research A Prospective, Randomized Trial Comparing Flutamide (250 mg/d) and Finasteride (5 mg/d) in the Treatment of Hirsutism
Flutamide reduces hair growth better but has more side effects.
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research Effect of Finasteride, a 5 Alpha-Reductase Inhibitor, on Serum Gonadotropins in Normal Men
Finasteride doesn't affect hormone levels in normal men.
research Cloning, Expression, and Characterization of Rhesus Macaque Types 1 and 2 5alpha-Reductase: Evidence for Mechanism-Based Inhibition by Finasteride
Finasteride inhibits enzyme activity in rhesus macaques, suggesting they're useful for evaluating similar drugs.
research Combination of an Antiandrogen and a 5α-Reductase Inhibitor: A Further Step Towards Total Androgen Blockade?
Using two drugs together, Flutamide and 4-MA, is more effective for blocking male hormones than using each one alone.
research Potential Factors Contributing to Androgenetic Alopecia
Male pattern baldness may be caused by factors like poor blood circulation, scalp tension, stress, and hormonal imbalances, but the exact causes are still unclear.
research 5α-Reductase Inhibitors: Evaluation of Their Potential Confounding Effect on GC-C-IRMS Doping Analysis
5α-reductase inhibitors can interfere with doping tests by masking banned substances.
research Comparison of Dermatology Diagnoses During COVID-19 Period with Previous Year: What Has Changed?
During the COVID-19 pandemic, some skin conditions became more common while others decreased.
research Aging Well
Eating fewer calories may slow aging and removing old cells can increase lifespan in mice.
research Growth of the Hair
Hair growth is cyclic and influenced mainly by local factors.
research Photographic Documentation of Hair Growth in Androgenetic Alopecia
Photographic documentation crucial for evaluating hair growth in androgenetic alopecia.
research Four-Amino Acid Segment in Steroid 5 Alpha-Reductase 1 Confers Sensitivity to Finasteride, a Competitive Inhibitor
Four-amino acid part makes enzyme sensitive to finasteride.
research Stem Cells and the Circadian Clock
The circadian clock influences the behavior and regeneration of stem cells in the body.
research Outcome of Long-Term Treatment with the 5α-Reductase Inhibitor Finasteride in Idiopathic Hirsutism: Clinical and Hormonal Effects During a 1-Year Course of Therapy and 1-Year Follow-Up
Finasteride effectively reduces hair growth in women with idiopathic hirsutism, but requires careful contraception during treatment.
research Characterization of a 190-Kilobase Pair Domain of Human Type I Hair Keratin Genes
The 190-kbp domain contains all human type I hair keratin genes, showing their organization and evolution.
research Ovarian Morphology Is a Marker of Heritable Biochemical Traits in Sisters with Polycystic Ovaries
Polycystic ovarian shape is a genetic sign of PCOS and its hormonal and metabolic features can be inherited.
research Perifollicular Erythema as a Trichoscopy Sign of Progression in Frontal Fibrosing Alopecia
Perifollicular erythema can indicate active frontal fibrosing alopecia.
research The Development of Several Organs and Appendages Is Impaired in Mice Lacking Sp6
Mice without the Sp6 gene have problems developing several body parts, including hair, teeth, limbs, and lungs.
research Unilateral Gynecomastia Induced by Treatment With 1 mg of Oral Finasteride
Finasteride can cause one-sided breast enlargement, which disappears after stopping the drug.
research Hair Shaft Dysplasias
Hair shaft dysplasias are abnormal hair conditions that can be inherited or acquired and may signal other health issues, with limited treatment options available.
research Identification of Finasteride Metabolites in Human Bile and Urine by High-Performance Liquid Chromatography/Tandem Mass Spectrometry
Finasteride breakdown products found in bile and urine, helps understand drug safety and effectiveness.
research Frontal Pseudoalopecia in History: Part 1—Fashionable Forms
In the Middle Ages, European noblewomen intentionally removed forehead hair to be fashionable, showing how beauty standards can affect the perception of hair loss.
research Alopecia Areata, Primary Sclerosing Cholangitis, and Ulcerative Colitis: Autoimmunity and Apoptosis as Common Links?
The conditions alopecia areata, primary sclerosing cholangitis, and ulcerative colitis may be linked by shared autoimmune and cell death mechanisms.
research Tattoos: A Summary Knowledge for the Practicing Clinician
Clinicians should understand tattoos to manage health issues, as tattoos can cause complications and affect medical assessments.
research Photographic Documentation of Hair Growth in Androgenetic Alopecia
High-quality photos help track hair growth progress in androgenetic alopecia patients.
research Disorders of Hair Growth and the Pilosebaceous Unit: Facts and Controversies
Experts don't fully agree on how to diagnose certain hair growth disorders and more research is needed to understand them better.
research Human Scalp Hair: Modulation by Various Factors and Hormones - Do Estrogens Inhibit or Stimulate? A Perplexing Perspective
The effects of estrogen on human scalp hair growth are unclear and need more research.
research Finasteride Inhibits 5α-Reductase Activity in Human Dermal Fibroblasts: Prediction of Its Therapeutic Application in Androgen-Related Skin Diseases
Finasteride helps treat skin issues like acne and baldness by blocking testosterone conversion.
research Optimizing Skin Disease Diagnosis: Harnessing Online Community Data With Contrastive Learning and Clustering Techniques
Researchers improved a skin disease diagnosis model using online images, achieving up to 49.64% accuracy.
research Hormonal Manipulation with Finasteride or Oral Contraception Does Not Influence Incidence of Renal Cell Carcinoma
research Letter to the Editor: Characteristics of Men Who Report Persistent Sexual Symptoms After Finasteride Use for Hair Loss
Finasteride use may cause sexual dysfunction; more research needed.