40 citations,
January 2016 in “Elsevier eBooks” The skin is the largest organ, protecting the body, regulating temperature, and producing hormones.
2 citations,
November 2018 in “Cell Stem Cell” The research found a new way to heal chronic skin ulcers by turning certain cells into skin tissue using specific factors.
32 citations,
January 2022 in “International Journal of Molecular Sciences” Melatonin, a hormone, can help protect skin from aging by reducing stress, inflammation, and damage, and may also help treat hair loss in women.
9 citations,
May 2012 in “PLOS ONE” ILK is essential for skin development, pigmentation, and healing.
28 citations,
July 2007 in “Development” TAF4 is important for skin cell growth and helps prevent skin cancer in mice.
2 citations,
January 2023 in “Journal of toxicologic pathology” Skin structure complexity and variability are crucial for assessing skin toxicity in safety tests.
13 citations,
September 2012 in “Cell & tissue research/Cell and tissue research” pCLCA2 protein may help maintain skin structure and function.
62 citations,
November 2013 in “Journal of Human Evolution/Journal of human evolution” Forensic DNA Phenotyping can help predict physical traits from crime scene DNA to identify suspects.
36 citations,
December 2011 in “Journal of dermatological science” Human hair has a protective lipid layer that can be damaged by moisture and treatments, affecting hair growth and health.
12 citations,
February 2019 in “Skin research and technology” White hair has less lipid content and absorbs water differently than brown hair.
67 citations,
September 2007 in “American Journal of Pathology” Overexpressing the mineralocorticoid receptor in mouse skin causes skin thinning, early skin barrier development, eye issues, and hair loss.
156 citations,
November 2016 in “Journal of controlled release” Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.
38 citations,
September 2014 in “Cell and Tissue Research” The hair follicle infundibulum plays a key role in skin health and disease, and understanding it better could lead to new skin disease treatments.
12 citations,
February 2018 in “Food and chemical toxicology” Permanent hair dye mixtures can irritate and damage the skin.
147 citations,
November 2020 in “International Journal of Molecular Sciences” Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.
May 2023 in “Journal of Investigative Dermatology” LSD1 is essential for healthy skin development and creating the skin's protective barrier.
15 citations,
March 2014 in “Biochimica and biophysica acta. Molecular and cell biology of lipids” ACBP is essential for healthy skin and fur by maintaining the skin's barrier function.
June 2024 in “Journal of Allergy and Clinical Immunology” TSLP affects atopic dermatitis by increasing sebum and reducing fat through IL-4/IL-13 signaling.
52 citations,
December 2000 in “Archives of Dermatological Research” Scalp skin barrier affects hair loss; personalized treatments needed.
22 citations,
June 2013 in “International journal of molecular sciences” Stem cell differentiation is crucial for skin barrier maintenance and its disruption can lead to skin diseases.
16 citations,
September 2015 in “International Journal of Molecular Sciences” A specific gene variant causes severe skin issues and increases infection risk, requiring careful medical monitoring.
9 citations,
August 2021 in “International journal of molecular sciences” PPARγ is essential for maintaining healthy skin, controlling inflammation, and ensuring proper skin barrier function.
March 2015 in “Plastic and reconstructive surgery” Human skin has multiple layers and functions, with key roles in protection, temperature control, and appearance.
May 2018 in “Journal of Investigative Dermatology” Dsg1 is essential for maintaining a healthy skin barrier in mice.
8 citations,
July 2022 in “Biomedicines” Autophagy helps keep skin healthy and may improve treatments for skin diseases.
2 citations,
August 2020 in “Scientific reports” Genes related to keratin, skin cell differentiation, and immune functions are key in hedgehog skin and spine development.
23 citations,
December 2021 in “Frontiers in Immunology” IL-1 family cytokines are crucial for skin defense and healing, but their imbalance can cause skin diseases.
3 citations,
September 2005 in “Experimental dermatology” The cornified envelope is crucial for skin's barrier function and involves key proteins and genetic factors.
67 citations,
January 2022 in “Theranostics” Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.
Cornification is the process where living skin cells die to create a protective barrier, and problems with it can cause skin diseases.