November 2025 in “International Journal of Molecular Sciences” This review covers the diverse clinical applications of platelet-rich plasma in regenerative medicine but provides no new clinical results.
2 citations
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April 2022 in “Der Hautarzt” This review discusses the current literature on platelet rich plasma injections for androgenetic alopecia, noting that while some studies report positive outcomes, they often suffer from methodological weaknesses and inconsistent results.
This study found that local heterologous leukocyte-rich platelet-rich plasma improved distal skin flap viability in rats by reducing necrosis compared to the control group.
December 2021 in “Journal of clinical images and medical case reports” This review compares mesotherapy and PRP for hair loss but reports no new clinical results; the authors highlight the need to understand their differences for optimal treatment choices.
21 citations
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February 2023 in “Bioengineering” This review outlines current European legislation and manufacturing standards for platelet-rich plasma (PRP) products and provides guidance for clinicians implementing autologous PRP treatments, without reporting new clinical results.
2 citations
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June 2021 in “Bezmialem Science” This study found that using a centrifugation speed of 1800 rpm for 10 minutes is optimal for preparing platelet-rich plasma with PRPBAG®, yielding an eightfold increase in platelet concentration.
May 2015 in “Hair transplant forum international” This article contains no research findings; it reports on an online discussion about platelet-rich plasma (PRP) and opinions shared during a conference.
November 2025 in “Journal of Clinical Medicine” This study found that platelet-rich plasma may improve patient-reported outcomes for scar symptoms like pain and itching at six months, although no significant changes in scar appearance were observed at three months.
71 citations
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December 2018 in “Journal of Pain Research” This study suggests that controlling variables during platelet-rich plasma preparation and application may improve its reliability and effectiveness in providing long-term relief from chronic pain.
6 citations
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May 2021 in “Aesthetic Surgery Journal” This study found that intradermal injections of platelet-rich plasma were equally safe and effective for treating androgenetic alopecia, with higher platelet numbers possibly enhancing hair density and follicle diameter.
1 citations
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August 2023 in “Bioengineering” This review explores the potential benefits of platelet-rich plasma for anti-aging and tissue regeneration, especially in orthopedic applications like osteoarthritis, but it reports no new clinical results.
1 citations
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December 2022 in “Archives of Dermatological Research” This study compared fluid PRF and PRP for treating atrophic acne scars and found PRF to be more effective, particularly when combined with needling. Both treatments improved scars, but PRF showed higher therapeutic response, suggesting it as a superior alternative for acne scar treatment.
March 2026 in “Journal of Cosmetic Dermatology” This review discusses platelet-rich plasma therapy for androgenic alopecia and reports no clinical results; the authors emphasize the need for standardized protocols and large-scale studies to confirm its long-term efficacy.
March 2026 in “Journal of Ovarian Research” This review explores the potential of platelet-rich plasma therapy for early ovarian reserve decline and premature ovarian insufficiency, indicating some ovarian function improvements in initial studies but highlighting the need for further research.
April 2018 in “Selçuk Üniversitesi Tıp Fakültesi dergisi” This study found that repeated PRP injections in patients with androgenetic alopecia may lead to hyperalgesia, where pain is felt with less stimulus after each treatment.
April 2017 in “Al-Azhar Medical Journal” In this study conducted at Al-Azhar University Hospital, 60% of patients with localized alopecia areata responded to treatment with autologous platelet-rich plasma, with 89% of responders showing substantial improvement, suggesting PRP as an effective treatment option for this condition.
November 2022 in “Journal of Nanobiotechnology” In this study, researchers used a new method with platelet-rich plasma-loaded microcarriers to enhance dermal papilla cell activity and hair follicle regeneration, achieving significant hair and vessel growth in a mouse model compared to control groups.
August 2024 in “Journal of Cosmetic Dermatology” This study reported significant improvements in hair density and growth ratio in androgenetic alopecia patients receiving concentrated growth factor injections, with benefits sustained for 6 months.
19 citations
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January 2017 in “International Journal of Trichology” This study found that a standardized PRP application protocol was effective as a coadjuvant therapy in most patients with androgenetic alopecia who did not respond to minoxidil or finasteride, based on improvements in Ebling's scale.
December 2021 in “International Journal of Research in Dermatology” This review examines the use of platelet-rich plasma for treating alopecia and highlights current challenges in preparation standards and efficacy, without presenting new clinical findings.
39 citations
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January 2016 in “Journal of Cutaneous and Aesthetic Surgery” This study found that intra-operative platelet-rich plasma therapy may enhance hair regrowth, increase graft density, and activate dormant follicles more effectively than normal saline in follicular unit extraction hair transplant patients.
9 citations
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July 2019 in “Journal of cosmetic dermatology” This pilot study suggests that topical PRP may improve facial rejuvenation, with observed enhancements in collagen production and skin architecture over 8 weeks.
1 citations
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March 2023 in “International Journal of Trichology” This study found that Williams' Medium E and a 37°C storage temperature significantly enhanced hair growth in organ cultures compared to Ringer's lactate solution and 4°C, while PRP's impact on hair graft preservation was not significant.
3 citations
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November 2021 in “Clinical, Cosmetic and Investigational Dermatology” This review evaluated existing studies on platelet-rich plasma for facial rejuvenation and found limited clinical evidence supporting its effectiveness, suggesting that more research is needed to establish its utility.
February 2020 in “International Journal of Research in Dermatology” This study found that platelet-rich plasma therapy showed varying levels of improvement in patients with androgenetic alopecia, though it is not yet considered evidence-based for this condition.
26 citations
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January 2025 in “iScience” This article reviews the potential applications, benefits, and limitations of platelet-rich plasma in medical practice and reports no new clinical results, emphasizing the need for standardized preparation and treatment protocols.
September 2025 in “Journal of the Egyptian Womenʼs Dermatologic Society” This study found that using platelet-rich plasma as a storage solution in follicular unit extraction hair transplantation significantly improved hair regeneration, density, and graft quality compared to normal saline.
November 2024 in “Journal of Cutaneous and Aesthetic Surgery” This study reported two cases of severe multifocal alopecia areata successfully treated with a combination of topical minoxidil and intralesional platelet-rich plasma, resulting in significant hair regrowth, though further controlled trials are needed to confirm these findings.
18 citations
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March 2022 in “Drug design, development and therapy” This review examines the definition, classification, mechanism, clinical efficacy for hair regrowth, and potential adverse effects of platelet rich plasma, but does not present new experimental results.
2 citations
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June 2021 in “Cosmoderma” This article reviews the use of platelet-rich plasma (PRP) in various dermatological conditions and reports no new clinical results; the authors emphasize its efficacy and call for continued careful use.