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Human skin cells have a high-affinity system for biotin transport, crucial for skin health.

Three specific genetic variants cause severe skin issues in children with EBS, highlighting the need for early genetic screening.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

Cushing's syndrome can cause serious health problems, and early treatment is crucial, but some issues may remain after treatment.

Hydroxychloroquine may help delay skin damage in lupus patients.

Woodhouse-Sakati syndrome often causes sexual development issues, hair loss, learning disabilities, deafness, muscle contractions, limb pain, and diabetes.

The document concludes that ongoing research using animal models is crucial for better understanding and treating Alopecia Areata.

Mutations in NIPAL4 cause skin issues by disrupting lipid layers, but some improvement is seen with topical treatment.

The document concludes that fexofenadine reduces inflammation in chronic hives, cholestyramine helps half of pregnant women with itchy rashes, and relaxing incisions are a good alternative in facial surgery for the elderly.

Different genes are active in dogs' hair growth and skin, similar to humans, which helps understand dog skin and hair diseases and can relate to human conditions.

Deleting the Trf1 protein in mice is safe and may help prevent cancer without major side effects.

Stump-tailed macaque best for researching hair loss causes and treatments.

Tiny particles called extracellular vesicles show promise for treating skin conditions and promoting hair growth.

Retinoic acid affects skin and hair health by working with specific receptors, and its absence can lead to hair loss and skin changes.

Krt16-deficient mice help understand skin disorders like PC and FNEPPK.

Keratin helps skin cells mature when added to a collagen mix, which could be important for skin and hair health.

A girl with skin rashes and low zinc levels improved with zinc supplements and had new gene mutations linked to her condition.

The vitamin D receptor can act without its usual activating molecule, affecting hair growth and skin cancer, but its full range of actions is not well understood.

ZDHHC13 is important for normal liver function and metabolism, affecting mitochondrial activity.

The conclusion is that metformin is a first-line treatment for PCOS, particularly for restoring ovulation and increasing pregnancy rates, with other treatments depending on specific symptoms.

Topical vitamin D is effective in treating vitiligo with few side effects.

The Polish Dermatological Society recommends personalized treatment for cutaneous lupus, including lifestyle changes, medications, and monitoring, with specific drugs for severe cases.

Some children are born with unusually short, fine hair because their hair growth phase is short, but this often gets better by itself during puberty.

Human hair has a protective lipid layer that can be damaged by moisture and treatments, affecting hair growth and health.

Older patients with Cushing's syndrome often have different symptoms and treatment outcomes compared to younger patients.

A Shi Tzu dog with high cortisol levels improved after increasing the dose of trilostane.

Intu gene is crucial for hair follicle formation by helping keratinocytes differentiate through primary cilia.

Goats with BSE or scrapie show varying symptoms, and using only clinical signs may not detect all scrapie cases.

Both immature and mature fat cells are important for hair growth cycles, with immature cells promoting growth and mature cells possibly inhibiting it.