Wound Healing International Journal of Molecular Sciences · 2018 · 21 citations
    13. Skin Development and Disease: A Molecular Perspective Current Issues in Molecular Biology · 2024 · 15 citations
    14. Developmentally programmed early-age skin localization of iNKT cells supports local tissue development and homeostasis Nature Immunology · 2023 · 14 citations
    15. Hair follicle stem cell progeny heal blisters while pausing skin development EMBO reports · 2021 · 10 citations
    16. Genetic Tools for Cell Lineage Tracing and Profiling Developmental Trajectories in the Skin Journal of Investigative Dermatology · 2024 · 6 citations
    17. Skin development in the gray short‐tailed opossum (<i>Monodelphis domestica</i>)—From skin respiration to thermoregulation Journal of Anatomy · 2025 · 1 citations
    18. Integrative Analysis of the Metabolome and Transcriptome Reveals the Mechanism Underlying Differences in Skin Development Between the New Zealand Rabbit and the Rex Rabbit Animals · 2026
    19. 768 Dermal fibroblast expression of lef1 is critical to normal skin and hair development and regenerative wound healing in mice Journal of Investigative Dermatology · 2022
    20. Dermal EZH2 simultaneously orchestrates Wnt/β-catenin signaling dependent dermal differentiation and retinoic acid signaling dependent epidermal proliferation during murine skin development bioRxiv (Cold Spring Harbor Laboratory) · 2020
    21. Hair follicle stem cell progeny heal blisters while pausing skin development bioRxiv (Cold Spring Harbor Laboratory) · 2020
    22. Expression patterns of TRα and CRABPII genes in Chinese cashmere goat skin during prenatal development 2015
    23. A transgenic mouse model to study the role of epidermal growth factor (EGF) in hair and skin development 2002
    24. 1365 Elf5, a novel regulator of skin stem/progenitor cells fate during skin development? 2023
    25. 1439 Development of a complex skin organ in human induced pluripotent stem cell-derived organoids 2023
    26. Wnt target gene Ascl4 is dispensable for skin appendage development bioRxiv (Cold Spring Harbor Laboratory) · 2024
    27. The role of Kindlin-1 in skin homeostasis and tumor development Max Planck Digital Library · 2014
    28. Skin melanocytes: biology and development Postepy Dermatologii I Alergologii · 2013 · 401 citations
    29. 476 Development of an intrinsic skin sensor for blood glucose level with CRISPR-mediated genome editing in epidermal stem cells Journal of Investigative Dermatology · 2017
    30. Scratching the surface of skin development Nature · 2007 · 788 citations