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Male and female skin differ in many ways, which could lead to gender-specific skin treatments.

Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

Overexpression of activin A in mice skin causes skin thickening, fibrosis, and improved wound healing.

Use minoxidil for hair loss; finasteride and dutasteride for men, dutasteride for women.

Male and female bodies respond differently to stress, influenced by hormones and development stages, with implications for stress-related diseases.

WNT10A mutations often cause ectodermal dysplasias, with males showing more tooth issues than females.

Sebocytes play a key role in controlling androgen levels in human skin.

High levels of male hormones, insulin resistance, and obesity are closely linked and worsen polycystic ovary syndrome, but more research is needed to improve treatments.

Dutasteride and finasteride may reduce sperm count and volume but don't affect movement or shape; effects are reversible after stopping.

A new microneedle patch made from hair proteins helps regrow hair faster and better than current treatments.

Targeted cancer therapies often cause serious skin problems that need careful management.

Metformin is effective for treating excessive hair growth in women with PCOS and may work better than the standard treatment in some ways.

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.

Hair follicle stem cells use specific chromatin changes to control their growth and differentiation.

Women with PCOS are more likely to have impaired glucose tolerance and type 2 diabetes, especially if they are Asian or obese.

Regulatory T-cells are important for healing and regenerating tissues in various organs by controlling immune responses and aiding stem cells.

The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.

Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.

Essential oils in cosmetics can offer benefits but may cause allergies and should be used carefully.

AA-PRP injections effectively increase hair count and thickness for male pattern hair loss.

Opioid painkillers can cause many side effects, including breathing problems and addiction, but are generally considered safe when used properly.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Cancer treatments targeting specific cells and the immune system can cause skin, mouth, hair, and nail problems, affecting patients' quality of life and treatment adherence.

Trichoscopy is a useful tool for diagnosing different hair and scalp diseases by their unique visual features.

COVID-19 can cause different skin symptoms that may help with early diagnosis and show how severe the disease is.

Alopecia areata involves immune activation in the scalp, suggesting treatments targeting TH1, TH2, and IL-23 pathways.

Hair stem cell regeneration is controlled by signals that can explain different hair growth patterns and baldness.

Different types of skin cells have unique genetic markers that affect how likely they are to spread cancer.

Capsaicin, found in chili peppers, can slow down hair growth by affecting skin cells and hair follicles.

Some medicinal plants can help heal wounds and may lead to new treatments.