180 citations
,
January 2003 in “American Journal of Clinical Dermatology” This article reviews the effects of menopause on skin aging and suggests that hormone replacement therapy may help reverse some of these changes.
76 citations
,
May 2007 in “Menopause International” This review discusses the relationship between estrogen deficiency and skin aging in postmenopausal women, noting potential benefits of estrogen use on skin collagen and elasticity, but reports no new clinical results.
41 citations
,
October 2017 in “International Journal of Women's Dermatology” This review provides an overview of the physiologic skin changes during pregnancy but reports no new findings, emphasizing the need for physicians to distinguish between benign and potentially pathological conditions.
38 citations
,
February 2012 in “Supportive Care in Cancer” Skin problems like acne, dry skin, and nail and hair changes are common in patients taking EGFR inhibitors.
25 citations
,
November 2014 in “Ageing Research Reviews” This review discusses the mechanisms of skin aging, highlighting the roles of stem/progenitor cells, genetic and environmental factors, and suggests potential for cell-based therapies, but reports no new experimental findings.
22 citations
,
March 2017 in “Journal of the Formosan Medical Association” This report presents the Taiwanese Dermatological Association's 2016 consensus on defining and managing skin toxicities from EGFR-TKI treatments, providing comprehensive guidelines for clinicians in Taiwan.
19 citations
,
October 2008 in “Journal der Deutschen Dermatologischen Gesellschaft” This article reviews the cutaneous reactions and characteristic skin changes associated with chemotherapy, radiation therapy, and new targeted cancer treatments, reporting no new clinical results.
18 citations
,
August 2018 in “Facial Plastic Surgery Clinics of North America” This review summarizes the positive clinical response of using platelet-rich plasma as an adjuvant in skin rejuvenation treatments, with no identifiable complications, suggesting a promising outlook for its future use.
17 citations
,
February 2012 in “Cutaneous and Ocular Toxicology” This study found that xerosis and pruritus are prevalent in patients with chronic renal failure undergoing hemodialysis, highlighting the importance of early recognition of skin issues to alleviate discomfort and reduce complications.
14 citations
,
April 2022 in “Climacteric” This review discusses the impact of HRT on menopausal skin and hair symptoms and argues that potential benefits should be part of informed decision-making for managing menopause.
6 citations
,
September 2013 in “The Obstetrician & Gynaecologist” This article reviews the physiological skin changes and unique dermatoses in pregnancy, discussing their causes and management, but reports no new clinical findings.
4 citations
,
March 2002 in “Journal of the American Pharmaceutical Association” This review discusses various skin conditions affecting women throughout their lives and highlights the pharmacist's role in advising on management and treatment, but it reports no new clinical results.
3 citations
,
January 2019 in “Jikken doubutsu ihou/Jikken doubutsu/Experimental animals/Jikken Dobutsu” This study reported that knocking out the HR gene in pigs using CRISPR/Cas9 led to hairless eyelids and abnormalities in the thymus and peripheral blood, suggesting pigs as a model for human HR-related hair disorders.
research Skin
2 citations
,
January 2011 in “Elsevier eBooks” This review discusses approaches to diagnosing and managing cutaneous manifestations of lupus erythematosus and reports no new clinical results.
1 citations
,
February 2022 in “International Journal of Dermatology” This review discusses the persistence of certain cutaneous changes after pregnancy and highlights the need for further investigation when conditions like telogen effluvium, severe hirsutism, palmar erythema, and striae do not resolve as expected.
1 citations
,
May 2026 in “Nature Communications” This study demonstrated that CD19-CAR T cell therapy may promote structural regeneration in the skin of systemic sclerosis patients, as evidenced by histological improvements and fibroblast population changes, suggesting its potential for tissue remodeling in fibrotic diseases.
1 citations
,
January 2024 in “Microorganisms” This study suggests that the synthetic peptide SPIKENET (SPK) may protect against long-term skin alterations in mice following coronavirus infection, offering potential therapeutic intervention for similar effects in humans post-COVID-19.
1 citations
,
April 2016 in “CRC Press eBooks” Skin aging reflects overall body aging and can indicate internal health conditions.
August 2026 in “npj Biofilms and Microbiomes” In this study, researchers observed menopausal stage-specific differences in the prevalence and abundance of Malassezia species on the skin of 345 Asian women, linking menopause-driven skin changes to Malassezia-induced keratinocyte dysfunction and inflammation, which could contribute to dermatological diseases.
April 2026 in “Dermatology and Therapy” This review discusses the various skin changes, pregnancy-specific dermatoses, and medication management related to dermatologic health during pregnancy, aiming to provide clinicians with an evidence-based guide for diagnosis and treatment.
March 2026 in “International Journal of Health Science” In this narrative literature review, researchers found that physiological skin changes are extremely common during pregnancy due to hormonal and circulatory adaptations, emphasizing the need for healthcare professionals to recognize these changes to provide proper guidance to pregnant women and avoid unnecessary interventions.
January 2024 in “Cosmetics” In this study, Brazilian postmenopausal women reported that menopause significantly deteriorates the quality of their skin, nails, and hair, negatively affecting self-esteem and quality of life, with a need for better understanding of hormone replacement therapy's dermatological effects.
June 2023 in “International Journal of Research in Dermatology” In this study, obese patients who underwent bariatric surgery experienced significant weight loss, which was associated with improvements in certain skin conditions, such as intertrigo, tinea corporis, and striae rubra, although the prevalence of many other skin diseases remained unchanged.
July 2020 in “International Journal of Dermatology Venereology and Leprosy Sciences” In this study, dermatological changes were highly prevalent among postmenopausal women, with xerosis, pigmentary changes, and hair thinning being the most common findings, suggesting such changes are often overlooked in clinical practice.
Skin changes throughout life, from development before birth to aging effects like wrinkles, influenced by both genetics and environment.
108 citations
,
January 2003 in “Journal of Cosmetic Dermatology” This summary explains the different types of wrinkles, their causes, and their distinct microanatomical characteristics, noting that each type may respond differently to treatments.
78 citations
,
September 2008 in “International Journal of Cosmetic Science” This review outlines various clinical methods for assessing ageing skin and discusses their application in supporting the efficacy claims of anti-ageing treatments, but it reports no new clinical results.
11 citations
,
January 2013 in “Postępy Dermatologii i Alergologii” This review discusses various theories of skin aging and the importance of using professional and at-home skincare solutions, but offers no new empirical findings.
September 2015 in “Actas Dermo-Sifiliográficas” This review covers skin manifestations in chronic kidney disease, highlighting their impact on quality of life, associated prognostic indicators, and available treatments, but provides no new clinical results.
105 citations
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January 2010 in “Mediators of Inflammation” This article reviews the role of skin surface lipid in mediating environmental stressors and discusses potential therapeutic interventions, reporting no new experimental findings.