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Isotretinoin's effects and side effects, like birth defects and depression, might be due to it causing cell death in various cells.

Doctors need to be better prepared to assess and treat obesity in patients.

Using CRISPR for gene editing in the body is promising but needs better delivery methods to be more efficient and specific.

The document concludes that while there are various treatments for Alopecia Areata, there is no cure, and individualized treatment plans are essential due to varying effectiveness.

Multiple treatments work best for hair loss.

The document explains different types of hair loss, their causes, and treatments, and suggests future research areas.

Reduced AR gene methylation may cause early pubic hair growth in girls.

Botox increased hair count in men with baldness and might work by improving scalp blood flow.

Flutamide reduces hair growth better but has more side effects.

Different treatments for alopecia areata have varying success rates and side effects; intralesional steroids are most effective.

Taking DHEA for a year is generally safe for postmenopausal women but may cause acne and more facial hair without improving metabolism or aging.

Testosterone therapy can help improve sexual desire and function in postmenopausal women but may cause side effects and is not FDA-approved for this use.

Male hormones, or androgens, affect women's health in areas like mood and bone density, and hormone replacement therapy using antiandrogenic progestogens can improve mood disorders and alertness in menopausal women.

Stem cell therapy may help treat tough hair loss cases.

Human leukocytes and beard hair follicle cells have internal daily clocks, and PER1 and PER3 genes may indicate individual circadian rhythms.

Weight loss and metformin don't significantly change vaspin levels in women with PCOS.

The document suggests that clinical trials for PCOS should focus on meaningful primary outcomes like live birth rates, rather than less reliable surrogate markers.

5-alpha reductase inhibitors slightly increase the risk of sexual and mood side effects, and breast growth in men.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Testosterone therapy may slightly improve sexual function in postmenopausal women, but its long-term safety is unknown.

Men with common hair loss may have a higher risk of heart disease and diabetes, and should be checked for these conditions.

A team approach is crucial for managing PCOS, with dermatologists playing a key role.

New techniques in scalp reconstruction have improved cosmetic results and reduced complications, especially for large defects.

Birth control pills combined with bicalutamide are more effective at reducing excessive hair growth in women with PCOS than birth control pills alone.

Testosterone therapy aims to treat hormone deficiencies and various conditions safely and effectively, but requires careful patient monitoring due to potential side effects.

Men with early-onset baldness have a higher chance of heart disease and clogged arteries.

The hepatitis B vaccine did not cause hair loss in the tested mice.

HPV vaccines are generally safe but need further investigation for rare side effects.

Rice bran extract might help prevent hair loss.

Testosterone implants in women require pharmacological dosing to be effective and are generally safe and well-tolerated.