Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study found that basal cell carcinomas show strong expression of vitamin D receptors at both mRNA and protein levels, suggesting a potential role in tumor growth regulation.

This study found that stem cell therapy significantly improved burn healing rates in animal models, with hair follicle stem cells showing particularly strong effects.

Researchers developed a new way to measure gene activity in single hair follicles and found that a specific gene's activity changes with different amounts and times of treatment.

This study found that single high-dose irradiation in mice induced more severe acute skin injury and hair depigmentation, while fractional doses led to longer-term damage in the dermis and subcutis.

This study found that among female patients with acute telogen effluvium, 83.7% reported either partial or complete resolution of hair shedding after three months of treatment including vitamin E and zinc supplements.

This study found that hMSC secretomes from umbilical cord Wharton's jelly had the most potent angiogenic effects, whereas those from adipose tissue demonstrated the weakest angiogenic potential.

In this study, only a subset of proposed biomarkers universally responded to priming in mesenchymal stromal cells, suggesting limited utility for standardized potency assays across different MSC types and conditions.

This study retrospectively analyzed 945 patients with head and neck cSCC to identify risk factors for recurrences, reporting treatment modality, tumor characteristics, and patient factors such as immunosuppression as strong predictors for loco-regional recurrences.

This review discusses the advancements in intraoperative stem cell therapies and highlights their potential to improve hair regrowth, but it reports no new clinical results.

In this study, researchers found that ligand homodimerization controls the receptor binding specificity of the FGF9 subfamily, preventing off-target activation of FGFR "b" isoforms.

This study reported that Sintilimab combined with chemotherapy may improve outcomes in advanced NSCLC patients but carries a higher risk of certain side effects, including hypothyroidism.

This study found that androgenic alopecia was associated with a decreased risk of testicular germ cell tumors but a potential increased risk of high-grade prostate cancer.

In this study, the researchers developed and optimized a curcumin nanocrystal gel to enhance skin permeability, reporting improved dissolution properties and antiproliferative effects on cell lines, suggesting it as a promising topical delivery system.

In this study, researchers observed that a significant number of women in Eket, Nigeria, have low testosterone levels, while a subset with high free testosterone may have polycystic ovary syndrome.

Haplogroup X found in Altaian population supports Amerindian origin.

This study suggests that potent topical corticosteroid occlusion may be a safe and effective treatment option for pediatric patients with severe alopecia areata, although further research is needed on its long-term safety and recurrence.

This study found that monocytes/macrophages with a pro-inflammatory M1-like phenotype may play a crucial role in the pathogenesis of hidradenitis suppurativa, suggesting potential therapeutic targets.

This study found that targeting IL-6, IL-1, and CCR6 signaling pathways may effectively reduce irradiation-induced alopecia and dermatitis in radiotherapy patients.

This study suggests that the CXCL8 gene may regulate cashmere fineness in Liaoning cashmere goats, providing new insights into the cellular mechanisms of cashmere growth and quality.

This study used single-cell RNA sequencing to characterize 19 distinct cell populations in sheep hair follicles, uncovering differentiation signatures and intercellular communication that may influence wool curvature and sheep breeding.

This study identified highly variable genes in mesenchymal stem/stromal cells that are linked to classic functions like development and inflammation response, suggesting their potential as markers for further potency studies.

This study identified dual epithelial and mesenchymal traits in dermal sheath cells during wound repair, suggesting they could be targeted to enhance healing.

This study introduces scINSIGHT, a method to analyze single-cell RNA sequencing data that outperforms existing techniques in identifying gene expression patterns across different biological conditions.

This study identified genes that may regulate cashmere fineness in Liaoning Cashmere Goats by analyzing skin cell types and exploring gene expression in secondary hair follicle dermal papilla cells.

This research by Yuan et al. focused on developing a comprehensive human skin cell atlas, analyzing various cell types and diseases, and introduced a deep learning method, scSEA, for unbiased reference mapping, potentially discovering new cell types.

The researchers developed a comprehensive human skin cell atlas using data from various studies and established a consensus nomenclature for normal human skin in this project, which also includes a deep learning-based method for more effective reference mapping of new cells.

Mechanical tension worsens keloid scars by activating inflammation and fibrosis pathways.

This study identified distinct and diverse fibroblast populations in female scalp cells that lose their signature and identity with age, highlighting significant age-related changes, such as increased fibrosis, DNA damage, and senescence, which may affect scalp dermal support for healthy hair follicles.

This study used single-cell and spatial transcriptomic profiling to identify specific molecular markers in human follicular dermal papilla cells, enhancing understanding of their role in hair follicle development.

This study used advanced single-cell RNA and chromatin sequencing to investigate differences in peripheral blood cells between mild and severe alopecia areata patients, uncovering shared transcription factor motifs that may explain disease severity and open avenues for future research on therapeutic targets.