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This study found that a nanofiber wound dressing made of CQD/Si NP/SF significantly inhibits bacterial growth and accelerates skin wound healing and hair follicle regeneration in animal models.

This study found that low massage frequencies like 4.2 Hz enhance nanoparticle penetration into hair follicles more effectively than higher frequencies, indicating potential applications in therapeutic and cosmetic delivery.

This study developed and tested a new injectable hydrogel for chronic diabetic wounds, reporting significant improvements in wound healing through enhanced angiogenesis, epithelization, and reduction of inflammation and infection in animal models.

This study found that PEGylation of nanoparticles enhances their penetration into hair follicles, with higher molecular weight PEG resulting in deeper follicular delivery.

This study found that hydrophobic lipid-coated silica nanoparticles penetrated deeper into human stratum corneum compared to their hydrophilic counterparts, highlighting the influence of surface polarity on skin penetration.

This study suggests that a biomaterial-based approach using microneedles and ion solutions to deliver SiO3 2− ions may disrupt inflammatory cycles and improve outcomes in inflammatory dilated cardiomyopathy (iDCM).

In this study, researchers developed a composite electrospun wound dressing containing strontium zinc silicon bioceramics, which significantly activated hair follicle stem cells and promoted hair follicle and capillary regeneration in deep burn wounds, suggesting a promising approach for burn wound healing.

In this clinical trial, the researchers observed that a biotin and silica supplement reduced hair fall, increased hair growth rate, and improved skin elasticity, hydration, and nail quality over 90 days without adverse effects.

This review highlights how silicate-based bioceramics and bioglasses could enhance skin regeneration for wound healing by promoting angiogenesis, stimulating collagen deposition, and providing anti-infection benefits, while also examining their integration with emerging technologies and current applications.

This study found that silica nanoparticles penetrate the outer stratum corneum of human skin, with surface hydrophobization potentially enhancing this penetration.

This study explored the use of manganese-doped calcium silicate nanowire-incorporated alginate hydrogels (MCSA hydrogels) for treating melanoma and promoting wound healing, finding that these hydrogels effectively ablate melanoma under near-infrared irradiation and enhance vascular endothelial cell activity for tissue regeneration.

This study presents a modified method for synthesizing ~1 nm zinc oxide nanoparticles within the pores of SBA-11, maintaining the mesoporous structure without requiring alcohol reflux or basic solution reaction steps.

This study found that using nanoporous silica entrapped lipid-drug complexes enhanced the solubility and bioavailability of dutasteride in beagle dogs.

In this study, researchers developed a new method for producing dissolving microneedle array patches containing mesoporous silica nanoparticles, successfully confirming nanoparticle deposition and release in both ex vivo and in vivo models.

This study found that cefazolin-loaded silica nanoparticles embedded in polycaprolactone nanofibers successfully inhibited Staphylococcus aureus growth while maintaining stem cell viability, suggesting their potential use in wound healing.

This study found that Na2SiO3 accelerated hair regrowth in mice, indicating potential for treating alopecia, though it did not significantly alter enzyme activity compared to distilled water.

In this study, researchers developed a nanocomposite microneedle patch containing copper/zinc dual-doped silica nanoparticles, which release substances to promote hair follicle regeneration by targeting various pathophysiological aspects of androgenic alopecia, presenting an effective anti-hair loss treatment strategy.

In this animal study, applying a combination of inositol-stabilized arginine silicate complex and magnesium biotinate promoted hair growth but not nail growth.

This study observed that a combination of arginine silicate complex and magnesium biotinate significantly improved hair and nail growth in rats.

This article proposes a novel approach to remodel the microenvironment of radiotherapy-induced skin defects, highlighting the lack of a standardized animal model as a barrier to progress in this field.

This study suggests that inorganic magnesium silicate sprays can improve burn wound repair and promote regeneration of skin appendages, showing superior results compared to commercial wound healing products in animal models.

This study found that dissolving microneedle array patches containing mesoporous silica nanoparticles can deliver antigen-loaded nanoparticles into mice effectively, inducing strong immune responses similar to traditional subcutaneous injection.

This study demonstrates that a newly developed nanocomposite microneedle patch, releasing copper and zinc ions along with quercetin, effectively promotes hair follicle regeneration in androgenic alopecia by targeting various pathophysiological aspects of hair loss.

Created material boosts hair growth and kills bacteria for wound healing.

In this study, researchers found that silica nanoparticles synthesized using cold plasma showed a higher biofilm inhibition effect on Staphylococcus aureus and Escherichia coli compared to those made with a magnetic stirrer.

This study suggests that bioactive ceramics could be an effective universal strategy for treating musculoskeletal disorders by targeting the Piezo1-modulated intracellular calcium pathway during bone and muscle formation.

This study analyzed 853 articles to reveal that research on silica-based nanobiomaterials in regenerative medicine has rapidly increased, with distinct regional differences in impact and emerging focus areas in drug delivery and wound healing.

Vitamin D3-coated nanoparticles effectively deliver caffeine for alopecia treatment with minimal side effects.

This study developed caffeine-loaded nanoparticles coated with ultradeformable liposomes for better hair follicle delivery, showing non-cytotoxicity and potential to reduce oxidative stress in DHT-damaged cells, suggesting an alternative treatment for androgenetic alopecia.