245 citations,
October 2015 in “Nature medicine” Hair follicle-derived IL-7 and IL-15 are crucial for maintaining skin-resident memory T cells and could be targeted for treating skin diseases and lymphoma.
19 citations,
September 2019 in “PLOS genetics” Telomere damage affects skin and hair follicle stem cells by messing up important growth signals.
October 2023 in “Cancers” Skin cancer in sun-exposed areas is more likely to come back.
60 citations,
June 2019 in “Ageing Research Reviews” Fat from the body can help improve hair growth and scars when used in skin treatments.
24 citations,
July 2018 in “Stem cells” Runx1 controls fat-related genes important for normal and cancer cell growth, affecting skin and hair cell behavior.
11 citations,
January 2017 in “Oxidative medicine and cellular longevity” Antroquinonol may help prevent skin depigmentation by suppressing certain immune cells.
144 citations,
September 2012 in “Genes & development” Aging causes skin stem cells to work less effectively.
57 citations,
March 2018 in “International Journal of Molecular Sciences” The extracellular matrix is crucial for controlling skin stem cell behavior and health.
12 citations,
August 2022 in “Biochemical Journal” Different types of cell death affect skin health and inflammation, and understanding them could improve treatments for skin diseases.
76 citations,
June 2018 in “EMBO Reports” YAP and TAZ proteins are necessary for the development of two types of skin cancer.
9 citations,
January 2015 in “Medical hypotheses” TCDD disrupts skin stem cells, causing skin issues like chloracne.
66 citations,
July 2015 in “Journal of Molecular Biology” The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.
19 citations,
April 2015 in “Developmental Dynamics” The conclusion is that skin and hair patterns are formed by a mix of cell activities, molecular signals, and environmental factors.
September 2023 in “Research Square (Research Square)” TNC+ fibroblasts play a key role in skin inflammation by interacting with T cells.
January 2015 in “Springer eBooks” Hormones affect skin aging, and treatments targeting hormonal balance may improve skin health.
38 citations,
September 2014 in “Cell and Tissue Research” The hair follicle infundibulum plays a key role in skin health and disease, and understanding it better could lead to new skin disease treatments.
31 citations,
July 2017 in “Clinical Science” MicroRNAs are important for skin health and could be targets for new skin disorder treatments.
6 citations,
December 2019 in “Frontiers in genetics” GLI1 might protect against the start of skin cancer and is not linked to cancer severity.
60 citations,
April 2012 in “Physiology” The document concludes that understanding hair and feather regeneration can help develop new regenerative medicine strategies.
45 citations,
March 2020 in “ACS Applied Materials & Interfaces” The new biomaterial inspired by ancient Chinese medicine effectively promotes hair growth and heals wounds in burned skin.
11 citations,
March 2020 in “Immunology” Human prenatal skin develops an immune network early on that helps with skin formation and healing without scarring.
7 citations,
September 2020 in “Frontiers in Cell and Developmental Biology” IL-36α helps grow new hair follicles and speeds up wound healing.
6 citations,
April 2010 in “Cellular Reprogramming” Pig skin cells can turn into mesodermal cells but lose their ability to become neural cells.
101 citations,
March 2019 in “Cell Stem Cell” Certain immune cells in the skin release a protein that stops hair growth by keeping hair stem cells inactive.
59 citations,
June 2022 in “Frontiers in medicine” There are still challenges in diagnosing and treating chronic skin diseases, but there is hope for future improvements.
1 citations,
July 2016 in “Elsevier eBooks” Understanding skin structure and development helps diagnose and treat skin disorders.
21 citations,
January 2003 in “Skin pharmacology and physiology” Different skin cells process testosterone differently, and certain drugs can change this process, possibly helping treat acne and hair loss.
11 citations,
February 2019 in “Stem cells international” Skin-derived stem cells grow faster and are easier to obtain than hair follicle stem cells, but both can become various cell types.
306 citations,
April 2019 in “International Journal of Molecular Sciences” The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.
222 citations,
January 2005 in “Endocrine journal” Melatonin is important for skin health and protection, and can be made by the skin or applied to it.