December 2025 in “Journal of Cell Communication and Signaling” This review discusses the role of vitamin D receptor signaling in hair follicle biology for alopecia treatment and underscores the need for continued research, without presenting new clinical results.
1 citations
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February 2025 in “South Asian Research Journal of Pharmaceutical Sciences” This study used in-silico molecular docking to evaluate the antidiabetic potential of Eclipta alba leaf flavonoids, finding that compounds like apigenin, syringic acid, and vanillic acid effectively bind to the target protein aldose reductase, suggesting a promising inhibitory action.
June 2022 in “Scientific Reports” This study found that prevelex coatings on microwell array devices enhanced the formation of uniform cell spheroids and enabled the development of hair follicles in tissue engineering applications.
November 2025 in “Quality in Sport” This review found that hydrolyzed collagen supplementation, particularly marine collagen, improves skin hydration, elasticity, and density while strengthening hair and nails, especially when paired with vitamin C and trace elements; however, more studies are necessary to evaluate long-term efficacy across different sources and demographics.
March 2025 in “Jurnal Farmamedika (Pharmamedica Journal)” In this study, Indonesian spices were screened in silico for their potential to inhibit MMP9 and TNFα, which are involved in chronic diabetic wounds, and procyanidin was identified as the most promising therapeutic candidate due to its low binding energy to both proteins.
2 citations
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December 2020 in “Phytomedicine plus” In this study, researchers found that taking Saw palmetto and Pygeum africana supplements for five days altered the urinary steroid profile in a way that may interfere with the steroidal module of the Athlete Biological Passport.
63 citations
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May 2017 in “American Journal of Clinical Dermatology” This review found that patients with alopecia areata may have lower levels of vitamin D, zinc, and folate, but conflicting evidence precludes definitive clinical recommendations for micronutrient supplementation.
45 citations
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March 2020 in “ACS Applied Materials & Interfaces” In this study, researchers created a novel fibrous membrane inspired by ancient Chinese medicine that effectively promotes hair follicle regeneration and wound healing in deep burn injuries by releasing quercetin, copper, and silicon ions.
October 2025 in “Scientific Reports” This study found that the extracts of Serenoa repens, when evaluated through chemical, biological, and in silico methods, demonstrated anti-inflammatory, pro-apoptotic, and anti-androgenic activities against prostate cancer cell lines, suggesting potential therapeutic benefits and directing future pharmaceutical development.
2 citations
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January 2019 in “Medizinische Genetik” Among families with pediatric brain disease, this study identified over 200 novel genetic causes, revealing potential treatment points using drug repurposing or nutritional supplementation.
October 2024 in “Open Repository of the University of Porto (University of Porto)” In this report, the author shares experiences from a six-month curricular internship, highlighting activities such as arterial pressure monitoring in a community pharmacy and addressing off-label rituximab use at a hospital, alongside discussions of hair loss treatments and nutritional supplementation for dysphagia in the elderly.
1 citations
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October 2022 in “Journal of food and nutrition research” This review investigates the potential benefits of cinnamon supplementation alongside lifestyle changes for managing obesity and polycystic ovary syndrome, but it reports no new clinical results.
February 2026 in “Toxicology Letters” This study used an in silico/in vitro approach to identify potential inhibitors of the enzyme SRD5A2, finding that the androgen receptor modulator MK-0773 is a moderate inhibitor, although it does not act as a covalent inhibitor like finasteride.
January 2024 in “Wiadomości Lekarskie” This study discusses the development of AI in dermatology and cosmetology, noting its use in skin cancer diagnosis and personalized cosmetics, while highlighting uncertainties about whether recent advancements represent significant medical progress or are influenced by marketing strategies.
December 2022 in “Journal of Education, Health and Sport” This review suggests that combining treatments such as oral supplements, topical minoxidil, and high-platelet plasma may be effective for addressing telogen effluvium after COVID-19 infection, which affects about 30% of patients.
In this clinical trial, the researchers observed that a biotin and silica supplement reduced hair fall, increased hair growth rate, and improved skin elasticity, hydration, and nail quality over 90 days without adverse effects.
12 citations
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July 2021 in “Scientific Reports” This study found that exogenous glutamic acid can promote hair growth and keratinocyte proliferation, suggesting a novel signalling pathway in the skin.
February 2026 in “Phycology” This review highlights the potential of microalgae as sustainable sources for nutraceuticals and cosmeceuticals, emphasizing their applications in functional foods, dietary supplements, and cosmetics for roles such as anti-aging and photoprotection in alignment with sustainability principles.
July 2025 in “Scientific Reports” This study reported that fermented grapeseed oil may enhance hair permeability and improve strength and color retention in chemically treated hair compared to regular grapeseed or silicone oils.
November 2024 in “VITEK Bidang Kedokteran Hewan” In this case study, treatment using ivermectin, antihistamines, topical antibiotics, and supplements resulted in clinical recovery from scabies-related symptoms in a domestic male cat, showing significant reduction in itching and skin lesions by the seventh day.
January 2024 in “Biotechnology advances” This review highlights the importance of selecting high-quality bioassays in discovering bioactive compounds from marine sources, emphasizing their role in evaluating safety and efficacy during pharmaceutical, food supplement, and cosmetic development.
November 2018 in “Annals of oncology” This study found that the computer-controlled RV-01 scalp cooling device helped prevent significant hair loss in metastatic breast cancer patients treated with eribulin, with none of the 16 patients requiring a wig and experiencing minimal discomfort.
188 citations
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May 2009 in “Plant physiology” This study identified 19 specific genes involved in root hair growth and morphogenesis in Arabidopsis, using a combination of computational and experimental methods.
4 citations
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July 2025 in “Molecular Diversity” This review outlines drug repurposing as an efficient, low-cost strategy to identify new uses for existing drugs, highlighting various computational and experimental approaches as well as publicly available databases to aid in personalized pharmacotherapy.
4 citations
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May 2017 in “Data in Brief” This study identified five potential molecular targets for future androgenetic alopecia therapy using genome-wide gene-expression investigations and bioinformatics analyses.
2 citations
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January 2025 in “Advances in Skin & Wound Care” This study from ISTAP emphasizes the importance of preventing skin tears, particularly in vulnerable populations like older adults and neonates, and recommends strategies such as using silicone-based adhesives, emollient therapy, and maintaining a safe environment to reduce the risk of these injuries.
March 2026 in “Jurnal Pharmascience” This study found that isorhamnetin, a compound from the Rampai plant, showed a lower affinity energy in molecular docking tests compared to Minoxidil, indicating potential as an androgen receptor antagonist for alopecia therapy in silico, with favorable pharmacokinetic characteristics in ADME-Tox predictions.
134 citations
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December 2018 in “Dermatology and Therapy” This review discusses the potential role of vitamins and minerals in managing non-scarring alopecia but reports no clinical results; the authors advocate for further controlled trials to explore these relationships.
95 citations
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February 2018 in “Dermatology and Therapy” This review discusses the role of nutraceuticals in combating skin aging but reports no new clinical results, focusing on their mechanisms of action and potential effectiveness for dermatologists.
18 citations
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October 2014 in “Experimental Biology and Medicine” This study found that feeding mice high levels of dietary vitamin A increased WNT signaling, which activated hair follicle stem cells and may have accelerated alopecia areata progression.