research Integrated miRNA and mRNA Analysis Provides New Insight into Mechanism of Dermal Papilla in Androgenetic Alopecia
Increased cell death and reduced cell growth in hair follicles contribute to baldness.
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30 / 479 results research First-In-Man Clinical Trial of the Oral Pan-AKT Inhibitor MK-2206 in Patients With Advanced Solid Tumors
MK-2206 was safe and effectively blocked AKT signaling in cancer patients, warranting more trials.
research Microimaging of Hairless Rat Skin by Magnetic Resonance at 900 MHz
MRI can effectively image skin structures noninvasively.
research Human Mesenchymal Stem Cell-Derived Conditioned Media for Hair Regeneration Applications
Stem cell therapy could be a promising alternative for hair regrowth with fewer side effects.
research Fibrosing Alopecia in a Pattern Distribution in 16 African-Descent and Hispanic Female Patients: A Challenging Diagnosis
FAPD is a possible diagnosis for hair loss in patients of color and requires multiple evaluations for accurate diagnosis.
research Diagnosis: Alopecia Areata or Not?
Scalp biopsies are essential for accurately diagnosing alopecia areata.
research Histologic Study of the Regeneration Process of Human Hair Follicles Grafted onto SCID Mice after Bulb Amputation
Human hair follicles can regenerate and recover after severe injury by going through a brief abnormal resting phase before growing again.
research Evaluation of Morphological and Histological Changes in Transplanted Hair Follicles
Transplanted hair follicles show significant changes after FUE, needing more research.
research Adipose Mesenchymal Stromal Cell-Derived Exosomes Carrying MiR-122-5p Antagonize the Inhibitory Effect of Dihydrotestosterone on Hair Follicles by Targeting the TGF-β1/SMAD3 Signaling Pathway
ADSC-Exos with miR-122-5p can help treat hair loss by promoting hair growth.
research Analysis of Dermal Papilla Cell Interactome Using STRING Database to Profile the Ex Vivo Hair Growth Inhibition Effect of a Vinca Alkaloid Drug, Colchicine
Colchicine can inhibit hair growth by affecting cell activity and protein expression in hair follicles.
research A Simple Assay for the Study of Human Hair Follicle Damage Induced by Ionizing Irradiation
Ionizing radiation damages human hair follicles by stopping cell growth, causing cell death, disrupting color, and increasing stress and damage markers.
research Formulation and In Vivo Assessment of Topical Polyherbal Hair Serum to Promote Hair Growth
The polyherbal hair serum helped prevent hair loss and improved hair growth better than the usual treatment.
research Dissecting the Impact of Chemotherapy on the Human Hair Follicle
Chemotherapy damages hair follicles, causing hair loss and other cellular changes.
research Pigmentation of Hair on Transplanted Skin in Hooded Rats
Transplanted skin on hooded rats often grows white hair instead of black.
research Hair Follicle Plasticity with Complemented Immune-Modulation Following Follicular Unit Extraction
Transplanted hair follicles can change and adapt to new areas of the body, with the immune system possibly playing a role in this adjustment.
research In Vivo and In Vitro Evaluation of Hair Growth Potential of Hibiscus Rosa-Sinensis Linn.
Hibiscus rosa-sinensis leaf extract helps hair grow longer and faster.
research Characterization and Quantification of Wound-Induced Hair Follicle Neogenesis Using In Vivo Confocal Scanning Laser Microscopy
In vivo confocal scanning laser microscopy is an effective, non-invasive way to study and measure new hair growth after skin injury in mice.
research A Novel Approach for Follicular Delivery of Minoxidil for Treatment of Alopecia
Scientists developed a new method to deliver alopecia treatment directly to hair follicles, which could be a promising treatment for hair loss and other hair diseases.
research Targeted Elimination of Follicular Label-Retaining Cells by Photo-Induced Cell Killing Caused a Defect in Follicular Renewal in Mice
Killing specific cells in hair follicles can lead to hair growth problems in mice.
research The Microanatomy of Human Skin in Aging
Aging skin shows thinner layers, fewer hair follicles, and new biomarkers like increased space between cells and smaller sebaceous glands.
research Histology of the Human Hair Follicle
Understanding hair follicle structure is key for treating hair disorders and could help develop new treatments.
research Activation of mTORC1 Signaling Is Required for Timely Hair Follicle Regeneration from Radiation Injury
mTORC1 signaling needed for quick hair follicle recovery after radiation damage.
research Hair Growth-Promoting Effects of Rosehip (Rosa canina L.) Seed Oil in C57BL/6 Mice
Rosehip Seed Oil may help hair grow by activating important growth pathways and increasing hair follicle size in mice.
research Androgenetic Alopecia: Combing the Hair Follicle Signaling Pathways for New Therapeutic Targets and More Effective Treatment Options
New treatments for hair loss may target specific pathways and generate new hair follicles.
research Morphological Approach to Hair Disorders
Accurate clinical, histological, and genetic methods are key for understanding and treating hair disorders.
research Follicular Streamers (Stelae) in Scarring and Non-Scarring Alopecia
Hair root sheaths are more common in non-scarring hair loss and help diagnose the type of hair loss.
research Permanent Alopecia After Systemic Chemotherapy: A Clinicopathological Study of 10 Cases
Chemotherapy can cause permanent, non-reversible hair loss similar to pattern baldness.
research Promotion of Homology-Directed DNA Repair by Polyamines
Polyamines help fix DNA damage accurately in cells.
research Cell Death as an Architect of Adult Skin Stem Cell Niches
Cell death shapes skin stem cell environments, affecting inflammation, repair, and cancer.
research Tofacitinib Loaded Squalenyl Nanoparticles for Targeted Follicular Delivery in Inflammatory Skin Diseases
Tofacitinib nanoparticles can safely and effectively treat alopecia areata by targeting hair follicles.