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Abnormal Hedgehog signaling in blood cancers may help tumors grow and resist chemotherapy, suggesting potential for targeted treatments.

The TCL1 transgenic mouse model is useful for understanding human B-cell leukemia and testing new treatments.

Skin side effects from EGFR inhibitor cancer treatment can be managed effectively, often without stopping the medication.

Effective, well-tolerated, and affordable treatments are needed for recurrent ischemic priapism.

Anticancer drugs are increasingly found in surface waters, and their long-term environmental effects are not well understood, requiring better testing methods.

Inhibiting 5α-reductase can help reduce prostate cancer risk and improve treatment.

The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.

DHEA stimulates skin oil glands and could help postmenopausal women, with potential for acne and excessive hair growth treatments.

Wnt signaling is crucial for skin and hair development and its disruption can cause skin tumors.

Blocking a specific enzyme might help treat obesity and diabetes, but more research is needed to ensure it's safe.

Lysophosphatidic acid is important for skin health and disease, and could be a target for new skin disorder treatments.

Retinoids increase steroid sulfatase activity in leukemia cells through RARα/RXR and involves certain pathways like phosphoinositide 3-kinase and ERK-MAP kinase.

Ruxolitinib treatment may cause eyelash growth.

The skin protects the body, regulates temperature, senses touch, and makes vitamin D.

Blocking EGFR in skin cells doesn't majorly increase inflammation markers.

Understanding hair growth involves complex interactions between molecules and could help treat hair disorders.

New treatments for Alopecia Areata show promise but need to be more effective and affordable.

No single ideal JAK inhibitor for alopecia areata has been determined; JAK3 inhibitors may be promising with fewer side effects.

Removing UBE2N from skin cells causes inflammation and immune response, which can be lessened with specific inhibitors.

Understanding and managing side effects of hedgehog pathway inhibitors can improve treatment for advanced basal cell carcinoma.

New treatments like JAK inhibitors show promise for reversing alopecia areata.

Individualized treatment plans are crucial for children with alopecia areata, with promising options like JAK inhibitors showing significant hair regrowth.

Oxidative stress plays a significant role in alopecia areata, and new treatments may include JAK inhibitors and antioxidants.

Centipeda minima extract helps hair grow by activating important growth signals and could be a promising hair loss treatment.

Blocking JAK3 signaling can reverse hair loss from alopecia areata.

Melatonin helps broccoli roots produce anti-cancer compounds by controlling nitric oxide and hydrogen peroxide levels.

Birt–Hogg–Dubé syndrome is a rare genetic condition causing skin lesions, lung cysts, and a higher chance of kidney cancer.

Low androgen levels might delay prostate cancer but could lead to more aggressive, therapy-resistant cancers.

A protein called IL-36γ causes skin side effects from certain cancer treatments when combined with a common skin bacteria.

Finasteride and dutasteride are equally effective and safe for treating benign prostatic hyperplasia.