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Acne is a chronic disease linked to various systemic conditions and has significant psychological and social effects.

5-alpha reductase inhibitors can cause sexual side effects like erectile dysfunction and reduced sexual desire, sometimes lasting after stopping the drug.

Janus kinase inhibitors are promising drugs for treating autoimmune and inflammatory diseases.

Electrospun nanofibers show promise for enhancing blood vessel growth in tissue engineering but need further research to improve their effectiveness.

Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.

Lifestyle changes improve metabolism and fertility in overweight PCOS patients; anti-obesity drugs show potential but need more research.

Blocking a specific enzyme might help treat obesity and diabetes, but more research is needed to ensure it's safe.

Androgens slow hair growth by altering Wnt signaling in balding cells.

People with diabetes or obesity should manage their conditions carefully as they have a higher risk of severe COVID-19.

Cancer can hijack the body's cell repair system to promote tumor growth, and targeting this process may improve cancer treatments.

Prostaglandin D2 blocks new hair growth after skin injury through the Gpr44 receptor.

Abnormal Hedgehog signaling in blood cancers may help tumors grow and resist chemotherapy, suggesting potential for targeted treatments.

Shrinking skin cancer increases the chance of cancer in nearby lymph nodes.

Nonionic liposomes are the best for delivering genes to skin cells.

Estrogens and SERMs can help with skin aging, but their safety and effectiveness need more research.

Androgens cause skin issues like acne and hair growth in women, often due to PCOS, and can be treated with medication and lifestyle changes.

European guidelines recommend regular eye and ear exams, skin care, vitamin D supplements, and cautious use of medications for managing congenital ichthyoses.

The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.

The conclusion is that the best initial treatment for hirsutism is usually oral contraceptives, with the addition of antiandrogens or insulin sensitizers if needed, and topical eflornithine or laser treatments as supplementary options.

Androgens can both promote and prevent hair growth due to differences in gene expression in hair follicles.

Skin fat has important roles in hair growth, skin repair, immune defense, and aging, and could be targeted for skin and hair treatments.

Most low-level light therapy studies did not accurately report how light was measured, affecting treatment reliability.

Kennedy's disease leads to muscle weakness and sensory issues, has no cure but manageable symptoms, and future treatments look promising.

Noggin overexpression delays eyelid opening by affecting cell death and skin cell development.

The p53 protein has complex, sometimes contradictory functions, including tumor suppression and promoting cell survival.

The transscrotal testosterone patch normalizes hormone levels in men with AIDS and weight loss but does not improve weight, body mass, or quality of life.

People with alopecia areata often have lower levels of vitamin D, zinc, and folate, but more research is needed to understand if supplements can help treat it.

Improving insulin sensitivity and weight loss can help manage polycystic ovary syndrome (PCOS).

Low iron and vitamin D levels are linked to hair loss in women.

Genetic screening is crucial for accurately diagnosing APS-1 due to its varied symptoms.