384 citations,
June 2005 in “Genes & development” β-catenin is essential for stem cell activation and proliferation in hair follicles.
305 citations,
June 2012 in “Nature” Hair regeneration needs dynamic cell behavior and mesenchyme presence for stem cell activation.
277 citations,
July 2002 in “Molecular Endocrinology” Removing part of the vitamin D receptor stops vitamin D from working properly.
270 citations,
March 2012 in “Dermatologic Surgery” Platelet-rich plasma can potentially promote hair growth by stimulating cell growth and increasing certain proteins.
212 citations,
September 2008 in “Journal of The American Academy of Dermatology” Minoxidil and finasteride treat hair loss in men, while minoxidil treats hair loss in women.
211 citations,
April 2013 in “Development” More dermal papilla cells in hair follicles lead to larger, healthier hair, while fewer cells cause hair thinning and loss.
194 citations,
May 2000 in “Journal of Investigative Dermatology” The hedgehog signaling pathway is crucial for hair growth but not for the initial creation of hair follicles.
165 citations,
August 2013 in “Lasers in Surgery and Medicine” Low-Level Laser Therapy is effective and safe for hair growth with minimal side effects.
159 citations,
September 2001 in “European Journal of Cancer Care” Chemotherapy-induced hair loss significantly affects patients' well-being, and nurses are key in helping them cope, but more research is needed to find effective treatments.
134 citations,
January 2010 in “Biomedical research” Low oxygen conditions increase the hair-growing effects of substances from fat-derived stem cells by boosting growth factor release.
117 citations,
March 2017 in “Nature Communications” Macrophages help regrow hair by activating stem cells using AKT/β-catenin and TNF.
117 citations,
March 2013 in “Journal of the European Academy of Dermatology and Venereology” No effective treatment for frontal fibrosing alopecia was found, but oral 5-alpha-reductase inhibitors had the best response; for lichen planopilaris, topical corticosteroids were commonly used but had a high relapse rate.
109 citations,
December 2003 in “American Journal of Pathology” Fetal wound healing changes with development, affecting inflammation and collagen, which may influence scarring.
100 citations,
June 2011 in “Journal of The American Academy of Dermatology” 5% minoxidil foam once daily works as well as 2% minoxidil solution twice daily for female hair growth and is more convenient.
90 citations,
January 2009 in “Journal of cosmetic and laser therapy” Low-level laser therapy might help hair growth, but more research is needed.
81 citations,
August 2014 in “Lasers in Surgery and Medicine” Red light therapy is safe and effectively increases hair growth in women with hair loss.
76 citations,
January 2019 in “Nanoscale” Created material boosts hair growth and kills bacteria for wound healing.
73 citations,
March 2009 in “Seminars in Cutaneous Medicine and Surgery” The document concludes that accurate diagnosis of hair disorders is crucial and requires a range of diagnostic methods.
71 citations,
January 2015 in “Journal of molecular cell biology/Journal of Molecular Cell Biology” mTOR signaling helps activate hair stem cells by balancing out the suppression caused by BMP during hair growth.
62 citations,
April 2004 in “Expert Opinion on Pharmacotherapy” Finasteride effectively treats male pattern baldness, improving hair growth and density.
58 citations,
December 2017 in “Journal of The European Academy of Dermatology and Venereology” Microneedling can help stimulate hair growth, especially when used with other treatments, but it's not better than existing therapies.
53 citations,
March 2014 in “Growth Hormone & IGF Research” IGF-1 injections help mice grow more hair by increasing cell growth and blocking a hair growth inhibitor.
53 citations,
May 1990 in “Journal of Dermatology” Minoxidil speeds up hair growth in rats without prolonging growth phase.
49 citations,
February 2020 in “Scientific reports” The nanohybrid system significantly improved wound healing and showed strong antibacterial activity.
48 citations,
June 2013 in “Journal of Dermatological Science” Valproic acid may help hair grow and could be a safe treatment for hair loss.
46 citations,
September 2010 in “Southern Medical Journal” Hair loss treatments include medications and new methods like low-level light therapy, which may work by boosting cell activity and blood flow.
43 citations,
July 2013 in “Pharmacological reviews” New research on prostamide F2α has led to treatments for glaucoma and eyelash growth and may have more medical uses.
41 citations,
July 2012 in “Stem Cells and Development” Low-dose UVB light improves hair growth effects of certain stem cells by increasing reactive oxygen species.
38 citations,
July 2021 in “ACS Nano” Microneedles help treat hair loss by improving hair surroundings and promoting growth.
38 citations,
May 2009 in “European journal of dermatology/EJD. European journal of dermatology” TrichoScan® is a reliable tool for measuring hair growth, providing quicker and more consistent results than manual methods.