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Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

AIRE-deficient rats developed severe autoimmune disease similar to APECED, useful for testing treatments.

The document concludes that diagnosing PCOS in teenagers is difficult and should focus on specific hormone levels and menstrual irregularities, while also considering treatment for symptoms and related health issues.

Testosterone therapy can modestly improve sexual function in menopausal women but should be used cautiously and is not recommended for routine measurement in sexual dysfunction or hirsutism.

Adult stem cells with Tp63 can form hair and skin cells when placed in new skin, showing they have hidden abilities for skin repair.

Antihelminthic drugs treat worm infections but face challenges like low treatment coverage and potential drug resistance, with various side effects reported for different drugs.

The Middle East and Africa need better data, treatment consensus, and support for Alopecia Areata.

Skin organoids from stem cells could better mimic real skin but face challenges.

SHISA6 helps maintain certain stem cells in mouse testes by blocking signals that would otherwise cause them to differentiate.

The circadian clock influences the behavior and regeneration of stem cells in the body.

Recent genetic insights show that low-renin hypertension includes a range from essential hypertension to secondary or familial forms, affecting diagnosis and treatment.

Testosterone significantly affects urination differences between male and female mice.

Green tea component EGCG could potentially promote human hair growth.

Olive oil compounds may help prevent cancer in animals, but human results are mixed.

Wnt10b helps blood stem cells grow after injury.

Researchers developed a 3D model of human hair follicle cells that can help understand hair growth and test new hair loss treatments.

Removing integrin α3β1 from hair stem cells lowers skin tumor growth by affecting CCN2 protein levels.

Metformin helps improve skin regeneration by increasing the growth of skin stem cells.

Blocking the Mitochondrial Pyruvate Carrier causes stress in hair follicles, which can be reduced by an ISR inhibitor.

Melatonin helps hair grow by activating a specific signaling pathway.

A special gene region controls the re-emergence of a primitive wool type in Merino sheep, improving their wool yield and adaptability.

Damaging mitochondrial DNA in mice speeds up aging due to increased reactive oxygen species, not through the p53/p21 pathway.

Mobile phone radiation may cause DNA damage in human ear hair follicle cells.

The document says that hookworms are treated with mebendazole and stress-related hair loss usually gets better in 6 months, while other hair loss types have specific treatments.

Short-chain fatty acids from *Cutibacterium acnes* cause skin inflammation, contributing to acne.

DNA variants can predict male pattern baldness, with higher risk scores increasing baldness likelihood.

Human liver cells stick to hair protein materials mainly through the liver's asialoglycoprotein receptor.

Quick, selective detection of tadalafil and finasteride in human plasma developed.

Oxidative stress may contribute to hair loss in alopecia areata and antioxidants could potentially help as a treatment.

New method measures finasteride in plasma, finds two formulations bioequivalent.