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The niche environment controls stem cell behavior and plasticity, which is important for tissue health and repair.

The conclusion is that grasping how cells determine their roles through evolution is key, with expected progress from new research models and genome editing.

Hydrogel microcapsules help create cells that boost hair growth.

A protein called EGFR protects hair follicle stem cells, and when it's disrupted, hair follicles can be damaged, but blocking certain pathways can restore hair growth.

Inflammation plays a key role in activating skin stem cells for hair growth and wound healing, but more research is needed to understand how it directs cell behavior.

Removing centrosomes from skin cells leads to thinner skin and stops hair growth, but does not greatly affect skin cell differentiation.

Dermal EZH2 controls skin cell development and hair growth in mice.

Dermal EZH2 controls skin cell growth and differentiation in mice.

The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

Certain immune cells in the skin release a protein that stops hair growth by keeping hair stem cells inactive.

Diabetes causes lasting cell dysfunctions, leading to serious complications even after blood sugar is controlled.

Mathematical modeling can improve regenerative medicine by predicting biological processes and optimizing therapy development.

Innovative methods are reducing animal testing and improving biomedical research.

Non-immune dermal cells dominate, epidermal cells increase after day 9, and certain immune cells persist beyond inflammation in wound-induced hair follicle regeneration.

CD34+ and CD34- melanocyte stem cells have different regenerative abilities.

Fibroblasts, cells usually linked to tissue repair, also help regenerate various organs and their ability decreases with age. Turning adult fibroblasts back to a younger state could be a new treatment approach.

A special environment is needed to fully activate sleeping stem cells.

Ifidancitinib, a JAK inhibitor, effectively regrows hair in mice with alopecia by tiring out harmful T cells.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

Different types of cell death affect skin health and inflammation, and understanding them could improve treatments for skin diseases.

A specific group of skin stem cells was found to help maintain hair follicle cells.

Mast cells and CD8 T cells interact closely in skin diseases, affecting each other's behavior and contributing to conditions like psoriasis and eczema.

Cells lacking the Bax protein can outcompete others, leading to better tissue repair and hair growth.

Newly born mesenchymal cells quickly spread out in response to tissue tension during early development.

Minoxidil may help reduce aging effects in brain cells.

Special immune cells called Regulatory T cells help control skin inflammation and repair in various skin diseases.

Removing REDD1 in mice increases skin fat by making fat cells larger and more numerous.

Newly divided skin cells quickly move to join skin structures due to tissue tension and specific signals.

The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.

Transit-amplifying cells are crucial for tissue repair and can contribute to cancer when they malfunction.