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The structure of SRD5A reveals how it reduces steroids, aiding drug design for related health conditions.

Sex hormones affect reproduction, sexual development, and oral health, and it's important for dental practitioners to understand their effects and interactions.

Looking older on the outside might be linked to aging faster on the inside and can be affected by lifestyle choices and health risks.

Hormones affect skin aging, and treatments targeting hormonal balance may improve skin health.

Diabetes can cause a variety of skin disorders, some of which may signal more serious health issues.

The document concludes that PCOS is a complex disorder caused by both genetic and environmental factors, affecting women's health in various ways, and requires personalized treatment.

Vitiligo is a skin condition causing white spots, more common in women, often starts before age 20, and can affect mental health.

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

Obesity worsens PCOS symptoms, and PCOS may lead to more weight gain; managing both requires a holistic approach that includes mental health.

Testosterone therapy is generally safe for transmen, improves sexual function, and has manageable health risks with proper monitoring.

Gonadal dysgenesis, like Turner's and Klinefelter's syndromes, negatively affects bone health, but hormone treatments can help.

Lifestyle changes are the main treatment for PCOS, which is a complex condition requiring early management to reduce its health impacts.

The ITGB6 gene is important for tissue repair and hair growth, and mutations can lead to enamel defects and other health issues.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Testosterone therapy can help women with androgen deficiency by improving energy, sex drive, and bone health with few side effects.

Androgen therapy can help with symptoms like low libido in women, but more research is needed to understand its long-term safety and effects on health.

Hutchinson-Gilford Progeria Syndrome is a rare genetic disorder caused by a specific gene mutation, characterized by aging symptoms and managed by monitoring heart health and using low-dose aspirin.

The conference presented findings on how vitamin D levels, genetic factors, and lifestyle choices like smoking and yoga affect various health conditions and diseases.

The conclusion is that the nuclear lamina and LINC complex in skin cells respond to mechanical signals, affecting gene expression and cell differentiation, which is important for skin health and can impact skin diseases.

Early signs of PCOS in girls, like irregular periods and polycystic ovaries, suggest a need for early diagnosis and intervention to prevent further health issues.

Women with polycystic ovary syndrome have a higher risk of certain fractures.

Removing myelin protein zero-like 3 in mice leads to better metabolism and resistance to obesity.

Astaxanthin may improve health by reducing inflammation, stress, and cholesterol, and by enhancing skin health and sports performance.

Eating cream can increase ovarian androgen production in women with Polycystic Ovary Syndrome, which is not related to obesity.

High levels of fatty acids are linked to increased androgen production and inflammation in women with PCOS, which may affect IVF outcomes.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

Hormone therapy is essential for transgender individuals but requires careful management due to possible metabolic effects.

Testosterone supplements can increase muscle mass and strength in older men with low levels, but long-term effects and risks need more research.

DGAT1 enzyme is crucial for healthy skin and hair by regulating retinoid levels.

Vitamin D and its receptor are essential for hair growth, cell regulation, immune function, and heart health.