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This review discusses the roles of dermal white adipose tissue in skin functions and pathology, underscoring its antibacterial activity and potential anti-fibrotic role, but reports no new experimental results.

In this study, researchers identified the antimicrobial peptide dermcidin in sebocyte lipid droplets, challenging the previous understanding of dermcidin as exclusively sweat-specific.

This study found that sulforaphane-rich broccoli sprout extracts reduced UV-induced erythema by 37.7% in humans, suggesting a protective strategy against UVR damage.

This review synthesizes existing research on the multilayered defense system of the skin, highlighting how physical, chemical, immune, and microbial barriers work together to maintain skin health, with disruptions in one often leading to broader barrier dysfunctions.

This study found that psoriatic skin lesions commonly express the cytokines IL-6, IL-8, and TNF-alpha along with a moderate presence of the antimicrobial protein defensin.

This review discusses dermal white adipose tissue's roles in skin immunity, highlighting its antimicrobial function and interactions with other immune cells, but reports no new clinical results.

This study found that nobiletin-loaded vesicles effectively restored skin condition in a mouse model of skin cancer, suggesting they are a promising treatment delivery system.

This study investigated pangolin skin genetics, finding that while sweat gland-related genes are not inactivated, several genes related to sebaceous gland function are, which highlights complex evolutionary adaptations in mammalian skin.

This study reviews melatonin's diverse roles in dermatology, highlighting its potential to protect skin from UV damage and oxidative stress, enhance DNA repair, and influence hair follicle cycling, suggesting therapeutic applications in skin care and hair renewal.

This study found that in obese mice, local antimicrobial activity is reduced due to a loss of adipogenic stem cells and an increase in mature adipocytes, leading to higher susceptibility to skin infections.

This study found that red ginseng extract may stimulate hair growth in a mouse model by enhancing dermal papilla cell proliferation and activating skin antioxidant defenses.

This review discusses the roles of human tissue kallikreins in skin physiology and pathology and reports no new findings, emphasizing their potential involvement in various skin functions and conditions.

This review discusses the role of defensin peptides in stem cell activation for potential skin rejuvenation therapies and reports no new clinical findings, emphasizing the need for further studies.

This article reviews the anatomy and pathology of skin and hair to aid in diagnosing skin diseases and discusses potential therapies, without reporting new clinical results.

The authors report that topical skincare products containing Coenzyme Q10 can replenish CoQ10 levels, enhance skin's energy metabolism, and reduce the depth of wrinkles by providing antioxidant effects, which may help reverse signs of aging related to oxidative stress.

Genetic factors affecting skin health and body weight may increase the risk of dermatophytosis.

This review found that intermittent fasting might benefit skin health by enhancing skin regeneration, delaying aging, and improving inflammatory skin conditions; however, most evidence is based on preclinical data, indicating a need for more human trials to confirm these findings.

This review summarizes major surveys on Behcet's disease, highlighting its systemic manifestations, with primary morbidity linked to ocular involvement causing severe vision loss or blindness.

This review discusses how acute exposures to environmental and internal stressors can quickly alter skin functions, leading to various dermatological symptoms, and calls for more research on these short-term effects.

This study explored the molecular biology of skin adaptations in pangolins, revealing that certain genes for lipid synthesis have inactive patterns, while others related to skin function remain intact, suggesting complex evolutionary changes in their skin physiology.

This article reviews the role of EGFR in human skin, focusing on the skin-related side effects of anti-EGFR cancer therapies, and reports no new clinical results.

This study using a genetic mouse model found that S. aureus-driven dysbiosis sustains inflammatory skin side effects from EGFR inhibitors, suggesting prophylactic antibiotic treatment may reduce rash severity without fixing barrier defects.

This symposium review highlights past, present, and future developments in skin research, celebrating the work of Prof. Johanna Brandner and Dr. Peter Arne Gerber, without reporting new clinical results.

Inhibiting EGFR weakens skin's defense against bacteria.

This study reports that keratinocytes grown under low oxygen conditions (physioxia) demonstrated reduced reactive oxygen species production and increased antioxidant enzyme activity compared to those in higher oxygen conditions, highlighting the role of oxygen in regulating skin antioxidant defenses.

In this study, O. forskahlii seed oil was found to promote hair growth in rats and exhibit anti-aging effects on human skin cells by enhancing fibroblast proliferation and inhibiting inflammation and enzyme activity, indicating potential for cosmetic use.

This study found that Melamax®, originally developed as an eco-friendly hair dye, provides significant protection against ultraviolet-induced oxidative and inflammatory damage in keratinocytes by modulating gene expression and signaling pathways, highlighting its dual potential for cosmetic coloration and skin photoprotection.

In this study, researchers found that psoriasis patients with untreated lesions showed increased activation of defensins, matrix metalloproteinases, and neuropeptides, which may be stimulated by specific inflammation pathways.

This study found that hairless dog breeds have adapted to maintain normal body and core temperatures through structural changes like a thicker epidermis and the role of melanin in thermoregulation, with genetic mechanisms involving the FOXI3 gene governing hairlessness.

This study observed that extracellular matrix scaffold membranes performed less effectively in wound healing for aged mice compared to younger ones, with senescent SPP1+ macrophages potentially hindering epidermal and fibroblast repair abilities.