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Stem cells help remove dead cells to keep tissues healthy by balancing cell replacement and clearance.

Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.

Runx1 controls fat-related genes important for normal and cancer cell growth, affecting skin and hair cell behavior.

Too much β-catenin activity can mess up the development of mammary glands and make them more like hair follicles.

Aging causes skin stem cells to work less effectively.

Macrophages help regrow hair by activating stem cells using AKT/β-catenin and TNF.

Hydrogel microcapsules help create cells that boost hair growth.

Keratins help protect cells, aid in cancer diagnosis, and influence cancer behavior and treatment.

Special fiber materials boost the healing properties of certain stem cells.

Human hair follicle stem cells can turn into multiple cell types but lose some of this ability after being grown in the lab for a long time.

The review found that different stem cell types in the skin are crucial for repair and could help treat skin diseases and cancer.

The conclusion is that certain cell interactions and signals are crucial for hair growth and regeneration.

Stem cell self-renewal is complex and needs more research for full understanding.

Calcium is important for stem cell function and maintenance, especially in blood and skin cells.

Estrogen is important for keeping adult mouse nipple skin healthy by controlling certain cell signals.

Tiny pollution particles called PM2.5 can harm skin cells by causing stress, damage to cell parts, and cell death.

Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.

The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

Sebaceous glands can heal and regenerate after injury using their own stem cells and help from hair follicle cells.

The mesenchyme can start hair growth, but the exact signal that causes this is still unknown.

Skin and hair renewal is maintained by both fast and slow cycling stem cells, with hair regrowth primarily driven by specific stem cells in the hair follicle bulge. These cells can also help heal wounds and potentially treat hair loss.

The document concludes that while significant progress has been made in understanding skin biology and stem cells, more research is needed to fully understand their interactions with their environment.

MicroRNA-214 is important for skin and hair growth because it affects the Wnt pathway.

Most hair follicle stem cells do not protect their DNA by dividing it unevenly.

Hair follicles are valuable for regenerative medicine and wound healing.

New treatments targeting immune pathways show promise for severe hair loss but need more research for safety and effectiveness.

Cholesterol balance is important for hair health, and problems with it can lead to hair loss conditions.

Hair growth environment recreated with challenges; stem cells make successful skin organoids.

The hair treatment made hair grow faster and thicker and strengthened the hair roots.

The document concluded that stem cells are crucial for skin repair, regeneration, and may help in developing advanced skin substitutes.