research The Role of Paracellular Transport in the Intestinal Absorption and Biopharmaceutical Characterization of Minoxidil
Minoxidil's absorption is too variable for it to be a reliable reference drug.
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780-810 / 1000+ resultsresearch Designed, Synthesis, In Vitro and Computational Analyses of Anticancer Nicotinamide Derivatives
Compound N4 effectively kills breast cancer cells and compounds N2 and N3 have strong antibacterial and antifungal properties.
research Logic-Based Modeling and Drug Repurposing for the Prediction of Novel Therapeutic Targets and Combination Regimens Against E2F1-Driven Melanoma Progression
Cialis and Finasteride could be repurposed to treat aggressive melanoma.
research Glutamic Acid Promotes Hair Growth in Mice
Glutamic acid helps mice grow hair.
research Finasteride Inhibits Epinephrine Synthesis in Humans: Implications for Sexual Dysfunction
Finasteride may cause sexual dysfunction by reducing epinephrine levels.
research Genome-Wide Gene Expression Dataset Used to Identify Potential Therapeutic Targets in Androgenetic Alopecia
Five molecular elements identified as potential future targets for hair loss therapy.
research The Genomic Variation In Textured Hair: Implications In Developing A Holistic Hair Care Routine
Afro-textured hair needs specialized care due to its unique genetic and structural properties.
research Essential Oils-Based Nanoemulsion Formulation Boosts Hair Growth in C57BL/6 Mice Compared to Minoxidil 2%
Essential oils in a nanoemulsion help hair grow better than minoxidil 2% in mice.
research Modeling the Onset of Senescence-Associated Secretory Phenotype Predicts Therapeutic Targets
The research found that blocking a gene called NEMO can potentially prevent harmful effects of aging at the cellular level.
research Clinical Snippets: R-Spondin2 Amplifies Wnt Signaling for Hair Growth, Gene Expression Differences in Balding Scalp, IKB Regulates hBD2 in Psoriasis, ß-Defensin Gene Cluster and Hidradenitis Suppurativa, Autoantigen Epitopes in Alopecia Areata
New treatments for hair growth and psoriasis may be possible, and gene differences could affect baldness and the severity of skin conditions.
research A Peptide Derivative with Known Anti-Wrinkle Properties Identified as Potent Dipeptidylpeptidase-4 Inhibitor
A peptide known for reducing wrinkles also effectively inhibits an enzyme linked to skin inflammation and acne.
research Thyroid Hormones and Androgens Differentially Regulate Gene Expression in Testes and Ovaries of Sexually Mature Silurana Tropicalis
Thyroid hormones and androgens affect gene expression in frog reproductive organs differently between males and females.
research Clinical Snippets: Hair Growth, Androgenetic Alopecia, Psoriasis, Hidradenitis Suppurativa, and Alopecia Areata
R-spondin2 may help treat hair loss, gene differences could explain baldness, a peptide's regulation is linked to psoriasis, B-defensin gene copies may affect a skin condition's risk and severity, and potential markers and targets for alopecia areata were identified.
research Keratinocytes Regulate the Function of Melanocytes
Keratinocytes control how melanocytes work.
research Management of Hair Loss Diseases
New treatments for hair loss show promise, but more development is needed, especially for tough cases.
research Dengue-Associated Telogen Effluvium: A Report of 14 Patients
Dengue fever can cause a temporary type of hair loss called telogen effluvium.
research Efficacy and Safety of Tofacitinib Therapy in Asian Patients with Severe Alopecia Areata
Tofacitinib helps regrow hair in severe alopecia patients, but more research is needed.
research Concomitant Occurrence of Acneiform Eruption, Alopecia Areata, and Urticaria During Adalimumab Treatment in a Patient With Pustulosis Palmoplantaris: Case Report and Literature Review
A patient with PPP had rare skin reactions to adalimumab, which improved after stopping smoking and continuing acitretin.
research Diagnostic Accuracy Measures for Vertical and Transverse Scalp Biopsies in Cicatricial and Non-Cicatricial Alopecias
Transverse scalp biopsies are more accurate for diagnosing non-cicatricial alopecia, but examining both types is best for accuracy.
research Quantitative Assessment of Female Pattern Hair Loss
Computer-aided imaging system helps measure balding area in female pattern hair loss.
research Excimer Lamp as an Effective Alternative Treatment for Severe Alopecia Areata
The excimer lamp is a safe and effective treatment for severe alopecia areata.
research Platelet-Rich Plasma in the Treatment of Alopecia Areata: A Retrospective Evaluation of 17 Patients
PRP treatment may help with alopecia areata, especially in newer cases.
research Survey of Dermoscopy Use by Taiwanese Dermatologists
About half of Taiwanese dermatologists use dermoscopy, mainly to improve diagnosis and detect cancer early, but cost and lack of training limit its wider use.
research Atrichia with Papular Lesions in a Taiwanese Patient Without Hairless (HR) Gene Mutation
A Taiwanese patient had hair loss and skin bumps without the usual gene mutation, suggesting other genetic factors might be involved.
research Dermoscopic Features of Discoid Lupus Erythematosus
Dermoscopy is useful for diagnosing and monitoring discoid lupus erythematosus by showing specific skin patterns.
research Lipedematous Alopecia with Mucinosis: Report of the First Case in Taiwan
Taiwan reported its first case of a rare scalp condition with no clear cause or treatment.
research Serum Levels of Minerals and Vitamins in Two Categories of Female Alopecia Subjects Using Hair Relaxer
Women using hair relaxers with alopecia had lower zinc levels, suggesting zinc deficiency might contribute to hair loss.
research Investigating the Role of Various Extracellular Matrix in Androgenetic Alopecia: Insights from Immunostaining and Quantitative Analysis - A Pilot Study
ECM changes may play a role in hair loss, with differences between males and females.
research Upadacitinib for the Treatment of Alopecia Areata – A Case Report
Upadacitinib helped regrow hair in a severe alopecia areata patient but stopping treatment caused hair loss to return.
research Current Understanding and Treatment of Sex Hormone-Related Hair Diseases
Sex hormones affect hair growth and loss, and treatments for related hair diseases include various medications, hair transplantation, and light therapy.