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This study found that β-catenin stabilization in specific mammary epithelial lineages leads to cellular changes and the formation of hyperplastic lesions, revealing its role in initiating mammary neoplastic development.

This study found that the systemic wrinkled skin phenotype in Xiang pigs involves gene expression changes and genetic variations associated with oxidative stress and extracellular matrix components, resembling features seen in Shar-Pei dogs.

This study found that in adult mouse skin, reduced levels of histone H3 K4/K9/K27me3 during hair follicle stem cell quiescence are linked to proper tissue homeostasis.

Genetics, hormones, and microbiome changes contribute to hidradenitis suppurativa.

This study developed 3DEEP, a tissue clearing and spatial transcriptomic method, to map hair follicle development in a single time point from a 12-hour-old mouse, detailing molecular stages, signaling dynamics, and structural changes within developing follicles.

This study found that inherited color dilution in Rex rabbit hair follicles is associated with DNA methylation changes, contributing to understanding the epigenetic regulation of rabbit pigmentation.

This study explored the decline in cashmere production in Inner Mongolian cashmere goats through RNA-seq analysis, finding that AKT1 expression and related signaling pathways are age-dependent, with peak AKT1 upregulation at 12 months aligning with peak cashmere production.

This narrative review reported that a variety of lifestyle-based interventions, such as specific dietary changes and physical activity, along with adjunctive therapies, have potential benefits in managing metabolic and hormonal outcomes in women with PCOS, although the variable study quality suggests further research is needed.

This study found that elevated luteinizing hormone levels were significantly associated with female pattern hair loss, and implicated LH/LHR signaling in the aging and damage of hair follicles.

This source reviews mechanisms and existing treatments for hair aging, highlighting factors like oxidative stress and DNA repair defects that affect hair follicle and stem cell function, and discusses research limitations and future directions in the field.

This study found that deleting Ube2n in adult mouse skin leads to inflammation and other skin changes, and identifies IRAK1/4 as potential treatment targets for inflammatory skin disorders.

This study found that bioelectric and biochemical signaling mechanisms coordinate collective cell movement during chicken feather bud morphogenesis, suggesting a potential new angle for research in skin development and wound healing.

This study found that the BMP antagonist noggin induces hair growth in postnatal skin by neutralizing BMP4's inhibitory activity, potentially mediated by changes in Shh expression.

In this study, epidermal Notch activation increased jagged 1 expression, leading to skin changes like thickening and blistering, with these effects inhibited when jagged 1 was absent.

This study observed that the OCIAD2 and DCN genes in Liaoning cashmere goats have opposite effects on hair growth by interacting with the TGF-β signaling pathway, influencing follicle morphogenesis and periodic changes.

This research found that escin, when applied topically, enhances blood flow in human skin and promotes changes in endothelial cell signaling pathways, suggesting potential benefits for improving cutaneous microcirculation.

In this study, researchers observed that fasting-induced molting in laying hens led to increased thyroid hormones, which may regulate feather molting by affecting hair follicle growth through specific signaling pathways, highlighting molecular changes during induced molting.

This article discusses various management strategies for polycystic ovarian syndrome but reports no new clinical results, emphasizing the need for comprehensive treatment approaches involving lifestyle changes, pharmaceuticals, and potential genetic insights.

This review explores weight loss interventions during gestation, emphasizing incretin-based therapies' potential to enhance reproductive health and address metabolic changes for better maternal and fetal outcomes.

In this laboratory study, researchers observed that mouse vascular endothelial cells exhibit dynamic changes after exposure to ionizing radiation, including a transient endothelial subpopulation that facilitates vascular-epidermal communication and skin repair, with shifting roles in angiogenesis and immune surveillance over time.

In this study, Lrig1-positive stem cells in mouse hair follicles were found to be essential for sebaceous gland formation and maintenance, with their depletion causing a temporary loss of these glands and changes in cellular differentiation.

In this study, researchers explored hair follicle development in Qianhua Mutton Merino sheep, identifying key genes like KRT27 and IGF-2 that impact this process, with findings suggesting significant molecular changes as sheep mature from newborn to one year old.

This study found that Melamax®, originally developed as an eco-friendly hair dye, provides significant protection against ultraviolet-induced oxidative and inflammatory damage in keratinocytes by modulating gene expression and signaling pathways, highlighting its dual potential for cosmetic coloration and skin photoprotection.

In this study, researchers used the CRISPR/Cas9 system to edit the FGF5 gene in Dorper sheep, observing increased density and finer wool, along with changes in cortisol levels and antioxidant enzyme activity linked to hair follicle development.

This study examined the effects of finasteride on human Leydig cells and found altered methylation in dopaminergic pathways, suggesting potential epigenetic contributions to post-finasteride syndrome, warranting further investigation.

This study examined the formation of acquired curved hair and found that the fusion of hair matrix cells during follicle regeneration contributes to asymmetric follicle shapes and curved hair, potentially linked to changes in type IV collagen and protein expression levels.

This hypothesis paper suggests that sexual and cognitive dysfunctions reported by some men after using finasteride and dutasteride may stem from vascular and tissue changes in penile tissue triggering broader inflammatory effects.

Organ transplant recipients have a higher risk of skin cancer over time, atopic dermatitis skin shows unusual bacterial and fungal patterns, a new tool for measuring hidradenitis suppurativa severity was created, and gene expression changes in male baldness suggest new treatments.

This study found that in mice, type XVII collagen is essential for controlling epidermal cell proliferation through Wnt signaling, with its deficiency or altered distribution leading to skin hyperproliferation and aging-like changes.

This study found that retinoic acid and a retinol complex formulation showed different permeation and compound localization in a skin equivalent model, with unique lipid changes observed with only the retinol formulation.