114 citations,
December 1951 in “Archives of Dermatology” Aminopterin strongly suppresses epithelial tissues and can treat certain skin conditions but has significant side effects.
252 citations,
April 2009 in “Seminars in Cell & Developmental Biology” The immune system plays a key role in tissue repair, affecting both healing quality and regenerative ability.
January 2024 in “Biotechnology advances” Bioassays help find useful compounds in nature for making medicines, supplements, and cosmetics.
April 2021 in “Journal of Investigative Dermatology” Bacteria can help skin regenerate through a process called IL-1β signaling.
26 citations,
June 2018 in “The journal of immunology/The Journal of immunology” AIRE-deficient rats developed severe autoimmune disease similar to APECED, useful for testing treatments.
9 citations,
August 2021 in “Experimental dermatology” Hidradenitis suppurativa is a skin disease caused by the breakdown of the skin's natural immune barriers, especially around hair follicles.
1 citations,
March 2023 in “Pharmaceutics” PBMCsec can help reduce and improve thick skin scars.
December 2015 in “아시안뷰티화장품학술지” Green tea's EGCG has various health benefits, including antioxidant properties, skin protection, cancer cell growth inhibition, anti-inflammatory effects, fat breakdown, detoxification, diabetes management, hair growth stimulation, and prevention of gum disease.
March 2002 in “Clin-Alert” In 2002, various drugs caused serious side effects, including vitamin B12 deficiency, heart issues, blindness, hypersexuality, allergic reactions, blood clotting problems, pupil dilation, capillary leak syndrome, muscle breakdown, hepatitis, skin reactions, and lupus.
124 citations,
June 2020 in “Cell Stem Cell” Fat cells in the skin help start healing and form important repair cells after injury.
65 citations,
January 2018 in “Nature Reviews Endocrinology” Skin fat has important roles in hair growth, skin repair, immune defense, and aging, and could be targeted for skin and hair treatments.
26 citations,
May 2016 in “Journal of biological chemistry/The Journal of biological chemistry” sPLA2-IIE is crucial for normal hair follicle structure and skin health.
15 citations,
March 2015 in “Experimental Dermatology” Clotrimazole, an antifungal cream, may safely reduce skin pigmentation by breaking down the enzyme needed for making melanin.
9 citations,
February 2014 in “Tissue Engineering and Regenerative Medicine” Conditioned media from human amniotic fluid-derived stem cells helps skin heal and protects against aging from sun exposure.
59 citations,
February 1998 in “Chemico-Biological Interactions” Minoxidil breakdown varies by enzymes, affecting hair loss treatment effectiveness.
13 citations,
January 2020 in “Scientific Reports” The African spiny mouse heals skin without scarring due to different protein activity compared to the common house mouse, which heals with scarring.
11 citations,
January 1977 in “Archives of dermatological research” Mouse tail skin has different keratinization near hair follicles and scales.
7 citations,
January 1991 in “Comparative biochemistry and physiology. A. Comparative physiology” A diet high in vitamin E improved blood health, skin, and fur in common marmosets.
Erythropoietin overexpression disrupts hair growth and fat formation in mice.
Cornification is the process where living skin cells die to create a protective barrier, and problems with it can cause skin diseases.
1 citations,
May 2017 in “Journal of The American Academy of Dermatology” The moisturizer with phytol improved skin texture and reduced fine wrinkles better than the moisturizer without it.
5 citations,
September 2018 in “International journal of genomics” Genetic mutations that disrupt homocysteine breakdown lead to increased damage in mouse hair keratin.
1 citations,
March 2019 in “Lasers in Surgery and Medicine” The conference reported improvements in muscle volume, skin cancer diagnosis, facial and vaginal rejuvenation, and hair growth using various laser treatments.
88 citations,
July 2001 in “British journal of dermatology/British journal of dermatology, Supplement” The method effectively measures lipid changes and drug effects on skin follicles.
April 2023 in “Journal of Investigative Dermatology” Aging changes skin cells, leading to different DNA methylation and gene activity, affecting cell metabolism and aging signs.
March 1993 in “Neuroscience letters” Biotin is important for metabolism, with specific daily intake recommendations, and deficiency can cause health problems.
September 1989 in “Neuroscience letters” People need different amounts of biotin based on age, and not getting enough can cause health problems.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” The study found that a key immune pathway protecting hair follicles is reduced in a mouse model of scarring hair loss.
The document discusses various diseases of the outer ear, categorized by symptoms like redness, crusts, bumps, pus-filled lesions, lumps, ulcers, and hair loss.
9 citations,
June 2020 in “Cell stem cell” Skinny fat cells help wounds heal faster by releasing fatty acids.