47 citations,
September 2015 in “Cell Cycle” Different skin stem cells help heal wounds, with hair follicle cells becoming more important over time.
8 citations,
July 2015 in “European journal of histochemistry” Sox9 is present in most canine skin tumors and may help understand stem cells' role in these cancers.
March 2021 in “Cell stem cell” Skin cell behavior is influenced by the tightness of nearby cells, affecting their growth and development.
105 citations,
October 2017 in “Stem cells” Wnt signaling is crucial for skin development and hair growth.
60 citations,
March 2011 in “Proceedings of the National Academy of Sciences of the United States of America” RANK-RANKL signaling is essential for hair growth and skin health.
1 citations,
January 2016 in “Elsevier eBooks” The document concludes that identifying the specific cells where skin cancers begin is important for creating better prevention, detection, and treatment methods.
85 citations,
September 2013 in “International Journal of Molecular Sciences” Keratin 15 is not a reliable sole marker for identifying epidermal stem cells because it's found in various cell types.
5 citations,
January 2019 in “Elsevier eBooks” Current therapies cannot fully regenerate adult skin without scars; more research is needed for scar-free healing.
November 2023 in “npj regenerative medicine” Skin spheroids with both outer and inner layers are key for regrowing skin patterns and hair.
1 citations,
June 2016 in “Yāftah/hā-yi nuvīn dar ̒ulūm-i zīstī” Sheep testis extract significantly improves wound healing and hair growth in rats.
18 citations,
January 2019 in “European journal of histochemistry” Cattle skin has leptin which might control skin and hair growth.
16 citations,
May 2011 in “The Journal of clinical investigation/The journal of clinical investigation” Some skin tumors may start from hair follicle stem cells.
127 citations,
July 2002 in “EMBO journal” Normal skin cell renewal doesn't need RAR signaling, but vitamin A-related skin thickening does.
1 citations,
June 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” Activating β-catenin in mammary cells leads to changes that cause early-stage abnormal growths similar to skin structures.
28 citations,
April 1996 in “Cell biology international” Changes in keratin affect skin health and can lead to skin disorders like blistering diseases and psoriasis.
April 2018 in “Journal of Investigative Dermatology” Kaempferol helps skin stem cells grow and may improve skin thickness due to its 3-OH group.
21 citations,
July 2006 in “Veterinary dermatology” CD34 marks potential stem cells in dog hair follicles.
2 citations,
December 2003 in “Medical electron microscopy” The skin and mucous membranes can regenerate over the basement membrane after damage, using nearby surviving cells.
35 citations,
June 2012 in “PloS one” Keratin 15 expression in skin cells is regulated by two mechanisms involving PKC/AP-1 and FOXM1.
Ovol2 is crucial for hair growth and skin healing by controlling cell movement and growth.
28 citations,
March 2010 in “Histochemistry and Cell Biology” Different markers are found in stem cells of the scalp's hair follicle bulge and the surrounding skin.
153 citations,
October 2007 in “Cell Stem Cell” New research suggests that skin cell renewal may not require a special type of cell previously thought to be essential.
April 2016 in “Journal of Investigative Dermatology” Full thickness wounds on Lanyu pigs' skin resulted in abnormal skin structure and function due to changes in molecular expression patterns.
January 2006 in “Elsevier eBooks” Most vertebrates can regenerate skin, nails, and corneas, but only some can regenerate teeth and lenses.
25 citations,
April 1949 in “The journal of experimental zoology” Testosterone applied to rabbit skin increases skin cell growth and changes skin structure.
2 citations,
February 2021 in “Developmental Cell” Middle-aged skin shows aging signs, and quercetin might help delay them.
9 citations,
May 2002 in “PubMed” Retinoic acid affects skin and hair health by working with specific receptors, and its absence can lead to hair loss and skin changes.
November 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” Ezh2 controls skin development by balancing signals for dermal and epidermal growth.
46 citations,
December 2018 in “Genes & Development” Lung repair involves both dedicated and flexible stem cells, important for developing new treatments.
April 2018 in “Journal of Investigative Dermatology” Nonmelanoma skin cancers have higher levels of certain osteopontin variants than normal skin.