143 citations,
September 2008 in “Experimental gerontology” Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.
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October 2004 in “Anesthesiology” Preoperative pain assessment, regional anesthesia, and vitamin C can help prevent CRPS after surgery.
94 citations,
June 2016 in “The FASEB Journal” The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.
81 citations,
July 2008 in “The Journal of Clinical Endocrinology and Metabolism” Certain mutations in the H6PD gene cause Cortisone Reductase Deficiency by affecting hormone production.
70 citations,
August 2020 in “Nanomaterials” Electrospun nanofibers show promise for enhancing blood vessel growth in tissue engineering but need further research to improve their effectiveness.
68 citations,
September 2018 in “Trends in Cell Biology” Cancer can hijack the body's cell repair system to promote tumor growth, and targeting this process may improve cancer treatments.
61 citations,
February 2001 in “American Journal of Obstetrics and Gynecology” Metabolic syndrome and PCOS are related but separate conditions, with metabolic syndrome increasing the risk of heart disease and diabetes.
60 citations,
May 2011 in “Endocrinology and Metabolism Clinics of North America” Polycystic Ovary Syndrome is linked to higher risk of hypertension and heart disease.
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January 1989 in “Toxicologic Pathology” Using minoxidil on dogs can cause serious cardiovascular damage, including arterial injury and hemorrhagic lesions.
56 citations,
April 2015 in “American journal of medical genetics. Part A” Patients with Bohring-Opitz syndrome and ASXL1 mutations need regular kidney ultrasounds to check for tumors.
49 citations,
May 2020 in “Frontiers in Public Health” Insulin resistance linked to obesity may increase COVID-19 severity.
43 citations,
August 2010 in “Expert Opinion on Investigational Drugs” Inhibitors of 11β-HSD1 show potential for treating type 2 diabetes but require more testing for safety and effectiveness.
42 citations,
March 2018 in “PLOS Biology” Autophagy is important for human hair growth and health.
41 citations,
September 2014 in “Journal of Pharmacy and Pharmacology” Melatonin may help treat PCOS symptoms in rats.
40 citations,
April 2008 in “European journal of endocrinology” Metformin and rosiglitazone both improved insulin use and hormonal symptoms in women with PCOS.
32 citations,
January 2007 in “KARGER eBooks” Severe insulin resistance can be managed with medication, lifestyle changes, and treatment for related conditions.
27 citations,
January 2020 in “Experimental Dermatology” Immune cells affect hair growth and could lead to new hair loss treatments.
26 citations,
October 2007 in “Experimental Dermatology” L-Carnitine-L-tartrate may help hair grow and prevent hair loss.
21 citations,
November 2014 in “Journal of Endocrinological Investigation” Cross-sex hormone therapy is important for managing gender dysphoria and requires careful monitoring and healthcare provider education.
16 citations,
October 2020 in “Lipids in Health and Disease” Leptin affects skin and hair health and may worsen some skin conditions, but more research is needed to understand its full impact.
15 citations,
June 2018 in “Life Sciences” Diabetex improves diabetic wound healing better than metformin.
13 citations,
October 2011 in “Clinical Obstetrics and Gynecology” Women with PCOS-related infertility can often conceive with treatments like clomiphene and metformin, but managing pregnancy complications is important.
11 citations,
April 2018 in “Nutrition Research” Chromium supplements don't help with weight loss or improve hormone and metabolism issues in people with polycystic ovary syndrome.
10 citations,
January 2018 in “Elsevier eBooks” Burn scars heal abnormally and more research is needed to find better treatments.
9 citations,
July 2020 in “Biomedicine & Pharmacotherapy” Mitochondrial therapy and platelet-rich plasma therapy both stimulated hair regrowth in aging mice, with mitochondrial therapy showing similar effectiveness to plasma therapy.
9 citations,
August 1952 in “The Journal of Clinical Endocrinology & Metabolism” A 17-year-old female with adrenogenital syndrome produces very high levels of androgens, which prevent complete feminization despite high estrogen doses.
9 citations,
March 2019 in “Science” Blocking cell death in certain stem cells can improve wound healing and tissue regeneration.
8 citations,
April 2019 in “Journal of the Endocrine Society” Postmenopausal women with hyperandrogenism didn't have better metabolic health even after their testosterone levels became normal.
5 citations,
May 2011 in “European Journal of Medical Genetics” A genetic duplication on chromosome 5 was linked to a woman's unique combination of medical conditions.
3 citations,
February 2018 in “Journal of evolution of medical and dental sciences” Some ovarian tumors can cause masculinization, and it's important to check for various causes when this symptom is present.