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Amenorrhea, or the absence of periods, should be evaluated by age 15 or within five years of early breast development, and is most commonly caused by conditions like polycystic ovary syndrome and hypothalamic amenorrhea.

Early treatment of acne is crucial to prevent scarring and psychological effects.

The letter suggests that psychiatric issues, not a sleep disorder, were likely the cause of a patient's self-inflicted leg ulcers.

Raising awareness about PCOS can improve women's quality of life.

Different medications can cause serious side effects in some people.

Acne vulgaris is a common skin condition that can cause low self-esteem and depression, and early treatment is important to prevent scarring.

Genetic mutations can affect female sexual development, requiring personalized medical care.

The document reviews key historical figures and discoveries in dermatology.

Swiss experts recommend specific guidelines for diagnosing and treating hidradenitis suppurativa to improve patient care.

High Nesfatin-1 and low Vitamin D may increase blood pressure and heart rate in women with PCOS.

The document concludes that inflammation markers can be used in diabetes, vitamin D3 affects immune pathways, hyperthyroidism changes hormone levels, androgen levels help diagnose Adrenocortical Carcinoma, erectile dysfunction is linked to diabetes, hypogonadism is common in HIV-infected males, and hormones can be biomarkers for various conditions.

Some lesser-known causes of PCOS include autoimmune issues, genetic mutations, and changes in the body's microbiome.

Acetylcholine receptors might be involved in the development of acne inversa and smoking could worsen the condition.

A 2-year-old boy had no hair and unusual organ placement, and it's unclear if it's genetic or coincidental.

Skin's uneven surface and hair follicles affect its stress and strain but don't change its overall strength, and help prevent the skin from peeling apart.

Certain mice without specific receptors or mast cells don't lose hair from stress.

Genetic testing is crucial for diagnosing congenital atrichia, a rare condition causing irreversible hair loss.

A gene mutation in mice causes permanent hair loss and skin issues.

A rare ear-area hair cyst was successfully removed from a 10-year-old boy.

Telomere damage affects skin and hair follicle stem cells by messing up important growth signals.

The document concludes that non-scarring alopecias can be reversed, but scarring alopecias cause permanent hair loss.

Nellore cattle have genetic variations linked to their adaptation to tropical environments.

Western diet may cause male pattern baldness; low glycemic diet with magnesium could help.

Fish oil improves skin health in people with diabetes and high cholesterol.

The document reports the 19th global case of a rare skin condition in a patient from Colombia.

Testosterone is important for male sexual traits, reproduction, muscle and bone health, blood production, and metabolism, and works both directly and after being changed into other hormones.

Cirsium japonicum flower extract increases melanin production and could help treat depigmentation conditions.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

Regulatory T cells help heal skin and grow hair, and their absence can lead to healing issues and hair loss.

Injectable platelet-rich fibrin has improved healing and regeneration in various medical fields and can be more effective than previous treatments.