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This review discusses recent advancements in hair follicle organoid technology for alopecia treatment but presents no new experimental results, emphasizing the potential for clinical applications and drug screening.

This review examines how biochemical and biophysical induction factors influence cell fate in tissue engineering and reports no new experimental results.

This paper reviews the benefits of using silk proteins as natural ingredients in cosmetics, highlighting their potential for improving skin and hair health due to properties like antimicrobial activity, UV resistance, and enhanced moisture absorption.

This study reports that Echinacea-loaded silk fibroin/chitosan dressings may effectively promote scarless skin regeneration and accelerate wound healing compared to conventional treatments.

In this study, shear-thinning silk nanofiber hydrogels were found to enhance retention of mesenchymal stem cells and accelerate wound healing in rat models.

This study investigated various proteins as eco-friendly hair perming agents for Asian hair and found that bovine serum albumin and keratin achieved perming results comparable to commercial products, while also increasing hair moisture, indicating a protective effect during heat styling.

This study reports that a heparin-based sericin hydrogel encapsulating basic fibroblast growth factor significantly accelerated wound healing in mice by enhancing vascularization, re-epithelialization, and collagen deposition.

This chapter discusses the composition, biocompatibility, and production methods of biomaterials like collagen, chitin, and silk for dermal substitutes, focusing on preclinical and clinical research, but reports no new clinical results.

In this study, small molecule-loaded silk fibroin nanofiber scaffolds with chitosan achieved sustained release of GSK-3 inhibitor SB216763, leading to enhanced wound healing and hair follicle neogenesis in skin regeneration efforts.

This review reports that sodium alginate-based hydrogels show promise in biomedical applications due to their biocompatibility and versatility, but challenges such as mechanical strength and stability remain, highlighting the need for continued research to facilitate their clinical transition.

This study found that using 3D dermal papilla spheroid models enhances extracellular matrix production and hair follicle marker expression, providing insights into hair follicle biology and potential for drug screening.

This review article discusses recent progress in chitosan-based hemostatic hydrogels, highlighting their unique properties, such as biocompatibility and enhanced hemostatic performance, compared to traditional materials. The authors summarize their hemostatic mechanisms and future potential in improving emergency bleeding control.

This study found that Forskolin-loaded carboxymethyl chitosan-silk nanofiber hydrogels promoted wound healing by accelerating wound closure, enhancing neovascularization, and supporting hair follicle regeneration, while also being non-toxic and encouraging the proliferation of certain cell types.

This study reported that newly developed RADA16-I peptide hybrids, with active motifs like GHK and KGHK, demonstrated improved wound healing in a mouse skin injury model without cytotoxicity, suggesting they might be effective scaffolds for tissue engineering and regeneration.

This review examines hydrogel microneedles for transdermal drug delivery, discussing their applications and challenges but reports no new clinical results.

This review discusses the potential of hydrogel-based interventions for radiation-induced skin injury, providing no new clinical results but highlighting their synergistic mechanisms and promise in improving treatment strategies.

This review outlines how combining biomembrane-based nanostructures and microstructures with hydrogels can enhance strategies for chronic wound healing, by utilizing the unique properties of both to address metabolic disturbances and severe symptoms in wound care.

This study reported that a newly developed hydrogel composed of recombinant type I collagen and chitosan, incorporating a metal–polyphenol structure, demonstrated strong mechanical and healing properties, effectively promoting wound healing in a full-thickness skin defect model.

This review discusses the biofunctionalization of hydrogel scaffolds for vascular tissue regeneration and reports promising results from in vivo studies, such as improved angiogenesis and healing in pressure ulcers when using specific peptides.

This review covers recent developments in materials for in vitro and in vivo stem cell manipulation, highlighting innovative substrate properties but does not report new experimental results.

This review reports that biopolymer-based hydrogels show promise as wound dressings due to their biocompatibility, moisture retention, and ability to mimic the extracellular matrix, though challenges in mass production, safety, and clinical validation remain.

This study found that a double-crosslinked hydrogel using GelMA and sulfhydrylated chitosan showed promising results in healing full-thickness skin wounds in rats by accelerating tissue repair and promoting collagen and blood vessel formation.

Animal experiments in this study demonstrated that a new sandwich-like fiber/sponge dressing design, which enhances wound healing through improved moisture management and faster exudate evaporation, resulted in more significant wound size reduction compared to commercial and control dressings.

New materials and methods could improve skin healing and reduce scarring.

This review discusses the growing importance of hydrogel scaffolds in skin wound healing, highlighting their unique properties and recent advancements in their use for treating difficult tissue damage, particularly within tissue engineering.

This study reported that a novel hydrogel wound dressing, created using a Brachybotrys paridiformis polysaccharide derivative and chitosan, significantly accelerated wound healing and tissue regeneration in vivo, showing nearly complete healing by day 15 compared to controls.

The hydrogel is safe, reduces oxidation, and helps heal wounds effectively.

In this study, researchers developed a new sodium alginate/chitosan/Zn2+ hydrogel that showed improved physical properties, antibacterial activity, and biocompatibility, and demonstrated enhanced wound healing and skin regeneration in an in vitro model.

This research found that keratin hydrogels derived from human hair may support cell viability and proliferation, indicating potential as 2D and 3D soft tissue culture scaffolds.

In this review, researchers reported that incorporating nanoparticles into natural-based biomaterials enhanced scaffolding properties, cellular interactions, and outcomes in wound healing, with promising implications for tissue engineering and regenerative medicine, although many signaling pathways involved are still not fully understood.