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Higher DHT levels are linked to worse heart changes in severe aortic valve stenosis patients.

The enzyme 5α-reductase is key in causing psychotic-like effects from sleep deprivation.

The new method accurately detects illegal hair-growth drugs in dietary supplements.

The nanocrystalline suspension effectively delivers dutasteride over time with minimal inflammation.

Conditioned media from mesenchymal stem cell cultures could be a more effective alternative for regenerative therapies, but more research is needed.

Standardized procedures are crucial for collecting and preparing biological samples to ensure accurate clinical metabolomics results.

The anti-viral drug Elvitegravir may protect brain cells from damage related to neurodegenerative diseases.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Eicosanoids are crucial for skin health, and targeting their pathways may help treat skin conditions.

Maxillariinae orchids contain 62 compounds with potential health benefits, including treating skin conditions and diseases like cancer and diabetes.

Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.

Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.

The method can measure multiple steroids in human hair to study long-term steroid metabolism, especially in newborns and children.

The document concludes that diagnosing PCOS in teenagers is difficult and should focus on specific hormone levels and menstrual irregularities, while also considering treatment for symptoms and related health issues.

Girls with PCOS have higher levels of certain androgens, which are linked to excess hair growth, but these androgens don't help diagnose PCOS.

The study concluded that the arachidonic acid pathway and the protein KRT79 play a role in determining the fineness of cashmere.

Biotin supplements improved skin and hair problems in a girl with biotinidase deficiency.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

Mutations in the HEPHL1 gene cause abnormal hair and cognitive issues.

Finasteride can have lasting negative effects on brain function and behavior by disrupting neurosteroid production.

Androgens and androgen receptors are important for metabolic health, affecting how the body uses glucose and fats through mitochondrial function.

Taking Dutasteride with Ketoconazole can increase Dutasteride's effects and side effects.

Single-cell engineered biotherapeutics show promise for skin treatment but need more research and trials.

Polycystic Ovary Syndrome (PCOS) is a common condition in women that can cause metabolic, reproductive, and psychological issues, and requires lifestyle changes and medication for management.

Method accurately measures finasteride concentration in medicine.

Hair thinning causes stem cell loss through a process involving Piezo1, calcium, and TNF-α.

Some plants like Eclipta alba, Nardostachys jatamansi, and Rumex japonicus may help hair growth.

BcFLA1 protein is crucial for root hair growth in response to low phosphate in Brassica carinata.

New method accurately measures finasteride and M3 in urine, helping evaluate pharmacokinetics.

Researchers found that most genes affecting drug responses are not fully covered by commercial SNP chips, suggesting the need for more comprehensive tools to optimize drug selection based on genetics.