Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This case report documents a female toddler with novel compound heterozygous mutations in the VDR gene causing hereditary 1,25-dihydroxyvitamin D-resistant rickets, expanding the known mutation spectrum for this disease.

This article describes the efficient synthesis of (S)-N-(2-bromo-6-methoxypyridin-4-yl)-2-hydroxy-2,4-dimethylpentanamide, a novel topical antiandrogen, with high purity and enantiomeric excess but reports no pharmacological results.

This study suggests melatonin may promote cashmere growth in Inner Mongolian cashmere goats through the nuclear receptor RORα, with a noted mRNA expression difference in December compared to other months.

This study found that a novel R343H mutation in the vitamin D receptor gene impairs its transcription activity, contributing to hereditary vitamin D-resistant rickets and alopecia in the affected family.

This study observed that expanding regulatory T cells in the skin of mice with alopecia areata did not reverse the condition, indicating that additional immunotherapy may be necessary.

This study suggests that analyzing hair samples with a liquid chromatography-mass spectrometric assay may offer a reliable method to measure average quarterly vitamin D levels, potentially complementing blood tests.

This chapter discusses the sources, classifications, and effects of hormones, their role in disease treatment and food security, and reports no new results.

This study suggests that using glycosidases to lyse the polysaccharides of Botryoccocus braunii may allow for the semi-continuous recovery of hydrocarbons while keeping the cells viable.

In this study, researchers found that the efflux of calcium in root hairs of Arabidopsis thaliana, particularly through the ER-localized ACA2 and ACA7, is crucial for modulating cytoplasmic calcium signals and enabling proper root hair growth, with disruptions leading to impaired elongation.

In this study, the researchers reported that a newly developed PYGL inhibitor, HTPI, enhanced hair growth in an ex-vivo culture by reducing oxidative damage in hDPCs and inhibiting glycogen degradation in hORSCs, showing potential as a treatment for hair loss comparable to minoxidil.

This study observed that exposure to different wavelengths of light affects opsin and clock gene responses in skin cells, suggesting potential therapeutic approaches using photobiomodulation for dermatological conditions like psoriasis and wound healing.

The document concludes that managing skin conditions during pregnancy is important and requires specialized care.

This review explores potential new roles for Merkel cells, including involvement in magnetoreception, fingerprint formation, and transmitting environmental information, but reports no experimental results.

This review discusses the applications of low level laser therapy (LLLT) in wound healing, pain reduction, and treating various conditions, but reports no new clinical results; the authors highlight the need for randomized controlled trials for serious diseases.

This article reviews the complex signaling pathways between epithelial and mesenchymal cells crucial for hair follicle morphogenesis, highlighting the Wnt pathway's role as a master regulator without reporting new experimental findings.

This review discusses the effects of visible light on human skin, highlighting its role in pigmentation, thermal damage, and the treatment of several skin conditions, while noting limited sunscreen protection against it; no new clinical results are reported.

This study found that hMSC secretomes from umbilical cord Wharton's jelly had the most potent angiogenic effects, whereas those from adipose tissue demonstrated the weakest angiogenic potential.

In this study, researchers used genetic data from over 52,000 men to identify over 250 genetic loci associated with severe hair loss and developed a predictive algorithm for determining hair loss risk.

This research found that liquid-state liposomes and niosomes may enhance finasteride delivery to pilosebaceous units in hamsters more effectively than gel-state vesicles or hydroalcoholic solution.

This review discusses the potential of ultraviolet (UV) radiation technologies in wound care, highlighting their antimicrobial properties and risks of DNA damage, but reports no new clinical findings.

This study reported that 4D-printed, aliphatic polycarbonate-based scaffolds supported adipose tissue engineering by allowing adipocyte infiltration and neovascularization in vivo, indicating potential for effective adipose tissue repair.

This study suggests that spironolactone-loaded nanostructured lipid carriers could enhance follicular delivery and offer a more localized treatment for androgenic alopecia, potentially reducing systemic side effects.

This review discusses different preparation and application methods of platelet-rich plasma in dental regenerative medicine and reports no new results, highlighting its potential and associated controversies.

This review highlights how advanced nanocarrier and microneedle-based transdermal drug delivery strategies can potentially improve the treatment of skin diseases by enhancing site-specific drug delivery, increasing skin penetration, and reducing systemic toxicity compared to conventional methods.

This review discusses the various skin manifestations associated with end-stage renal disease and their potential causes but reports no new clinical findings; the authors emphasize pruritus as a significant condition.

This review discusses the causes, clinical presentation, and management of anagen effluvium, emphasizing its psychological impact and the need for empathy and practical support, but reports no new results.

This study found that cyclosporin A treatment enhances hair growth in mice by inhibiting calcineurin-NFAT1 activity, which alters keratinocyte differentiation and apoptosis-related gene expression in hair follicles.

This study found that a novel skin patch combining extracellular matrix and ciprofloxacin promotes advanced wound healing and skin regeneration in mouse models of infected wounds.

In this study, mice exposed to prolonged space conditions demonstrated skin atrophy, altered hair follicle cycles, and significant changes in the gene expression associated with skin muscle health.

This review explores how sex differences influence the pathophysiology, incidence, and treatment outcomes of ischaemic heart disease, and emphasizes the need for more sex-specific research.