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This review discusses how recent studies use models and experiments to understand immune system signaling, but it reports no new clinical findings; the authors suggest strategies for improving these models.

This study demonstrates that keratinocyte cell lines derived from cultured hair follicles can fully differentiate in organotypic skin models, offering a minimally invasive alternative to obtaining keratinocytes for research.

This review discusses targeting host cell proteases as a novel approach to inhibit SARS-CoV-2 infection, highlighting transcriptional modulation and enzymatic inhibition as promising therapeutic strategies, but it reports no new clinical findings.

This article discusses the cell therapy potential of follicular cell implantation for hair regeneration and reports no new clinical results, emphasizing the role of dermal papilla cells in forming new follicles.

This review discusses the role of collagen XVII in maintaining stem cell niches and its impact on skin aging and wound repair, without reporting new clinical results.

This chapter discusses the skin stem cell niche as a complex ecosystem and highlights the diverse components and interactions that influence stem cell function, but it reports no new experimental results.

This study found that thymus transplantation in athymic mice resulted in T-cell-driven hair follicle depigmentation and loss, without multiorgan autoimmune disease, highlighting mechanisms of tissue-specific tolerance.

This study introduced a simple and reliable in vitro assay capable of large-scale simultaneous screening of hair growth-promoting compounds using a 3D co-culture system of human dermal papilla and outer root sheath cells.

This study found that epidermal stem cells in nonglabrous skin are connected to the distal end of the arrector pili muscle, which may play a role in epidermal renewal and wound healing.

In this narrative review, researchers outlined the role of T cells in the autoimmune pathogenesis of alopecia areata and highlighted ongoing research into therapeutic pathways, beyond current JAK inhibitors, aimed at developing new treatments for the disease.

This review discusses the impact of calorie restriction on enhancing stem cell potency and regenerative abilities in mammalian tissues and reports no new experimental results.

This study found that basal cell carcinoma cells differentiate along hair follicle lineages and may be influenced by hair follicle cycle modulators for potential therapeutic targeting.

This review discusses the impaired functionality of regulatory T cells in the pancreas during the development of Type 1 diabetes, highlighting their role in disease pathogenesis, potential of Treg-based therapies, and challenges in clinical applications.

This study found that in a mouse model of PCOS, high androgen levels caused pyroptosis in ovarian granulosa cells and increased ER stress in oocytes, reducing oocyte maturation rates, while treatment with CPA and DMF improved these rates.

This review highlights the promising role of stem cell therapy in treating resistant diseases, while also addressing the challenges in production and clinical application, emphasizing the need for standardized manufacturing and quality assurance to enhance efficacy and safety in clinical translational research.

In this study, researchers using a Treg-specific HuR-deficient mouse model found that the RNA-binding protein HuR is crucial for stabilizing Foxp3 mRNA, affecting Treg function and immune regulation, with HuR disruption leading to impaired Foxp3 expression and potential autoimmune dysfunction.

This study found that Polycomb repressive complex 1 is crucial for skin development and stem cell specification, influencing gene activity beyond its known repressor functions.

This review summarizes discussions from a 2010 stem cell biology meeting, covering the origin, behavior, and therapeutic potential of pluripotent and multipotent stem cells, without reporting new experimental findings.

At the 21st Royan International Stem Cell Congress, researchers highlighted the growing integration in regenerative medicine, emphasizing advances in pluripotency, AI applications, and bioengineering for the development of accessible stem cell therapies.

This meta-analysis found that autologous cell-based therapies, especially stromal vascular fraction, significantly improved atrophic acne scars over control treatments, enhancing both clinical and patient-reported outcomes.

This study suggests that using cell-free dexamethasone-primed stem cell media may offer a promising alternative treatment for systemic lupus erythematosus, showing immunomodulatory benefits and therapeutic efficacy in reducing various complications.

In this study, the researchers found that deleting ceramide synthase 4 in the skin's epidermis alters stem cell differentiation, disrupting hair follicle structure and barrier function, potentially leading to immune responses similar to atopic dermatitis.

This study found that overexpressing Rps14 in supporting cells promoted hair cell regeneration in the organ of Corti by facilitating cell proliferation and differentiation.

This study established the R-7 dermal papilla cell line, which retained essential characteristics of primary cells without undergoing malignant transformation, suggesting its potential for future hair research.

Hair can regrow after certain stem cells are lost because other stem cells can take over their role.

This research discusses a novel imaging approach in live mice to study stem cell and niche interactions in tissue homeostasis and reports no new results.

This study found that stem cells derived from spinal and bulbar muscular atrophy patients exhibited reduced androgen receptor levels and HDAC6, providing potential insights into the disease mechanism for future therapies.

Basal cell carcinoma mostly starts from cells in the upper skin layers, not hair follicle stem cells.

This study found that the circadian clock regulates the activation state of murine epidermal stem cells, affecting tissue homeostasis and susceptibility to tumorigenesis when disrupted.

This review discusses the role of stem cell progeny as integral components of stem cell niches, offering feedback that may influence different stem cell systems' microenvironments, but it presents no new research findings.