research Chymase Activities and Survival in Endotoxin-Induced Human Chymase Transgenic Mice
Mice with human chymase had a higher death rate when exposed to a toxin compared to normal mice.
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research Aggressive Squamous Carcinomas of the Scalp
Aggressive scalp squamous cell carcinomas have a high death rate and need early, strong treatment.
research Expression of Apoptosis-Related Genes in the Mouse Skin During the First Postnatal Catagen Stage, Focused on Localization of Bnip3L and Caspase-12
The research found changes in gene expression related to cell death in mouse skin that help understand hair follicle development and skin health.
research Transepidermal UV Radiation of Scalp Skin Ex Vivo Induces Hair Follicle Damage That Is Alleviated by Topical Treatment with Caffeine
Caffeine applied to the scalp can protect hair follicles from UV damage.
research Association of Society of Dermatology Hospitalist Institutions With Improved Outcomes in Medicare Beneficiaries Hospitalized for Skin Disease
Patients at dermatology specialist hospitals had lower death and readmission rates but higher treatment costs.
research The Roles of Activins in Repair Processes of the Skin and the Brain
Activin A helps heal skin wounds and protects the brain after injury.
research Testosterone Prevents Cutaneous Ischemia and Necrosis in Males Through Complementary Estrogenic and Androgenic Actions
Testosterone helps prevent skin damage in males by acting through both estrogen and androgen pathways.
research Assessment of the Effect of Ficus Carica Leaf Extract on B16F10 Melanoma Cancer Cells: The Roles of p53, Caspase-3, and Caspase-9 in Inducing Intrinsic Apoptosis Cascade
Ficus carica leaf extract may help treat melanoma by promoting cancer cell death without harming normal cells.
research Hair Follicles Employ a Two-Dimensional Healing Strategy to Repair Three-Dimensional Injuries
Hair follicles repair 3D injuries using a 2D healing process.
research ELL Facilitates RNA Polymerase II-Mediated Transcription of Human Epidermal Proliferation Genes
ELL is crucial for gene transcription related to skin cell growth.
research Epidermal Expression of Receptor for Advanced Glycation End Products (RAGE) Is Related to Inflammation and Apoptosis in Human Skin
Skin RAGE levels are linked to inflammation and cell death.
research Identification of Ultraviolet B Radiation-Induced MicroRNAs in Normal Human Dermal Papilla Cells
UVB radiation changes the levels of certain microRNAs in skin cells, which may affect cell survival and hair growth.
research Progressive Alopecia Reveals Decreasing Stem Cell Activation Probability During Aging of Mice with Epidermal Deletion of DNA Methyltransferase 1
Mice lacking a key DNA methylation enzyme in skin cells have a lower chance of activating stem cells necessary for hair growth, leading to progressive hair loss.
research Transcriptome Analysis of Frontal Fibrosing Alopecia Revealed Involvement of Immune Cells and Ferroptosis
The research suggests that immune cells and a specific type of cell death called ferroptosis are involved in Frontal fibrosis alopecia.
research Mechanism of TAp73 Inhibition by ΔNp63 and Structural Basis of p63/p73 Hetero-Tetramerization
ΔNp63α stops TAp73β from working in skin cancer by blocking its access to specific genes, not by directly interacting with it.
research Postoperative Radiotherapy for Cutaneous Squamous Cell Carcinoma in Patients With Microscopic Residual Disease
Radiotherapy is a good option when further surgery for skin cancer isn't preferred, but more research is needed to compare it with other methods.
research A Null Mutation in the Cystatin M/E Gene of Ichq Mice Causes Juvenile Lethality and Defects in Epidermal Cornification
A gene mutation in mice causes skin defects and early death.
research Cell Death Functions in Hair Follicle Regeneration
Proper cell death regulation is crucial for normal hair follicle regeneration and skin remodeling.
research Mesenchymal Stem Cells Paracrine Proteins From Three-Dimensional Dynamic Culture System Promoted Wound Healing in Third-Degree Burn Models
Mesenchymal stem cell proteins in a special gel improved healing of severe burns.
research Clionasterol-Rich Fraction of Caulerpa Racemosa Against Particulate Matter-Induced Skin Damage Via Inhibition of Oxidative Stress and Apoptosis-Related Signaling Pathway
A substance from Caulerpa racemosa seaweed may protect against skin damage caused by air pollution by reducing oxidative stress and cell death.
research Rash Morphology as a Predictor of COVID-19 Severity: A Systematic Review of the Cutaneous Manifestations of COVID-19
Certain types of rashes in COVID-19 patients may indicate more severe illness and higher risk of death.
research Ginsenoside CK Inhibits Androgenetic Alopecia by Regulating Wnt/Beta-Catenin and P53 Signaling Pathways in AGA Mice
Ginsenoside CK, found in Panax ginseng, can prevent hair loss by controlling certain growth pathways and promoting hair follicle development.
research Role of Human Skin Antimicrobial Peptides in Psoriasis
Inflammation in psoriasis may trigger antimicrobial peptides and cell death.
research Epidermis-Specific Ablation of Claudin-1 in Adult Mice Demonstrates the Essential Role of a Tight Junction Barrier in Skin Homeostasis
Claudin-1 is crucial for maintaining skin barrier and preventing inflammation.
research Towards A Free Radical Theory Of Graying: Melanocyte Apoptosis In The Aging Human Hair Follicle As An Indicator Of Oxidative Stress Induced Tissue Damage
Oxidative stress causes hair to gray by damaging and killing pigment cells.
research TCF/Lef1-Mediated Control of Lipid Metabolism Regulates Skin Barrier Function
TCF/Lef1 is essential for skin barrier function by regulating lipid metabolism.
research Hair Shaft Miniaturization Causes Stem Cell Depletion Through Mechanosensory Signals Mediated by a Piezo1-Calcium-TNF-α Axis
Hair thinning causes stem cell loss through a process involving Piezo1, calcium, and TNF-α.
research Skin Fragility, Diffuse Ecchymosis, and Blisters on a Yellowish Waxy Base
A woman's skin symptoms led to a diagnosis of systemic AL amyloidosis, but she died from sepsis shortly after.
research Clinical Snippets: Dermatological Studies and Findings
Glycerol may improve wound healing and prevent keloids, a device can measure itch intensity, male pattern baldness is highly heritable, and fumaric acid esters may work for psoriasis by causing cell death in T cells.
research Lasers for Dermatology and Skin Biology
Lasers have become precise tools in skin treatment and diagnosis, with ongoing advancements improving their effectiveness.